PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 25-AUG-2021

⊟Summary

• organism: Streptococcus pneumoniae Hu17
• locus tag: SPNHU17_RS09735 [old locus tag: SPNHU17_02070 ]
• pan locus tag^?: PNEUPAN003617000
• symbol: SPNHU17_RS09735
• pan gene symbol^?: eloR
• synonym:
• product: cell elongation regulator EloR

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPNHU17_RS09735 [old locus tag: SPNHU17_02070 ]
• symbol: SPNHU17_RS09735
• product: cell elongation regulator EloR
• replicon: chromosome
• strand: -
• coordinates: 1928425..1929411
• length: 987
• essential: unknown

⊟Accession numbers

• Location: NZ_CP020549 (1928425..1929411) NCBI
• BioCyc: SPNHU17_RS09735 BioCyc
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_1849 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  
  ATGGTAGTATTTACAGGTTCAACTGTTGAAGAAGCAATCCAGAAAGGATTGAAAGAATTA
  GATATTCCAAGAATGAAGGCTCATATCAAAGTCATTTCTAGGGAGAAGAAAGGCTTTCTT
  GGTCTATTTGGTAAAAAACCAGCCCAAGTGGATATTGAAACGATTAGTGAAACGACTGTT
  GTCAAAGCAAATCAACAGGTAGTAAAAGGCGTTCCGAAAAAAATCAATGATTTGAACGAG
  CCTGTGAAGACGGTTAGTGAAGAAACCGTTGACCTTGGTCATGTGGTTGATGCTATTAAA
  AAAATAGAGGAAGAAGGTCAAGGCATTTCTGATGAAGTCAAGGCTGAAATCTTAAAACAT
  GAAAGACATGCCAGCACTATCTTAGAAGAAACTGGTCACATTGAGATTTTAAATGAACTT
  CAAATCGAGGAAGCGATGAGGGAAGAAGCAGGCGCTGATGACCTTGAAACTGAGCAAGAC
  CAAGCTGAAAGTCAAGAACTAGAAGACTTGGGCTTGAAAGTTGAAACGAACTTTGATATT
  GAACAAGTAGCTACGGAAGTAATGGCTTATGTTCAAACGATTATTGATGACATGGATGTT
  GAGGCTACACTTTCAAATGATTATAACCGTCGTAGCATCAATTTGCAAATTGATACTAAC
  GAACCAGGTCGTATTATCGGCTACCATGGTAAAGTCTTGAAGGCCTTGCAACTGTTGGCT
  CAAAATTATCTTTACAACTGCTATTCAAGAACCTTCTATATCACTATTAATGTCAATGAT
  TATGTTGAACACCGTGCAGAAGTCTTGCAGACCTATGCGCAAAAATTGGCGATTCGTGTT
  TTAGAAGAAGGACGTAGTCATCAAACAGATCCAATGTCGAATAGTGAACGCAAGATTATC
  CACCGTATTATTTCACGTATGGATGGCGTGACCAGTTACTCTGAAGGTGATGAGCCAAAT
  CGCTATGTCGTTGTAGATACAGAATAA
  60
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  420
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  540
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  960
  987
  

⊟Protein

⊟General

• locus tag: SPNHU17_RS09735 [old locus tag: SPNHU17_02070 ]
• symbol: SPNHU17_RS09735
• description: cell elongation regulator EloR
• length: 328
• theoretical pI: 4.49681
• theoretical MW: 37112.5
• GRAVY: -0.486585

⊟Function

• TIGRFAM:
  Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiamine biosynthesis protein ThiS (TIGR01683; HMM-score: 8.7)
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  no clan defined Jag_N; Jag N-terminus (PF14804; HMM-score: 71)
  R3H; R3H domain (PF01424; HMM-score: 59.7)
  and 5 more
  KH (CL0007) KH_4; KH domain (PF13083; HMM-score: 53.9)
  KH_2; KH domain (PF07650; HMM-score: 16.4)
  Ubiquitin (CL0072) Lambda_tail_I; Bacteriophage lambda tail assembly protein I (PF06805; HMM-score: 15.4)
  no clan defined Cauli_AT; Aphid transmission protein (PF03233; HMM-score: 7.4)
  DUF4758; Putative sperm flagellar membrane protein (PF15950; HMM-score: 7.1)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002925
  • TAT(Tat/SPI): 0.000518
  • LIPO(Sec/SPII): 0.000544
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_000260027 NCBI
• UniProt:

⊟Protein sequence

• MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFGKKPAQVDIETISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKIEEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQDQAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQIDTNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKLAIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V: SPV_1849 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications

Gro Anita Stamsås, Daniel Straume, Anja Ruud Winther, Morten Kjos, Cyril Alexander Frantzen, Leiv Sigve Håvarstein
Identification of EloR (Spr1851) as a regulator of cell elongation in Streptococcus pneumoniae.
Mol Microbiol: 2017, 105(6);954-967
[PubMed:28710862] [WorldCat.org] [DOI] (I p)