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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 07-MAR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu17
  • locus tag: SPNHU17_RS04540 [old locus tag: SPNHU17_00988 ]
  • pan locus tag?: PNEUPAN001917000
  • symbol: yabA
  • pan gene symbol?: yabA
  • synonym:
  • product: DNA replication initiation control protein YabA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU17_RS04540 [old locus tag: SPNHU17_00988 ]
  • symbol: yabA
  • product: DNA replication initiation control protein YabA
  • replicon: chromosome
  • strand: +
  • coordinates: 912919..913236
  • length: 318
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP020549 (912919..913236) NCBI
  • BioCyc: SPNHU17_RS04540 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0827 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGGACAAAAAAGAATTATTTGACGCGCTGGATGATTTTTCCCAACAATTATTGGTAACT
    TTAGCCGATGTGGAAGCCATCAAGAAAAATCTCAAGAGCTTGGTAGAAGAAAATACAGCT
    CTTCGCTTGGAAAATAGTAAGTTGCGAGAACGCTTGGGTGAGGTGGAAGCAGACGCTCCC
    GTCAAGGCCAAGCATGTTCGCGAAAGTGTCCGTCGTATTTACCGTGATGGATTTCACGTA
    TGTAATGATTTTTATGGACAACGTCGAGATCAGGACGAAGAATGTATGTTCTGTGATGAG
    TTGTTATACAGGGAGTAA
    60
    120
    180
    240
    300
    318

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNHU17_RS04540 [old locus tag: SPNHU17_00988 ]
  • symbol: YabA
  • description: DNA replication initiation control protein YabA
  • length: 105
  • theoretical pI: 4.71978
  • theoretical MW: 12396.9
  • GRAVY: -0.72381

⊟Function[edit | edit source]

  • TIGRFAM:
    SH3 domain protein (TIGR04211; HMM-score: 14)
    Signal transduction Signal transduction PTS PTS IIA-like nitrogen-regulatory protein PtsN (TIGR01419; HMM-score: 12.8)
    Genetic information processing Mobile and extrachromosomal element functions Plasmid functions integrating conjugative element protein, PFL_4705 family (TIGR03752; HMM-score: 12.3)
    two transmembrane protein (TIGR04527; HMM-score: 11.7)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined YabA; Initiation control protein YabA (PF06156; HMM-score: 105)
    and 7 more
    HAP1_N; HAP1 N-terminal conserved region (PF04849; HMM-score: 18.2)
    DegS; Sensor protein DegS (PF05384; HMM-score: 16.9)
    TSC22; TSC-22/dip/bun family (PF01166; HMM-score: 16.3)
    NYD-SP28_assoc; Sperm tail C-terminal domain (PF14775; HMM-score: 14.8)
    DUF4201; Domain of unknown function (DUF4201) (PF13870; HMM-score: 14.6)
    NEMO; NF-kappa-B essential modulator NEMO (PF11577; HMM-score: 14.4)
    HMMR_C; Hyaluronan mediated motility receptor C-terminal (PF15908; HMM-score: 13.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9917
    • Cytoplasmic Membrane Score: 0.0033
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0048
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.0025
    • TAT(Tat/SPI): 0.000453
    • LIPO(Sec/SPII): 0.000334
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_208912223 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLENSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRRDQDEECMFCDELLYRE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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