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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-FEB-2016

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV200
  • locus tag: SPNINV200_01410 [new locus tag: SPNINV200_RS00770 ]
  • pan locus tag?: PNEUPAN000832000
  • symbol: SPNINV200_01410
  • pan gene symbol?: —
  • synonym:
  • product: Lantibiotic biosynthesis protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNINV200_01410 [new locus tag: SPNINV200_RS00770 ]
  • symbol: SPNINV200_01410
  • product: Lantibiotic biosynthesis protein
  • replicon: chromosome
  • strand: +
  • coordinates: join(143848..146760,146747..148024)
  • length: 4191
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: FQ312029 join(143848..146760,146747..148024) NCBI
  • BioCyc: see SPNINV200_RS00770
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    ATGTTTAAAATAAAAGATAATTATATTTACAGGCAATGCGTTAATGATTCTATACTGATA
    GAAAAACTTAATGAAAATAATCTTGAAATATTTTTTGATAGCAAAATATTTCAAGAGATG
    TTGATGGTGGCGAATCCACGATTTTTTAATGAATTAACTAAGGAAAAAATATATCAAAAT
    TCTACGTTTAGAAATTATGCAAAGAGGTCGCTTACAAGAGCAACTCCATTTGGATTGTTT
    AGTTCAGTTGGTGTTGGTTCTTTTTCAAAAGTTTCATACCCTCAACAGATTAGAGAGAAT
    TATAGTAAAAAAGTGTCTGTTAGTGGAGAGTGGATTAGTTCGCTTTGTATGATGTTAGAA
    AATGAAGATTCAGTTTTATTGCAATTACATTTACAGTGGAATCAAAAAGTACTGGAGCTA
    TCAGATAAGTATCAATTGAATAATATCAACTATTGGGGTGTTTCCGAGCAGAGTAGAGAT
    ATACTTATCAAGAAAACTGCCCTTTTAGAATTTATTAAAAAATTGACATATAAATCGGAA
    GTAAGTGTATTAGACTTGGTACAAGAAATTCAAACTAAGTCTCCTAATTTGGAGACACAG
    AAAATTATTGATTATTTACGTAATTTAATTATCAGTGAATTTTTATTTACAAACTTACGA
    AAGGTTGTAATAAATCACAATTGTTTAGATAATTTAATTTATATTTTAAGTTCTATTAAT
    GAGCAAACAAAATTAACTACTGATTTGTTACAACTTAAATCATGCATCGAGAAGTATTCA
    AAATCAGAGTTAGGAGAAGGTATTCTTCAATATGCTGAAATTTGTGAAAAAATGTCTCAT
    ATTTTTAATGAAGAAAAACAGCGCTATCTGAAGGTTGACTTAGTGAATAGTTATGATTCG
    CTATTACCCAAAGATTTAAAAAAGACATTGGAGGACTTCGTTAACTTTATTTCGAGAATT
    AATCTGGGTAAAGATTATCGAAATAAGGAATTAATCTCGTACACAGAAAAATTTGTCGAA
    AAATACGGAGAGTATGTTGAAGTTCCTATTAAGCAACTACTGGATAGTAAGTTAGGGTTG
    GGGATACCAAAACAAAATTTGGAACCTTATAGTATATTATCAAGTGTTGCAGAACAAACT
    TTTTTGTCTTATCTAAGTAAAGAAATCTTTAAAGCAGTGAAAAATAATAAAAAGGAAATT
    GATATATCAAATATTCCGCCTGAATTATTGTATCCAAATTTGGATAGATTTGCTGTGAAT
    CAGTTCGAGTTGTATTGTGAAATGAAGAATTTTGGAGAACAACCTGTTATATCAATTGTG
    CCAAATACTGGGAGTGATATGATAGGAAAGTCTATTGGTAGATTTGCTTCATATTTTCTA
    AATTCTAATATAGAATTAGATTCGAGGGTTGATAATGTAGAATTAATAGAATTTCCAAGT
    GATAATAAAAATTTAAATGTTATGTCTTCTCACCATGGACATTCTAAAAAGTTATTACTA
    TCTTATGAAGATGACTTTGATATTGACTCGTTAGAATTAGATTTCTTAGTAGTGGGTGTT
    GAGAGAGTGAATGAGCATTACAAACTATATTTTAGAGACTTACGAACAGACTTGATTGTT
    AATTTTGTAACAACCTCAATGCTGAATCATAAATCTATCGGAGTTTTTAGCCATTTAGCG
    AGATTTTTGTTAACAGTTTCGTTAGAGTGGCAAGATAATCCATTTTCTCTATTTAGGGTA
    ATTGAGAATCTTGATTTCCTTCCTTATATTCCTAGAATTAAATATAAGAATATTATTTTA
    AGTGAAGAGAAGTGGATTTTATCAGATGTCGATAAAAAAGATATGTCTACTATTAGTCAG
    TGGAAAAAATTTTTTGATGTACCTAGCCTTCTATACTTTCATAAAGATGATGAGCGTTTA
    CTGATTGACCTAAAGAATAGTTTAGATGTTCAATGGATTTTAAAACAAAATGTTGATAAA
    TTACATTTTACGCGTTTTGATAAGATTGATGGTAAAAATTGCGAGTTTATCTTTGGATTT
    GAAAATCCTCGAAATAGTGTATACCCTCATTCAGTAAGTGAAAAAACTGTCAGAAGAATT
    GAAAATGACTTTTATAAAGATTATGTAAAAACGTTTTCGAGCGATTGGATATATTTCAAA
    TTATATGGAATTAACTCCTCAACGATGCCTGAACTAAGAGAAAATCTTCTTATATTCACT
    GATGAGCTTTTAGCTGAGAAATTAGTTAGTGATTTTCATTTTGTAAATTATAATGATGGC
    GGGGATGGTTCTATTAGATTAAGGTTTAAAATTATGAACGAAGATGATTTTGAAAAGCTA
    AGATATCGAATTATTCATTGGATAGATTTCCTATTAAATCATTATTTTTGTAAAGATGTA
    AGTTTTAATTTATATGAGAGGGAGGTTGAGAGATATGGAGGTATTGGCTTTTTAACAGTA
    TGTGAGAGGATATTTTCTATTGATAGTTATCTTGTTTTAAAGTTGTTTTCAAAGAAAGTA
    TTAAAAGTTGATGATTATTTATCTGTTCTACATTCAATTTTTATATATATCCGACTATTG
    GGAATATCTCCAAAACAATTACTTAAATTGATGAAGGATACTTTTACTCAAAATATTTAT
    CGTAAAAGTTTTAAAAAGGTGTTTCCCAATAACGCAAAAGTAATAAAGGAATTCAAACAA
    TATTTTGAAGATCAAAGTAAATTTGATATTTTCAATGAAGTTTTTAAAAGCTTCTCACCT
    ATCGAGAAACATTTTGAATATAAAAATGATATGATTCATAGTTTGCTTCATATGCACATG
    AATAGAATAGGAATATTTTCCTTAAATGAAAAGGAATATCTTTATTTTGTGAGGTATATT
    TTAGAGGTATTAAATAATTATGAGAAATATAATATGAGAAATATAATTAAGAAGTATGAT
    GAAATCATCAATAAAGTAGATAGTCTAGTGTTAGACAATAATATTATTGATTTACTACAG
    CGCTCGTGCTATACGGAAAATAGAAGTTACTTGTCGGAATACCCCAGCATAATCATATAT
    TTATCATATAGATTAGCTAATTGCGATGATAACGAGCATTCTAAGTTGCTCTACAATAGA
    GTAAACTACTATTTACATGAACTGTTAAAGTCGATTAAGTTGAACAGTCGTAATAATATA
    TCAATGTGCTATGGATTTTCTGGCTATGTATATGCCTTGAAATTGTTACCTAAGAGGAGT
    AAAGAATATAGTAAATTGCTAGAGACACTTGAAACAATTTTAGTATCTTTAACTAGAGAT
    AGGCTAAGTGAAATAAAAAAATCCAATAAAGTTAAAGAAGAATATATTGATGTAATCCAA
    GGAGTTTCTAGTGTAGGAAAGTATTTTCTTAGCAAGGATAAATTGACTTCTAATCAGGAA
    CTATTATTAAAAGGAGTTTTAAATTATTTAGCAGGAGTAATAAATAATAAGCCAACTATT
    TATCCGGAATATATGCCAAATGAAAAATTAAAGAGAAAATTCCCCAATGGCTATATCAAC
    CTAGGTGTAGCTCATGGTATATTAGGACCACTATATGTTTTAGCATTAGGGTTTAAAAAA
    TTCAACATGCCAGAGTATTTAATTTCGCTAAAAAAGGGTTTGAGTTACTATGAAAAAACT
    TTTCAAACTAATAAGATTGGCAAGATTATTGGCTGGAATGGTAGAGTAAGTGCTGAGGTA
    GAAAGTGAGAAATTCGAATATAATTTAAGTTGGTGTTATGGTAGTCTTGGAATGGCAAGA
    GTACTATATAATATATCTAAAATAATTGACATCCCAAAATTACAAGAGTTAGCTACTGAT
    GTATTCCACTCATCTATTTATTACCTTAATAGTAGTGAAATTTTAAATAACGCAATTTGT
    CATGGTCGCTCTGGGATAATGCTTTTGTTCAACTTGATGTATTTAGACACAGGGGAATCA
    CAGTTTAAAGCTATTTCTGATAATTTATTTAAGGAAATAGTAAATAAAGCCACTGATTCT
    GAATACATATTTGTGGAACGTGATATATATTTTAGGGGTGTGAATTATGATGAAGTGATA
    GAGTATATTGATTTTTGCTTGTTAAATGGGGTTTCTGGGATAGTTCTTGCACTAATGGCG
    CAGAGGACAGGAAATGCTTCTCCTTTGGCTGAAATGTTTTTTATGCAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4191

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNINV200_01410 [new locus tag: SPNINV200_RS00770 ]
  • symbol: SPNINV200_01410
  • description: Lantibiotic biosynthesis protein
  • length: 1396
  • theoretical pI: 7.34354
  • theoretical MW: 163995
  • GRAVY: -0.247278

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance thiopeptide-type bacteriocin biosynthesis domain (TIGR03891; HMM-score: 201.1)
  • TheSEED  :
    • Lanthionine biosynthesis cyclase LanC
  • PFAM:
    no clan defined Lant_dehydr_N; Lantibiotic dehydratase, N terminus (PF04738; HMM-score: 261.5)
    and 3 more
    6_Hairpin (CL0059) LANC_like; Lanthionine synthetase C-like protein (PF05147; HMM-score: 142.4)
    no clan defined Lant_dehydr_C; Lantibiotic biosynthesis dehydratase C-term (PF14028; HMM-score: 67.1)
    ACT (CL0070) Thr_dehydrat_C; C-terminal regulatory domain of Threonine dehydratase (PF00585; HMM-score: 16.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.17
    • Cytoplasmic Membrane Score: 9.51
    • Cellwall Score: 0.16
    • Extracellular Score: 0.15
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.1795
    • Cytoplasmic Membrane Score: 0.6702
    • Cell wall & surface Score: 0.0019
    • Extracellular Score: 0.1484
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001302
    • TAT(Tat/SPI): 0.000082
    • LIPO(Sec/SPII): 0.000319
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW33775 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFKIKDNYIYRQCVNDSILIEKLNENNLEIFFDSKIFQEMLMVANPRFFNELTKEKIYQNSTFRNYAKRSLTRATPFGLFSSVGVGSFSKVSYPQQIRENYSKKVSVSGEWISSLCMMLENEDSVLLQLHLQWNQKVLELSDKYQLNNINYWGVSEQSRDILIKKTALLEFIKKLTYKSEVSVLDLVQEIQTKSPNLETQKIIDYLRNLIISEFLFTNLRKVVINHNCLDNLIYILSSINEQTKLTTDLLQLKSCIEKYSKSELGEGILQYAEICEKMSHIFNEEKQRYLKVDLVNSYDSLLPKDLKKTLEDFVNFISRINLGKDYRNKELISYTEKFVEKYGEYVEVPIKQLLDSKLGLGIPKQNLEPYSILSSVAEQTFLSYLSKEIFKAVKNNKKEIDISNIPPELLYPNLDRFAVNQFELYCEMKNFGEQPVISIVPNTGSDMIGKSIGRFASYFLNSNIELDSRVDNVELIEFPSDNKNLNVMSSHHGHSKKLLLSYEDDFDIDSLELDFLVVGVERVNEHYKLYFRDLRTDLIVNFVTTSMLNHKSIGVFSHLARFLLTVSLEWQDNPFSLFRVIENLDFLPYIPRIKYKNIILSEEKWILSDVDKKDMSTISQWKKFFDVPSLLYFHKDDERLLIDLKNSLDVQWILKQNVDKLHFTRFDKIDGKNCEFIFGFENPRNSVYPHSVSEKTVRRIENDFYKDYVKTFSSDWIYFKLYGINSSTMPELRENLLIFTDELLAEKLVSDFHFVNYNDGGDGSIRLRFKIMNEDDFEKLRYRIIHWIDFLLNHYFCKDVSFNLYEREVERYGGIGFLTVCERIFSIDSYLVLKLFSKKVLKVDDYLSVLHSIFIYIRLLGISPKQLLKLMKDTFTQNIYRKSFKKVFPNNAKVIKEFKQYFEDQSKFDIFNEVFKSFSPIEKHFEYKNDMIHSLLHMHMNRIGIFSLNEKEYLYFVRYILEVLNNYEKYNMRNIIKKYDEIINKVDSLVLDNNIIDLLQRSCYTENRSYLSEYPSIIIYLSYRLANCDDNEHSKLLYNRVNYYLHELLKSIKLNSRNNISMCYGFSGYVYALKLLPKRSKEYSKLLETLETILVSLTRDRLSEIKKSNKVKEEYIDVIQGVSSVGKYFLSKDKLTSNQELLLKGVLNYLAGVINNKPTIYPEYMPNEKLKRKFPNGYINLGVAHGILGPLYVLALGFKKFNMPEYLISLKKGLSYYEKTFQTNKIGKIIGWNGRVSAEVESEKFEYNLSWCYGSLGMARVLYNISKIIDIPKLQELATDVFHSSIYYLNSSEILNNAICHGRSGIMLLFNLMYLDTGESQFKAISDNLFKEIVNKATDSEYIFVERDIYFRGVNYDEVIEYIDFCLLNGVSGIVLALMAQRTGNASPLAEMFFMQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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