From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 27-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_01251 [new locus tag: SPNA45_RS12445 ]
  • pan locus tag?: PNEUPAN001940000
  • symbol: SPNA45_01251
  • pan gene symbol?: ald
  • synonym:
  • product: putative alanine dehydrogenase 1 (pseudogene)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_01251 [new locus tag: SPNA45_RS12445 ]
  • symbol: SPNA45_01251
  • product: putative alanine dehydrogenase 1 (pseudogene)
  • replicon: chromosome
  • strand: -
  • coordinates: join(1260139..1260465,1260465..1261250)
  • length: 1113
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: HE983624 join(1260139..1260465,1260465..1261250) NCBI
  • BioCyc: see SPNA45_RS12445
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0841 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGTTAATCGGAATCCCAAAAGAAATTAAAAATAACGAAAACCGTGTCGCCCTCACACCT
    GCAGGTGTTCATAGCTTAGTTAGTCGTGGTCATCGTGTCCTTATCGAAACAAATGCTGGT
    CTCAGTTCTGGCTTTACTGATGCTGACTATCAAAAGCAAGGAGCTGAGATTGTCGCTACT
    GCTGGTGAAGCTTGGGCAGCAGAGTTGGTTGTGAAAGTAAAAGAACCTTTAAGTTCTGAA
    TACGGTTACTTGCGCGACGATCTTCTTCTCTTCACCTACTTGCACATGGCCGCTGCTCCA
    GAATTAGCAGATGCTATGTTAGCAGCAAAAACAACAGGAATTGCCTATGAAACTGTTCGT
    GACAATCAAGGACAACTACCGCTCCTCGTTCCTATGAGTGAGGTTGCAGGTCGTATGGCT
    GTTCAAATCGGAGCTCACTTCCTTACTAAGCAAGCTGGTGGCTCTGGTGTTCTACCTGGT
    GGTGTACCAGGTGTTCCAAAAGGAAAAGTAACTATCATCGGTGGTGGTGTCGTCGGTACA
    CATGCTGCCCGCATCGCCCTTGGTCTTGGTGCTCAAGTGACTATTTTAGATATTAGTGCC
    AAGCGTCTCTCAGTTCTAGAAGAAGTCTTTGGAAGTCAAATTCAAACTCTTATGTCTAAT
    TCATTCAACATTGAAGCAAGTGTGAGAGATGCTGATGTGGTGATTGGAGCCATTCTCATC
    CCTGGTGCAAAAGCACCGGAATTGGTGACAGATGAGATGGTCAAACAAATGCGTCCAGGC
    TCTGTAATCGTTGACCTTGCTGTTGACCAAGGTGGCGTTATCGAAACAGCTGACCGTGTG
    ACAACGCACGATGAACCCGTCTATGAAAAACACGGTGTTCTCCACTATGCCGTTGCCAAT
    ATCCCTGGTGCGGTTACCCGCACTTCAACCATCGCCCTAACCAATGTCACTCTTCCTTAT
    ATCGAAGCTTTGGCTGGCAAAGGATTCGCACAAGCAATCTCTGAAGATGAAGGCTTGCGT
    CAAGGTGTGACCACTTATCAAGGTTACTTGACTAGCCTACCAGTTGCTCAAGGACTTAAT
    CGTGACTACACTGATATCAATGATTTAGTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1113

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_01251 [new locus tag: SPNA45_RS12445 ]
  • symbol: SPNA45_01251
  • description: putative alanine dehydrogenase 1 (pseudogene)
  • length: 370
  • theoretical pI: 4.95206
  • theoretical MW: 38899.2
  • GRAVY: 0.158378

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Amino acids and amines alanine dehydrogenase (TIGR00518; EC 1.4.1.1; HMM-score: 546.3)
    and 13 more
    Metabolism Energy metabolism Electron transport NAD(P)(+) transhydrogenase (AB-specific), alpha subunit (TIGR00561; EC 1.6.1.2; HMM-score: 141.3)
    Cellular processes Cellular processes Sporulation and germination dipicolinic acid synthetase, A subunit (TIGR02853; HMM-score: 27)
    dihydrolipoyl dehydrogenase (TIGR01350; EC 1.8.1.4; HMM-score: 21)
    Cellular processes Cellular processes Detoxification mercury(II) reductase (TIGR02053; EC 1.16.1.1; HMM-score: 18.3)
    mycothione reductase (TIGR03452; EC 1.8.1.15; HMM-score: 17.5)
    Metabolism Energy metabolism Electron transport glutathione-disulfide reductase (TIGR01424; EC 1.8.1.7; HMM-score: 17.3)
    6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase (TIGR03201; EC 1.1.1.-; HMM-score: 16.2)
    nucleotide sugar dehydrogenase (TIGR03026; HMM-score: 15.3)
    FAD dependent oxidoreductase TIGR03364 (TIGR03364; HMM-score: 13.8)
    Cellular processes Cellular processes Cell division septum site-determining protein MinD (TIGR01968; HMM-score: 13.3)
    Cellular processes Cellular processes Biosynthesis of natural products 2,3-diaminopropionate biosynthesis protein SbnB (TIGR03944; HMM-score: 13.1)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin siroheme synthase, N-terminal domain (TIGR01470; HMM-score: 12.6)
    Metabolism Energy metabolism Amino acids and amines adenosylhomocysteinase (TIGR00936; EC 3.3.1.1; HMM-score: 11.3)
  • TheSEED:
  • PFAM:
    NADP_Rossmann (CL0063) AlaDh_PNT_C; Alanine dehydrogenase/PNT, C-terminal domain (PF01262; HMM-score: 271.9)
    and 15 more
    Form_Glyc_dh (CL0325) AlaDh_PNT_N; Alanine dehydrogenase/PNT, N-terminal domain (PF05222; HMM-score: 156.6)
    NADP_Rossmann (CL0063) 2-Hacid_dh_C; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain (PF02826; HMM-score: 29.4)
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase (PF00070; HMM-score: 25.1)
    Shikimate_DH; Shikimate / quinate 5-dehydrogenase (PF01488; HMM-score: 22.3)
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase (PF07992; HMM-score: 22.1)
    3HCDH_N; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain (PF02737; HMM-score: 22)
    NAD_binding_7; Putative NAD(P)-binding (PF13241; HMM-score: 18.5)
    NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase (PF03446; HMM-score: 18)
    F420_oxidored; NADP oxidoreductase coenzyme F420-dependent (PF03807; HMM-score: 17.3)
    THF_DHG_CYH_C; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (PF02882; HMM-score: 15.9)
    ADH_zinc_N; Zinc-binding dehydrogenase (PF00107; HMM-score: 14.8)
    TrkA_N; TrkA-N domain (PF02254; HMM-score: 14.5)
    GIDA; Glucose inhibited division protein A (PF01134; HMM-score: 12.4)
    UDPG_MGDP_dh_N; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain (PF03721; HMM-score: 12.4)
    DAO; FAD dependent oxidoreductase (PF01266; HMM-score: 10.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9499
    • Cytoplasmic Membrane Score: 0.0064
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0432
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010703
    • TAT(Tat/SPI): 0.004488
    • LIPO(Sec/SPII): 0.001106
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCM08536 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLSSGFTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPELADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAVQIGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGGGVVGTHAARIALGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAKAPELVTDEMVKQMRPGSVIVDLAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVTRTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYTDINDLV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPNA45_01251&oldid=157346"