From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 27-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_00994 [new locus tag: SPNA45_RS14060 ]
  • pan locus tag?: PNEUPAN001558000
  • symbol: SPNA45_00994
  • pan gene symbol?: —
  • synonym:
  • product: putative radical SAM superfamily protein (pseudogene)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_00994 [new locus tag: SPNA45_RS14060 ]
  • symbol: SPNA45_00994
  • product: putative radical SAM superfamily protein (pseudogene)
  • replicon: chromosome
  • strand: +
  • coordinates: join(987918..988424,988428..988874)
  • length: 954
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: HE983624 join(987918..988424,988428..988874) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_2201 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAAAGTCATGAAATCTTATAATACCTTGAATGATTATTATCGAAAACTCTTTGGAGAA
    AAGACTTTTAAAGTCCCTATTGATGCGGGATTTGACTGTCCCAATCGTGATGGAACTGTG
    GCTCATGGAGGCTGTACTTTTTGTACGGTTTCAGGTTCTGGAGATGCCATTGTAGCCCCA
    GATGCGCCTATCCGTGAGCAATTTTATAAGGAAATTGACTTTATGCACCGTAAGTGGCCG
    GATGTTCAGAAGTATCTGGTTTATTTTCAAAGTTTTACCAACACCCATGAAAAGGTGGAA
    GTTATTCGAGAGCGTTATGAACAGGCTATCAATGAGCCAGGTGTGGTAGGTATCAATATT
    GGAACGCGCCCAGACTGTTTACCAGACGAAACCATCGAATATTTGGCTGAGTTATCGGAG
    TGCATGCATGTGACGGTTGAATTGGGCTTGCAGACCACTTATGAAGCAACCTCTGACCTG
    ATTAACCGTGTGCATTCTTATGAATTGGTGGAAACGGTCAAGCGTTTGAGAAAGTATCCC
    AAGATTGAGATTGTTTCCCATTTGATCAATGGTTTGCCTGGTGAAACCCATGAGATGATG
    GTTGAAAATGTCCGCCGTTGTGTCACGGATAACGATATTCAAGGGATTAAACTGCATTTG
    CTCCATCTTATGACAAATACTCGTATGCAACGAGATTACCATGAGGGACGTTTACAATTG
    ATGAGTCAGGACGAATATGTCAGGGTCATCTGTGACCAACTGGAAATTATTCCCAAACAT
    ATCGTCATCCATCGAATTACAGGAGATGCGCCTAGGGATATGCTGATTGGTCCTATGTGG
    AGCCTCAATAAATGGGAAGTCCTCAACAGCATTGAGATGGAGATGCGACGTCGTGGAAGT
    GTTCAAGGATGCAAGGCTGTAAAACAGGAGTTTGAAAATGAAAAGACCACTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    954

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_00994 [new locus tag: SPNA45_RS14060 ]
  • symbol: SPNA45_00994
  • description: putative radical SAM superfamily protein (pseudogene)
  • length: 317
  • theoretical pI: 6.23811
  • theoretical MW: 36744.9
  • GRAVY: -0.450789

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function Enzymes of unknown specificity radical SAM protein, TIGR01212 family (TIGR01212; HMM-score: 336)
    and 10 more
    Genetic information processing Transcription DNA-dependent RNA polymerase radical SAM enzyme/protein acetyltransferase, ELP3 family (TIGR01211; EC 2.3.1.48; HMM-score: 74.6)
    putative heme utilization radical SAM enzyme HutW (TIGR04107; HMM-score: 36.1)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin coproporphyrinogen dehydrogenase HemZ (TIGR03994; EC 1.3.99.22; HMM-score: 27.3)
    Unknown function Enzymes of unknown specificity B12-binding domain/radical SAM domain protein, MJ_1487 family (TIGR04013; HMM-score: 25.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin oxygen-independent coproporphyrinogen III oxidase (TIGR00538; EC 1.3.99.22; HMM-score: 20.5)
    Hypothetical proteins Conserved radical SAM enzyme, TIGR01210 family (TIGR01210; HMM-score: 18.1)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA-i(6)A37 thiotransferase enzyme MiaB (TIGR01574; EC 2.-.-.-; HMM-score: 15.3)
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal protein S12 methylthiotransferase RimO (TIGR01125; EC 2.1.1.-,2.8.1.-; HMM-score: 14.9)
    radical SAM methylthiotransferase, MiaB/RimO family (TIGR00089; EC 2.1.1.-,2.8.1.-; HMM-score: 14.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-polyprenylphenol 6-hydroxylase (TIGR01982; EC 1.14.13.-; HMM-score: 13.1)
  • TheSEED:
  • PFAM:
    no clan defined Radical_SAM_C; Radical_SAM C-terminal domain (PF16199; HMM-score: 89.5)
    and 1 more
    TIM_barrel (CL0036) Radical_SAM; Radical SAM superfamily (PF04055; HMM-score: 46.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9755
    • Cytoplasmic Membrane Score: 0.0041
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0204
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.188908
    • TAT(Tat/SPI): 0.001431
    • LIPO(Sec/SPII): 0.003432
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCM08279 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKVMKSYNTLNDYYRKLFGEKTFKVPIDAGFDCPNRDGTVAHGGCTFCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPDVQKYLVYFQSFTNTHEKVEVIRERYEQAINEPGVVGINIGTRPDCLPDETIEYLAELSECMHVTVELGLQTTYEATSDLINRVHSYELVETVKRLRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTDNDIQGIKLHLLHLMTNTRMQRDYHEGRLQLMSQDEYVRVICDQLEIIPKHIVIHRITGDAPRDMLIGPMWSLNKWEVLNSIEMEMRRRGSVQGCKAVKQEFENEKTT

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPNA45_00994&oldid=157089"