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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
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ATCC 49619
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ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
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HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 27-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_02083 [new locus tag: SPNA45_RS12950 ]
  • pan locus tag?: PNEUPAN003938000
  • symbol: SPNA45_02083
  • pan gene symbol?: —
  • synonym:
  • product: putative membrane protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_02083 [new locus tag: SPNA45_RS12950 ]
  • symbol: SPNA45_02083
  • product: putative membrane protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2122291..2123727
  • length: 1437
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGTGGGATCCATATGGGCAATTGTCTGACTTACCTGTGGCAGTTGTAAATAATGATAAA
    GAGGCTTCCTATAATGGTAATACTATGGCAATAGGAAAAGACATGGTGTCCAATTTAAAA
    GAAAATAAAACCTTGGATTTTCATTTTGTAGATGAAGAGGAAGGAAAGAAGGGATTGGAA
    GATGGCGATTACTATATGGTAGTGACTTTACCAAGTGATTTATCTGAAAAAACAACTACA
    TTATCCAATCTTCAATCGACAGCAGCTTATCAATCATTGACAAGTGAGCAACAAACTGAG
    ATAAGTGATTCTGTATCTCAAAATTCAACTGATAGTATTCAATCGGCTCAGTCAATTGTA
    GCTTTAGTACAAGGTTTACAGGGAAGTTTAGAAAACTTACAAAATCAATCTTCTAATCTT
    TCGACTTTAAAAAATCAAGCTAATCAAGTATTACCTATTACTTCTACTTCTTTGATAGGA
    TTGTCAAGTGGATTAACAGAGATACAAGGAACTGTTACTAGCAAATTAGTTCCTGCCAGT
    CAGTTGATTGCATCAGGTGTAAACGCATATACTACAGGTGTTGATAAAGTTTCTCAGGGC
    GCAAGTCAACTAAGTGAAAAAAATGCCACCTTGACACAAAAATCTTCTAGATTGACAGCA
    GGAGTTGATAAATTACAATCAGGATCTGGGCAATTAGCAAACAAATCCAGTCAGTTACTT
    TCAGGTGCTTCTTCATTAGAGAATGGAGCTAATAAATTGGCAGATGGATCTGGGAAACTA
    GCAGAAGGTGGAACAAAGTTAACTTCTGGATTGGAAGATTTACAGACAGGACTTGCTTCT
    TTAGGACAAGGACTAGGTAATGCTAGTGATCAACTCAAATCAGTATCAACAGAATCTAAA
    AATGCAGAGATTTTGTCAAATCCACTCAATCTTTCAAAAACAGACAATGATCAAGTTCCT
    GTAAATGGAATCGCAATAGCTCCTTATATGATATCAGTTGCTCTTTTTGTTGCAGCAATA
    TCAACAAATATGATATTTTCGAAATTGCCTTCAGGACGTCATCCAGAGATCCGTTGGGCT
    TGGTTGAAATCTCGATCTGAAATAAATGGTATTATAGCTGTTTTGGCAGGAATTTTGGTA
    TATGGAGGAGTTCATCTTATTGGTTTAACTGCTAATCATGAGATGAGAATATTTATTCTC
    ATCATCCTAACAAGTTTAGTATTCATGTCTATGGTGACCACTTTAACAACGTGGAATAGC
    CGTATAGGAGCTTTCTTCTCACTTATTTTGCTTTTACTACAGTTAGCATCAAGTGCAGGT
    ACTTATCCACTTGCTTTGACAAATGATTTCTTTAGATCTATTAATCCCTGGTTACCAATG
    AGCTATTCAGTTTCGGGATTACGACAAACAATCTCCATCAACAAGTCATTTTCCTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1437

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_02083 [new locus tag: SPNA45_RS12950 ]
  • symbol: SPNA45_02083
  • description: putative membrane protein
  • length: 478
  • theoretical pI: 4.94571
  • theoretical MW: 50729.9
  • GRAVY: -0.0282427

⊟Function[edit | edit source]

  • TIGRFAM:
    YhgE/Pip C-terminal domain (TIGR03062; HMM-score: 192.5)
    and 12 more
    YhgE/Pip N-terminal domain (TIGR03061; HMM-score: 116.8)
    type VII secretion protein EsaA (TIGR03929; HMM-score: 54.1)
    X-X-X-Leu-X-X-Gly heptad repeats (TIGR03057; HMM-score: 31.6)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 23.1)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 23.1)
    Cellular processes Cellular processes Pathogenesis virulence factor Mce family protein (TIGR00996; HMM-score: 17.1)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 15.4)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 15.4)
    SH3 domain protein (TIGR04211; HMM-score: 15.1)
    WXG100 family type VII secretion target (TIGR03930; HMM-score: 8.9)
    helix-rich protein (TIGR04523; HMM-score: 8.7)
    two transmembrane protein (TIGR04527; HMM-score: 5.7)
  • TheSEED:
  • PFAM:
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 38.5)
    DUF3533; Protein of unknown function (DUF3533) (PF12051; HMM-score: 37)
    and 8 more
    ABC2_membrane; ABC-2 type transporter (PF01061; HMM-score: 16)
    Tropomyosin-lke (CL0452) CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels (PF16526; HMM-score: 14.8)
    no clan defined Spc7; Spc7 kinetochore protein (PF08317; HMM-score: 13.4)
    BORCS6; BLOC-1-related complex sub-unit 6 C-terminal helix (PF10157; HMM-score: 12.8)
    UPF0449; Uncharacterised protein family UPF0449 (PF15136; HMM-score: 12.1)
    ATG17_like; Autophagy protein ATG17-like domain (PF04108; HMM-score: 10.9)
    EsxAB (CL0352) WXG100; Proteins of 100 residues with WXG (PF06013; HMM-score: 9.5)
    no clan defined AIP3; Actin interacting protein 3 (PF03915; HMM-score: 7.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0008
    • Cytoplasmic Membrane Score: 0.9305
    • Cell wall & surface Score: 0.0211
    • Extracellular Score: 0.0475
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010315
    • TAT(Tat/SPI): 0.000408
    • LIPO(Sec/SPII): 0.001777
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCM09366 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MWDPYGQLSDLPVAVVNNDKEASYNGNTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNLQSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLSTLKNQANQVLPITSTSLIGLSSGLTEIQGTVTSKLVPASQLIASGVNAYTTGVDKVSQGASQLSEKNATLTQKSSRLTAGVDKLQSGSGQLANKSSQLLSGASSLENGANKLADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVSTESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFSKLPSGRHPEIRWAWLKSRSEINGIIAVLAGILVYGGVHLIGLTANHEMRIFILIILTSLVFMSMVTTLTTWNSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKSFS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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