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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_RS01005 [old locus tag: SPNA45_00169 ]
  • pan locus tag?: PNEUPAN003813000
  • symbol: SPNA45_RS01005
  • pan gene symbol?: comGB
  • synonym:
  • product: type II secretion system F family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_RS01005 [old locus tag: SPNA45_00169 ]
  • symbol: SPNA45_RS01005
  • product: type II secretion system F family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 177998..179014
  • length: 1017
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018594 (177998..179014) NCBI
  • BioCyc: SPNA45_RS01005 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1862 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAA
    AATATCATCACCCTATTTAACAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATC
    TCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTGTGACCCAGATGCGTACAGGC
    TTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
    GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATA
    GAAGAATATCTAGACAATCTGGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTAT
    CCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGGGGCTACGGAATTACCTGCTC
    CCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
    CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGA
    AGTTCTAAGATGAGTGTCTTTTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTG
    CAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGAATATGATTTCACAGGGAATG
    GAGTTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
    GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACC
    TATCCTTTCTTTAGGAAGGAATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAG
    CTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGGAAGCCTTTTTTACCCGAGTC
    AACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATTTTTGTGGCACTGATTATCGTT
    TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1017

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_RS01005 [old locus tag: SPNA45_00169 ]
  • symbol: SPNA45_RS01005
  • description: type II secretion system F family protein
  • length: 338
  • theoretical pI: 9.62597
  • theoretical MW: 38482.2
  • GRAVY: 0.288757

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type II secretion system protein F (TIGR02120; HMM-score: 83.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined T2SSF; Type II secretion system (T2SS), protein F (PF00482; HMM-score: 97.1)
    and 2 more
    Cytochrome-c (CL0318) Cytochrome-c551; Photosystem P840 reaction-centre cytochrome c-551 (PF10643; HMM-score: 10.6)
    no clan defined DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 6.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007182
    • TAT(Tat/SPI): 0.00068
    • LIPO(Sec/SPII): 0.000959
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_074017570 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIFLGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNMEVNF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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