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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 07-MAR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu17
  • locus tag: SPNHU17_RS02455 [old locus tag: SPNHU17_00527 ]
  • pan locus tag?: PNEUPAN001320000
  • symbol: rrgC
  • pan gene symbol?: rrgC
  • synonym:
  • product: PI-1 pilus minor pilin RrgC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU17_RS02455 [old locus tag: SPNHU17_00527 ]
  • symbol: rrgC
  • product: PI-1 pilus minor pilin RrgC
  • replicon: chromosome
  • strand: +
  • coordinates: 481057..482238
  • length: 1182
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP020549 (481057..482238) NCBI
  • BioCyc: SPNHU17_RS02455 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGATTAGTCGTATCTTCTTTGTTATGGCTCTGTGTTTTTCTCTTGTATGGGGTGCACAT
    GCAGTCCAAGCGCAAGAAGATCACACGTTGGTCTTGCAATTGGAGAACTATCAGGAGGTG
    GTTAGTCAATTGCCATCTCGTGATGGTCATCGGTTGCAAGTATGGAAGTTGGATGATTCG
    TATTCCTATGATGATCGGGTGCAAATTGTAAGAGACTTGCATTCGTGGGATGAGAATAAA
    CTTTCTTCTTTCAAAAAGACTTCGTTTGAGATGACCTTCCTTGAGAATCAGATTGAAGTA
    TCTCATATTCCAAATGGTCTTTACTATGTTCGCTCTATTATCCAGACGGATGCGGTTTCT
    TATCCAGCTGAATTTCTTTTTGAAATGACAGATCAAACGGTAGAGCCTTTGGTCATTGTA
    GCGAAAAAAACAGATACAATGACAACAAAGGTGAAGCTGATAAAGGTGGATCAAGACCAC
    AATCGCTTGGAGGGTGTCGGCTTTAAATTGGTATCAGTAGCAAGAGATGGTTCTGAAAAA
    GAGGTTCCCTTGATTGGAGAATACCGTTACAGTTCTTCTGGTCAAGTAGGGAGAACTCTC
    TATACTGATAAAAATGGAGAGATTTTTGTGACAAATCTTCCTCTTGGGAACTATCGTTTC
    AAGGAGGTGGAGCCACTGGCAGGCTATGCTGTTACGACGCTGGATACGGATGTCCAGCTG
    GTAGATCATCAGCTGGTGACGATTACGGTTGTCAATCAGAAATTACCACGTGGCAATGTT
    GACTTTATGAAGGTGGATGGTCGGACCAATACCTCTCTTCAAGGGGCAATGTTCAAAGTC
    ATGAAAGAAGAAAGCGGACACTATACTCCTGTTCTTCAAAATGGTAAGGAAGTAGTTGTA
    ACATCAGGGAAAGATGGTCGTTTCCGAGTGGAAGGTCTAGAGTATGGGACATACTATTTA
    TGGGAGCTCCAAGCTCCAACTGGTTATGTTCAATTAACATCGCCTGTTTCCTTTACAATC
    GGGAAAGATACTCGTAAGGAACTGGTAACAGTGGTTAAAAATAACAAGCGACCACGGATT
    GATGTGCCAGATACAGGGGAAGAAACCTTGTATATCTTGATGCTTGTTGCCATTTTGTTG
    TTTGGTAGTGGTTATTATCTTACGAAAAAACCAAATAACTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1182

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNHU17_RS02455 [old locus tag: SPNHU17_00527 ]
  • symbol: RrgC
  • description: PI-1 pilus minor pilin RrgC
  • length: 393
  • theoretical pI: 5.90813
  • theoretical MW: 44669.6
  • GRAVY: -0.271247

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 16.9)
  • TheSEED: data available for Hungary19A-6, TIGR4
  • PFAM:
    Transthyretin (CL0287) SpaA; Prealbumin-like fold domain (PF17802; HMM-score: 112.2)
    and 8 more
    CarboxypepD_reg; Carboxypeptidase regulatory-like domain (PF13620; HMM-score: 26.4)
    SdrD_B; SdrD B-like domain (PF17210; HMM-score: 20.1)
    E-set (CL0159) Y_Y_Y; Y_Y_Y domain (PF07495; HMM-score: 16.1)
    Transthyretin (CL0287) CarbopepD_reg_2; CarboxypepD_reg-like domain (PF13715; HMM-score: 13.8)
    EMC7_beta-sandw; ER membrane protein complex subunit 7, beta-sandwich domain (PF09430; HMM-score: 13.6)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 12.8)
    CDA (CL0109) LpxI_C; LpxI C-terminal domain (PF06230; HMM-score: 12.6)
    E-set (CL0159) Por_Secre_tail; Secretion system C-terminal sorting domain (PF18962; HMM-score: 12)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0016
    • Cytoplasmic Membrane Score: 0.6576
    • Cell wall & surface Score: 0.331
    • Extracellular Score: 0.0098
  • SignalP: Signal peptide SP(Sec/SPI) length 24 aa
    • SP(Sec/SPI): 0.989216
    • TAT(Tat/SPI): 0.005964
    • LIPO(Sec/SPII): 0.002098
    • Cleavage Site: CS pos: 24-25. VQA-QE. Pr: 0.9326
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_176717987 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQLPSRDGHRLQVWKLDDSYSYDDRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSHIPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKTDTMTTKVKLIKVDQDHNRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIFVTNLPLGNYRFKEVEPLAGYAVTTLDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGAMFKVMKEESGHYTPVLQNGKEVVVTSGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTSPVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKPNN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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