PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 07-MAR-2025

⊟Summary

• organism: Streptococcus pneumoniae Hu17
• locus tag: SPNHU17_RS06210 [old locus tag: SPNHU17_01333 ]
• pan locus tag^?: PNEUPAN002558000
• symbol: SPNHU17_RS06210
• pan gene symbol^?: tet(M)
• synonym:
• product: elongation factor G

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPNHU17_RS06210 [old locus tag: SPNHU17_01333 ]
• symbol: SPNHU17_RS06210
• product: elongation factor G
• replicon: chromosome
• strand: -
• coordinates: 1244686..>1245679
• length: 994
• essential: unknown

⊟Accession numbers

• Location: NZ_CP020549 (1244686..>1245679) NCBI
• BioCyc: SPNHU17_RS06210 BioCyc
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  
  TTCCGGGGAAATTGTTATTTTGCAGAATGAGTTTTTGAAGTTAAATAGTGTTCTTGGAGA
  TACAAAGCTATTGCCACAGAGAGAGAGAATTGAAAATCCCCTCCCTCTGCTGCAAACGAC
  TGTTGAACCGAGCAAACCTCAACAAAGGGAAATGTTACTTGATGCACTTTTAGAAATCTC
  CGACAGTGACCCGCTTCTGCGATATTATGTGGATTCTGCGACACATGAAATCATACTTTC
  TTTCTTAGGGAAAGTACAAATGGAAGTGACTTGTGCTCTGCTGCAAGAAAAGTATCATGT
  GGAGATAGAAATAAAAGAGCCTACAGTCATTTATATGGAAAGACCGTTAAAAAAAGCAGA
  GTATACCATTCACATCGAAGTTCCACCGAATCCTTTCTGGGCTTCCATTGGTCTATCTGT
  AGCACCGCTTCCATTAGGGAGCGGAGTACAGTATGAGAGCTCGGTTTCTCTTGGATACTT
  AAATCAATCGTTTCAAAATGCAGTTATGGAGGGGATACGCTATGGCTGTGAACAAGGATT
  GTATGGTTGGAATGTGACGGACTGTAAAATCTGTTTTAAGTATGGCTTATACTATAGCCC
  TGTTAGTACCCCAGCAGATTTTCGGATGCTTGCTCCTATTGTATTGGAACAAGTCTTAAA
  AAAAGCTGGAACAGAATTGTTAGAGCCATATCTTAGTTTTAAAATTTATGCGCCACAGGA
  ATATCTTTCACGAGCATACAACGATGCTCCTAAATATTGTGCGAACATCGTAGACACTCA
  ATTGAAAAATAATGAGGTCATTCTTAGTGGAGAAATCCCTGCTCGGTGTATTCAAGAATA
  TCGTAGTGATTTAACTTTCTTTACAAATGGACGTAGTGTTTGTTTAACAGAGTTAAAAGG
  GTACCATGTTACTACCGGTGAACCTGTTTGCCAGCCCCGTCGTCCAAATAGTCGGATAGA
  TAAAGTACGATATATGTTCAATAAAATAACTTAG
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  994
  

⊟Protein

⊟General

• locus tag: SPNHU17_RS06210 [old locus tag: SPNHU17_01333 ]
• symbol: SPNHU17_RS06210
• description: elongation factor G
• length: 330
• theoretical pI: 5.27301
• theoretical MW: 37552
• GRAVY: -0.19

⊟Function

• TIGRFAM:
  Genetic information processing Protein synthesis Translation factors translation elongation factor G (TIGR00484; HMM-score: 85.9)
  and 6 more
  Genetic information processing Protein synthesis Translation factors translation elongation factor aEF-2 (TIGR00490; HMM-score: 44.5)
  Unknown function General elongation factor 4 (TIGR01393; EC 3.6.5.-; HMM-score: 17.8)
  Cellular processes Cellular processes Adaptations to atypical conditions GTP-binding protein TypA/BipA (TIGR01394; HMM-score: 14.4)
  Genetic information processing Protein synthesis Translation factors GTP-binding protein TypA/BipA (TIGR01394; HMM-score: 14.4)
  Signal transduction Regulatory functions Other GTP-binding protein TypA/BipA (TIGR01394; HMM-score: 14.4)
  Genetic information processing Protein synthesis Translation factors peptide chain release factor 3 (TIGR00503; HMM-score: 10.1)
• TheSEED:
• PFAM:
  S5 (CL0329) EFG_IV; Elongation factor G, domain IV (PF03764; HMM-score: 84.6)
  and 4 more
  EF-G_C (CL0437) EFG_C; Elongation factor G C-terminus (PF00679; HMM-score: 60.8)
  EFG_III; Elongation Factor G, domain III (PF14492; HMM-score: 50.8)
  RF3_C; Class II release factor RF3, C-terminal domain (PF16658; HMM-score: 16.9)
  DPBB (CL0199) Cerato-platanin; Cerato-platanin (PF07249; HMM-score: 13)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 9.97
  • Cytoplasmic Membrane Score: 0
  • Cellwall Score: 0.01
  • Extracellular Score: 0.02
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9583
  • Cytoplasmic Membrane Score: 0.0151
  • Cell wall & surface Score: 0.0001
  • Extracellular Score: 0.0266
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002944
  • TAT(Tat/SPI): 0.00017
  • LIPO(Sec/SPII): 0.000578
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_208912128 NCBI
• UniProt:

⊟Protein sequence

• SGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVAPLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications