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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-APR-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu15
  • locus tag: SPNHU15_RS07675 [old locus tag: SPNHU15_01616 ]
  • pan locus tag?: PNEUPAN002973000
  • symbol: SPNHU15_RS07675
  • pan gene symbol?: gatD
  • synonym:
  • product: type 1 glutamine amidotransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU15_RS07675 [old locus tag: SPNHU15_01616 ]
  • symbol: SPNHU15_RS07675
  • product: type 1 glutamine amidotransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 1527077..1527859
  • length: 783
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP020551 (1527077..1527859) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1417 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGGTTTATACTTCACTTTCCTCAAAAGATGGCAATTACCCCTATCAGCTCAACATTGCC
    CACCTCTACGGAAATCTCATGAATACCTACGGGGACAATGGAAACATCCTCATGCTCAAG
    TATGTGGCTGAAAAACTGGGAGCCCATGTGATCGTTGACATCGTTTCTCTCCATGATGAC
    TTTGATGAAAATCACTACGACATCGCCTTTTTCGGTGGTGGTCAAGACTTTGAACAAAGT
    ATCATTGCAGACGACCTACCTGCTAAAAAAGAGAGCATTGACAACTACATCCAAAACGAC
    GGTGTAGTTCTGGCTATCTGCGGTGGTTTCCAACTATTGGGTCAATATTATGTTGAAGCT
    TCAGGAAAACGTATCGAAGGGCTAGGGGTCATGGGACACTACACGCTCAACCAGACCAAT
    AACCGTTTTATCGGTGACATCAAGATTCACAATGAAGATTTCGATGAAACCTACTATGGA
    TTTGAAAATCACCAAGGTCGTACCTTCCTCTCTGATGACCAAAAACCGCTGGGACAGGTT
    GTCTATGGAAATGGAAACAACGAAGAAAAGGTCGGTGAAGGGGTTCATTATAAGAATGTC
    TTTGGTTCCTACTTCCACGGGCCTATCCTCTCTCGTAATGCCAATCTGGCTTATCGCCTA
    GTTACTACTGCCCTCAAGAAGAAATATGGTCAGGACATCCAACTCCCTGCCTATGAGGAC
    ATTCTCAGCCAAGAAATCGCTGAAGAGTACAGTGACGTCAAAAGCAAGGCTGACTTTTCT
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    783

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNHU15_RS07675 [old locus tag: SPNHU15_01616 ]
  • symbol: SPNHU15_RS07675
  • description: type 1 glutamine amidotransferase
  • length: 260
  • theoretical pI: 4.55216
  • theoretical MW: 29205.2
  • GRAVY: -0.445

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin cobyric acid synthase CobQ (TIGR00313; EC 6.3.5.10; HMM-score: 58.1)
    and 3 more
    Metabolism Amino acid biosynthesis Histidine family imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (TIGR01855; EC 2.4.2.-; HMM-score: 19.5)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis phosphoribosylformylglycinamidine synthase I (TIGR01737; EC 6.3.5.3; HMM-score: 15.6)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides intracellular protease, PfpI family (TIGR01382; HMM-score: 14.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Glutaminase_I (CL0014) GATase_3; CobB/CobQ-like glutamine amidotransferase domain (PF07685; HMM-score: 158.1)
    and 4 more
    DJ-1_PfpI; DJ-1/PfpI family (PF01965; HMM-score: 15.7)
    Acetyltrans (CL0257) Acetyltransf_18; Acetyltransferase (GNAT) domain (PF18014; HMM-score: 15.1)
    Glutaminase_I (CL0014) GATase; Glutamine amidotransferase class-I (PF00117; HMM-score: 14.6)
    GATase_5; CobB/CobQ-like glutamine amidotransferase domain (PF13507; HMM-score: 14.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006857
    • TAT(Tat/SPI): 0.000085
    • LIPO(Sec/SPII): 0.000438
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000263189 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAEKLGAHVIVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGVVLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYGFENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAYRLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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