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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-APR-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu17
  • locus tag: SPNHU17_01866 [new locus tag: SPNHU17_RS08730 ]
  • pan locus tag?: PNEUPAN003345000
  • symbol: SPNHU17_01866
  • pan gene symbol?: ABC-SBP_8
  • synonym:
  • product: ABC transporter, substrate-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU17_01866 [new locus tag: SPNHU17_RS08730 ]
  • symbol: SPNHU17_01866
  • product: ABC transporter, substrate-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1735927..1736994
  • length: 1068
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAAAAAAATGAAAGTTTGGTCTACTGTACTTGCAACGGGAGTTGCTCTTACTACACTT
    GCTGCTTGCTCTGGAGGTTCAAATTCTACGACTGCTTCTTCATCTGAAGAAAAAGCTGAT
    AAAAGTCAAGAATTAGTTATCTATTCGAACTCAGTCTCAAATGGTCGTGGTGATTGGTTA
    ACTGCTAAAGCAAAAGAAGCTGGTTTTAATATAAAAATGGTTGATATCGCTGGCGCTCAA
    TTAGCAGACCGTGTTATTGCTGAGAAGAATAATGCAGTTGCAGATATGGTATTTGGAATT
    GGTGCTGTTGACTCAAATAAAATTAGAGATCAAAAATTACTAGTACAGTACAAGCCTAAA
    TGGTTAGATAAAATTGATCAATCTTTATCAGATAAAGATAATTATTATAATCCTGTGATT
    GTTCAACCATTAGTTTTAATTGGGGCGCCTGATGTAAAAGAAATGCCTAAAGATTGGACT
    GAATTAGGTAGTAAGTATAAAGGTAAATATTCAATTTATGGTCTTCAAGGTGGTACAGGA
    CGGGCAATTCTAGCAAGTATCTTAGTTCGTTACCTTGATGAAAAAGGAGATTTAGGCGTA
    TCAGAAAAAGGATGGGAAGTTGCAAAAGAATACTTTGCAAATGCCTATACTCTTCAAAAA
    GGTGAAAGCTCAGTTGTTAAAGCGTTAGATAAAGAAAGCCCAATTCAATACGGTATGATC
    TGGGGTTCTGGATCGTTAATTGGACAAAAAGAACAAAATGTTGAATTCAAAGTTATGACT
    CCTGAGATTGGTGTACCATTTGTAACTGAACAAACTATGGTTTTAAGCACTAGTAAAAAA
    CAAGCGTTAGCTAAAGAATTTATTGATTGGTTTGGTCAATCAGAAATTCAAGTAGAATAT
    AGTAAAAAATTTGGATCTATTCCTGCAAATAAAGATGCCCTAAAAGAGTTACCTGAAGAT
    ACGAAAAAATTTGTTGATCAAGTGAAACCACAAAATATTGACTGGGAAGCTGTTGGAAAG
    CATTTGGATGAATGGGTAGAAAAAGCTGAATTAGAATACGTACAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1068

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNHU17_01866 [new locus tag: SPNHU17_RS08730 ]
  • symbol: SPNHU17_01866
  • description: ABC transporter, substrate-binding protein
  • length: 355
  • theoretical pI: 5.20185
  • theoretical MW: 39218.4
  • GRAVY: -0.367606

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein (TIGR03261; HMM-score: 53.9)
    and 6 more
    2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein (TIGR03227; HMM-score: 38.7)
    Metabolism Transport and binding proteins Other ABC transporter periplasmic binding protein, thiB subfamily (TIGR01254; HMM-score: 19.8)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids carbohydrate ABC transporter substrate-binding protein, CPR_0540 family (TIGR03850; HMM-score: 15)
    Cell structure Cell envelope Other rare lipoprotein A (TIGR00413; HMM-score: 14)
    Cellular processes Cellular processes Biosynthesis of natural products nif11-like leader peptide domain (TIGR03798; HMM-score: 12.5)
    Unknown function Enzymes of unknown specificity HAD hydrolase, TIGR01457 family (TIGR01457; HMM-score: 12.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    PBP (CL0177) SBP_bac_6; Bacterial extracellular solute-binding protein (PF13343; HMM-score: 81.7)
    and 2 more
    SBP_bac_8; Bacterial extracellular solute-binding protein (PF13416; HMM-score: 57.6)
    SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 30.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0005
    • Cytoplasmic Membrane Score: 0.8246
    • Cell wall & surface Score: 0.0317
    • Extracellular Score: 0.1432
  • SignalP: Signal peptide LIPO(Sec/SPII) length 22 aa
    • SP(Sec/SPI): 0.002134
    • TAT(Tat/SPI): 0.000183
    • LIPO(Sec/SPII): 0.997505
    • Cleavage Site: CS pos: 22-23. LAA-CS. Pr: 0.9981
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ARD35410 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQELVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGAVDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWTELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTLQKGESSVVKALDKESPIQYGMIWGSGSLIGQKEQNVEFKVMTPEIGVPFVTEQTMVLSTSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNIDWEAVGKHLDEWVEKAELEYVQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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