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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_RS00870 [old locus tag: SPNA45_00144 ]
  • pan locus tag?: PNEUPAN000149000
  • symbol: SPNA45_RS00870
  • pan gene symbol?: xerD
  • synonym:
  • product: tyrosine-type recombinase/integrase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_RS00870 [old locus tag: SPNA45_00144 ]
  • symbol: SPNA45_RS00870
  • product: tyrosine-type recombinase/integrase
  • replicon: chromosome
  • strand: -
  • coordinates: 154021..155154
  • length: 1134
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018594 (154021..155154) NCBI
  • BioCyc: SPNA45_RS00870 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGCAATTAGAAAAGGTAAAGACGGTAATTGGGTAGTTGATATTAGCAACGGTTTTGAC
    CCAATAACACTAAAGCAACGTAGACTTGTCAGAAAGGGCTATAAGACGAAAAAAGAAGCT
    ATTGAAGCAGAACACTACTTACGAAGTGTAGAGTTAAAAGAACGCTTCTATGGGGCTAAA
    ATAACTATCTCCATACTATATGAACTACTTAAGGAAGAAGATAGCATAAATCATCGAAAA
    GCAAGCTATATCAATACACAAGATAATAATTACAACAAACACATCAAAGATTATTTTTCT
    ATGGTCGATAATGTCGGAAAACTAACCTATGAAGACATCTACCAATTTAGAGAACATCTT
    AGGCAAAAAGTAGCTAAAAATTCTGATAAACCGTTAAGCACAAATACTATTAACAAAATC
    ATGATTTTACTCAAAAAAATTTTTGATGTTGGTTTGCGAAAAGGCTATTACTCCTCCAAT
    CCAGCAAAATTGATAAAAAAGTTGCCAATTGAAAAAACAAAAATGCAATTTTGGACAGTC
    AAAGAATTTCAGAAGTTTTTGACACTATTTGAACCCGAAGAATACAATATCAAACTACTC
    TTTACTGTTCTATTCTTTACAGGATTAAGACTTGGGGAAGCTCTTGCCCTAACATGGCAA
    GACATCGACTTTTCAAGTAATACAATTCATATCACGAAATCTGTCTATGTTAATAAAGGA
    GTAACTCATATCAGCACAACAAAAACTAAAGCAGGAACAAGAAGAATTGTTATCAATAAA
    AAATTAAGCCAAGAATTACAAGATTGGGAAAAGCGACAAAAACATCTATTAGAGCAATTT
    ACCAACAATAGCCTAACATTACAAGTGTTTCAAAATAGTCCTATCACAATTACGAAAAAT
    GCTATTGAAAAGCAGTACAAGAAAATCATTGAACGTGATAGCACACTAAAAAAGATACGC
    ATACACGATTTTAGGCACTCACACGCTTCCCTGCTGATTAACCAAGGGGAAGATTATCTA
    GTTGTAAAAGAGCGACTAGGACATGCTTCTATAACAACCACGATTGATACCTACTCTCAC
    TTGTACCCAAGTAAGCAAAAGGATTTAGCTGATAAACTAGATGATTTACTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1134

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_RS00870 [old locus tag: SPNA45_00144 ]
  • symbol: SPNA45_RS00870
  • description: tyrosine-type recombinase/integrase
  • length: 377
  • theoretical pI: 10.2371
  • theoretical MW: 44197.7
  • GRAVY: -0.566048

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 99.1)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 90.1)
    and 2 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 66.7)
    Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 66.7)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 90.4)
    and 9 more
    l-integrase_N (CL0469) Phage_int_SAM_5; Phage integrase SAM-like domain (PF13102; HMM-score: 26.8)
    MBD-like (CL0081) Arm-DNA-bind_4; Arm DNA-binding domain (PF14657; HMM-score: 25.6)
    l-integrase_N (CL0469) Phage_int_SAM_1; Phage integrase, N-terminal SAM-like domain (PF02899; HMM-score: 15.7)
    DNA-mend (CL0382) Phage_integr_3; Archaeal phage integrase (PF16795; HMM-score: 15)
    no clan defined DUF5633; Family of unknown function (DUF5633) (PF18656; HMM-score: 12.1)
    NADP_Rossmann (CL0063) Methyltransf_9; Protein of unknown function (DUF1698) (PF08003; HMM-score: 10.7)
    l-integrase_N (CL0469) Phage_int_SAM_3; Phage integrase, N-terminal SAM-like domain (PF14659; HMM-score: 9.8)
    no clan defined DUF1104; Protein of unknown function (DUF1104) (PF06518; HMM-score: 9.5)
    HTH (CL0123) DpnI_C; Dam-replacing HTH domain (PF17726; HMM-score: 8.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9794
    • Cytoplasmic Membrane Score: 0.0032
    • Cell wall & surface Score: 0.0084
    • Extracellular Score: 0.009
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00299
    • TAT(Tat/SPI): 0.000167
    • LIPO(Sec/SPII): 0.000347
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001007701 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAEHYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMVDNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSNPAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALTWQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHLLEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLINQGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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