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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 27-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_01595 [new locus tag: SPNA45_RS08925 ]
  • pan locus tag?: PNEUPAN001329000
  • symbol: SPNA45_01595
  • pan gene symbol?: lacE_1
  • synonym:
  • product: PTS system, lactose-specific IIB component (EC 2.7.1.69) / PTS system, lactose-specific IIC component (EC 2.7.1.69)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_01595 [new locus tag: SPNA45_RS08925 ]
  • symbol: SPNA45_01595
  • product: PTS system, lactose-specific IIB component (EC 2.7.1.69) / PTS system, lactose-specific IIC component (EC 2.7.1.69)
  • replicon: chromosome
  • strand: -
  • coordinates: 1621293..1621751
  • length: 459
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: HE983624 (1621293..1621751) NCBI
  • BioCyc: see SPNA45_RS08925
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGAAGTCGTCTTGTTTTCATATTGTCTAAATACGAGATATTTACTACAGGTTATAGAT
    ATTGCAAGCTCAAATGATATTATTTTAGAGGAGGATACAAGTGAAATAATGCCTGGTGAG
    ATAGATGTAATAAAAAGTAAGGAGTTGAAAGTACTGGTTCTTTGTGCAGGGTCTGGAACA
    AGTGCGCAATTAGCCAATGCAATTAACGAGGGCACTCAATTAGCAGAAGTTAGAGTGATT
    GCGAATTCAGGAGCGTACGGAGCTCATTATGATATTATGGGTGTTTATGATTTAATTATT
    CTGGCTCCACAAGTTCGGAGTTATTATAGAGAGATGAAGGTGGATGCAGAAAGATTAGGT
    ATTCAGATAGTTGCTACCAGAGGAATGGAATATATTCATTTAACAAAGAGTCCAAGTAAA
    TCCTTACAATTTGTATTGGAGCATTACCAAGCTGTGTAG
    60
    120
    180
    240
    300
    360
    420
    459

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_01595 [new locus tag: SPNA45_RS08925 ]
  • symbol: SPNA45_01595
  • description: PTS system, lactose-specific IIB component (EC 2.7.1.69) / PTS system, lactose-specific IIC component (EC 2.7.1.69)
  • length: 152
  • theoretical pI: 4.6134
  • theoretical MW: 16859.3
  • GRAVY: 0.185526

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, lactose/cellobiose family IIB component (TIGR00853; HMM-score: 93.2)
    Signal transduction Signal transduction PTS PTS system, lactose/cellobiose family IIB component (TIGR00853; HMM-score: 93.2)
  • TheSEED:
  • PFAM:
    Phosphatase (CL0031) PTS_IIB; PTS system, Lactose/Cellobiose specific IIB subunit (PF02302; HMM-score: 40.1)
    and 1 more
    NADP_Rossmann (CL0063) Semialdhyde_dh; Semialdehyde dehydrogenase, NAD binding domain (PF01118; HMM-score: 14.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7405
    • Cytoplasmic Membrane Score: 0.1276
    • Cell wall & surface Score: 0.0007
    • Extracellular Score: 0.1312
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016463
    • TAT(Tat/SPI): 0.002084
    • LIPO(Sec/SPII): 0.002206
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCM08880 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEVVLFSYCLNTRYLLQVIDIASSNDIILEEDTSEIMPGEIDVIKSKELKVLVLCAGSGTSAQLANAINEGTQLAEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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