PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 11-FEB-2025

⊟Summary

• organism: Streptococcus pneumoniae INV200
• locus tag: SPNINV200_RS11160 [old locus tag: SPNINV200_00160 ]
• pan locus tag^?: PNEUPAN000379000
• symbol: SPNINV200_RS11160
• pan gene symbol^?: —
• synonym:
• product: IS630 family transposase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPNINV200_RS11160 [old locus tag: SPNINV200_00160 ]
• symbol: SPNINV200_RS11160
• product: IS630 family transposase
• replicon: chromosome
• strand: +
• coordinates: join(20410..20728,20728..21257)
• length: 849
• essential: unknown

⊟Accession numbers

• Location: NC_017593 join(20410..20728,20728..21257) NCBI
• BioCyc: SPNINV200_RS11160 BioCyc
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_2070 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  
  ATGGCATATTCAATAGATTTTCGTAAAAAAGTTCTCTCTTATTGTGAGCGAACAGGTAGT
  ATAACAGAAGCATCACACGTTTTCCAAATCTCACGTAATACTATTTATGGCTGGTTAAAG
  CTAAAAGAGAAGACAGGAGAGCTAAACCACCAAGTAAAAGGAACAAAACCAAGAAAAGTT
  GATAGAGATAGACTTAAAAACTATCTTACTGACAATCCAGACGCTTATTTGACTGAAATA
  GCTGCTGAATTTGATTGTCATCCAACTACTATCCACTATGCTCTCAAAGCTATGGGCTAC
  ACTCGAAAAAAAAGAACCAACACCTACTATGAACAAGACACAGAAAAAGTAGCTTTATTT
  CTTAAGAATTTTAATAGTTTAAAGCACCTAGCACCTGTTTATATTGATGGAACAGGATTT
  GATACTTATTTTTATCGAGAGTATGGTCGCTCATTAAAAGGTCAGTTAAGAAGAGGTAAA
  GTATCTGGAAGAAGATATCAGAGGATTTCTTTGGTTGCAGGGCTAACAAATGGTGAGTTA
  ATCGCTCCAATGACTTACGAAGAGACGATGACGAGCGACTTTTTTGAAGCATGGTTTCAG
  AAGTTTCTCTTACCAACGTTAAATACACCCTCAGTTATTATTATGGATAATGCAAGATTC
  TATAGAATGGCTAAGATAGAACTCTTGTGTGAAGAGTTTGGGCATAAACTTTTACCCCTT
  CCTCCCTACTCACCTGAGTACAATCCTATTGAGAAAACATGGGCTCATATCAAAAAGCAC
  CTCAAAAAGGTATTACCAAGTTGCAATACCTTTTACGAGGCTCTTTTCTCTTGTTCTTGT
  TTCAATTGA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  849
  

⊟Protein

⊟General

• locus tag: SPNINV200_RS11160 [old locus tag: SPNINV200_00160 ]
• symbol: SPNINV200_RS11160
• description: IS630 family transposase
• length: 282
• theoretical pI: 9.55605
• theoretical MW: 32939.7
• GRAVY: -0.502128

⊟Function

• TIGRFAM:
• TheSEED: see SPNINV200_00160
• PFAM:
  HTH (CL0123) HTH_Tnp_IS630; Transposase (PF01710; HMM-score: 98.9)
  RNase_H (CL0219) DDE_3; DDE superfamily endonuclease (PF13358; HMM-score: 88)
  and 13 more
  HTH (CL0123) HTH_28; Helix-turn-helix domain (PF13518; HMM-score: 35.9)
  HTH_23; Homeodomain-like domain (PF13384; HMM-score: 23.8)
  HTH_29; Winged helix-turn helix (PF13551; HMM-score: 22.4)
  HTH_17; Helix-turn-helix domain (PF12728; HMM-score: 21.7)
  HTH_33; Winged helix-turn helix (PF13592; HMM-score: 20.7)
  HTH_30; PucR C-terminal helix-turn-helix domain (PF13556; HMM-score: 18.8)
  HTH_Tnp_ISL3; Helix-turn-helix domain of transposase family ISL3 (PF13542; HMM-score: 16.3)
  RNase_H (CL0219) rve; Integrase core domain (PF00665; HMM-score: 14.9)
  DDE_Tnp_ISAZ013; Rhodopirellula transposase DDE domain (PF07592; HMM-score: 13.5)
  HTH (CL0123) FeoC; FeoC like transcriptional regulator (PF09012; HMM-score: 13.5)
  HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 12.7)
  CENP-B_N; CENP-B N-terminal DNA-binding domain (PF04218; HMM-score: 12.6)
  Retroviral_zf (CL0511) CLIP1_ZNF; CLIP1 zinc knuckle (PF16641; HMM-score: 11.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 1.78
  • Cytoplasmic Membrane Score: 8.16
  • Cellwall Score: 0.06
  • Extracellular Score: 0.01
  • Internal Helices: 0
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.004458
  • TAT(Tat/SPI): 0.000538
  • LIPO(Sec/SPII): 0.001355
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_128973861 NCBI
• UniProt:

⊟Protein sequence

• MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEKTGELNHQVKGTKPRKVDRDRLKNYLTDNPDAYLTEIAAEFDCHPTTIHYALKAMGYTRKKRTNTYYEQDTEKVALFLKNFNSLKHLAPVYIDGTGFDTYFYREYGRSLKGQLRRGKVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEAWFQKFLLPTLNTPSVIIMDNARFYRMAKIELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALFSCSCFN

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V: SPV_2070 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications