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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_RS06495 [old locus tag: SPNA45_01156 ]
  • pan locus tag?: PNEUPAN001794000
  • symbol: SPNA45_RS06495
  • pan gene symbol?: cdd-1
  • synonym:
  • product: cytidine deaminase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_RS06495 [old locus tag: SPNA45_01156 ]
  • symbol: SPNA45_RS06495
  • product: cytidine deaminase
  • replicon: chromosome
  • strand: +
  • coordinates: 1151586..1151975
  • length: 390
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018594 (1151586..1151975) NCBI
  • BioCyc: SPNA45_RS06495 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0738 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGGCGACTACTGAGTTGATTGAACTGGCAATTGAAACCAGCAAACATGCCTATGTCCCC
    TATTCTCACTTTCCTATCGGAGCAGTTTTAGTAGCCAAAGACGGAAGTGTTTACACGGGA
    GTGAATATCGAAAATGCTAGCTATCCTTTGACCAATTGCGGTGAGAGAACAGCTATTTTT
    AAGGCTATATCTGAAGGCCAAAGAGAATTTTCAGAATTGATTGTCTATGGTCAAACTGAA
    AAACCGATCTCGCCATGTGGTGCTTGTCGCCAAGTGATGGCTGAATTTTTTGAACAAGAT
    CTAAAAGTGACCTTAGTCGCAAAAGATAAATCGACGGTCGAGATGACGGTCGGGGAATTA
    CTTCCATACTCTTTTACAGACTTAAACTAG
    60
    120
    180
    240
    300
    360
    390

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_RS06495 [old locus tag: SPNA45_01156 ]
  • symbol: SPNA45_RS06495
  • description: cytidine deaminase
  • length: 129
  • theoretical pI: 4.44985
  • theoretical MW: 14175.1
  • GRAVY: -0.00155039

⊟Function[edit | edit source]

  • reaction:
    EC 3.5.4.5?  ExPASy
    Cytidine deaminase Cytidine + H2O = uridine + NH3 2'-deoxycytidine + H2O = 2'-deoxyuridine + NH3
  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides cytidine deaminase (TIGR01354; EC 3.5.4.5; HMM-score: 152.1)
    and 2 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides cytidine deaminase (TIGR01355; EC 3.5.4.5; HMM-score: 57.6)
    putative CRISPR-associated protein, APE2256 family (TIGR02619; HMM-score: 12.4)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    CDA (CL0109) dCMP_cyt_deam_1; Cytidine and deoxycytidylate deaminase zinc-binding region (PF00383; HMM-score: 62.8)
    and 7 more
    dCMP_cyt_deam_2; Cytidine and deoxycytidylate deaminase zinc-binding region (PF08211; HMM-score: 37.7)
    LmjF365940-deam; A distinct subfamily of CDD/CDA-like deaminases (PF14421; HMM-score: 15.8)
    SNAD4; Secreted Novel AID/APOBEC-like Deaminase 4 (PF18750; HMM-score: 15.4)
    no clan defined DUF6510; Family of unknown function (DUF6510) (PF20120; HMM-score: 14.8)
    CDA (CL0109) APOBEC4_like; APOBEC4-like -AID/APOBEC-deaminase (PF18774; HMM-score: 12.4)
    APOBEC1; APOBEC1 (PF18769; HMM-score: 12.3)
    NAD1; Novel AID APOBEC clade 1 (PF18778; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9836
    • Cytoplasmic Membrane Score: 0.0035
    • Cell wall & surface Score: 0.0025
    • Extracellular Score: 0.0104
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013318
    • TAT(Tat/SPI): 0.000865
    • LIPO(Sec/SPII): 0.001637
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000246086 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIENASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLKVTLVAKDKSTVEMTVGELLPYSFTDLN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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