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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV200
  • locus tag: SPNINV200_RS12805 [old locus tag: SPNINV200_15910 ]
  • pan locus tag?: PNEUPAN003230000
  • symbol: SPNINV200_RS12805
  • pan gene symbol?: psrP
  • synonym:
  • product: accessory Sec-dependent serine-rich glycoprotein adhesin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNINV200_RS12805 [old locus tag: SPNINV200_15910 ]
  • symbol: SPNINV200_RS12805
  • product: accessory Sec-dependent serine-rich glycoprotein adhesin
  • replicon: chromosome
  • strand: -
  • coordinates: 1621663..1625097
  • length: 3435
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017593 (1621663..1625097) NCBI
  • BioCyc: SPNINV200_RS12805 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    ATATTTTTTAGACGTCAGAAGGGTGAATATAGAGAAACAGACCGAGTAACTCGGTTCAAA
    TTAATCAAATCAGGGAAGCATTGGCTACGGGCCTCGACTTCTCTTTTTGGCTTGTTTAAG
    GTCATGCGTGGTGGTGTTGATACTACTCAGGTCATGACCGAAACGGTAGAAGATAAAGTA
    AGTCATTCAATTACTGGGCTTGATATCCTCAAGGGAATAGCTGCTGTGGGAGCTGTCATA
    AGTGGAACCGTTGCAACTCAAACGAAGGTATTTACAAATGAGTCGGCAGTACTTGAAAAA
    ACTGTAGAGAAAACGGATGCTTTGGCAACAAATGGTACAGTAGTTCTAGGTACGATATCT
    ACAAGTAATTCAGCGAGTTCAACTAGTTTGTCAGCTTCAGAGTCGGCAAGTACATCTGCA
    TCTGAGTCAGCCTCAACCAGCGCTTCGACCTCAGCGAGTACAAGTGCATCAGAATCAGCA
    AGTACATCGGCTTCGACAAGTATCTCTGCATCATCTACTGTGGTAGGTTCACAAACAGCT
    GCCGCTACAGAAGCAACTGCTAAGAAGGTCGAAGAAGATCGTAAGAAACCAGCTAGTGAT
    TATGTAGCATCAGTTACAAATGTCAATCTCCAATCTTATGCTAAGCGACGCAAGCGTTCA
    GTGGATTCCATCGAGCAATTGCTGGCTTCTATAAAAAATGCTGCTGTTTTTTCTGGCAAT
    ACGATTGTAAATGGCGCCCCTGCAATTAATGCAAGTCTAAACATTGCTAAAAGTGAGACA
    AAAGTTTACACGGGTACAGGTAAAGATTCATTTTATAATATTCCAATTTACTATCAATTG
    ACAGTGATAAATGATGGTTCAAAATTGACCTTTACCTATACGGTTACGTATGTGAATCCT
    AAAACAAAGACTCTTGGTAATATATCAAAAAAGATGAGTAATGGATATTCTATCTATAAT
    ACAGGAACTTCAATACAAACAATGTTAACCCTTGGCAGTGGTCTTGGTAAACCTTCAGGT
    GTAAAGAACTCCATTACTGACAAAAATGGTAAACAGGTTCGACCCTATAATACATCTACA
    ATGACGATGTGGCGTAGTGGGTATACTTGGGCAAATGGTGCCCAAATGAATGGTTTCTTT
    GCTAAGAAAGGATATGGATTAACATCATCTTGGACTGTACCAATTACTGGAACGGATACA
    TCCTTTACATTTACCCCTTACGCTGCTAAAACAGATAGAATCGGAACTAACTACTTCAAT
    GGTACAAGAAAGGTAGTTGAATCTAGCACGACCAGTCAGTCACTTTCACAGTCTAAGTCA
    CTATCAGTAAGTGCTAGTCAAAGCGCCTCAGCTTCAGCATCGACAAGCGCTTCAGCTTCA
    GCAAGCACAAGTACGTCAGCAAGTACATTGGCTTCAACAAGTGCAAGTACGTCGGCATCA
    ACAAGCGCGTCGACCTCAGCAAGTACATCAGCATCAACAAGCGCGTCGACCTCAGCAAGT
    ACATCGGCATCAACAAGCGCAAGTACGTCAGCAAGTACATCGGCATCAACAAGCGCAAGT
    ACGTCAGCAAGCACGTCAGCATCAACAAGCGCAAGCACGTCAGCAAGCACGTCAGCATCA
    ACAAGCGCAAGTACATCGGCAAGCACGTCAGCATCGACAAGTGCAAGTACGTCAGCAAGC
    ACGTCAGCATCAACAAGCGCAAGCACGTCAGCATCGACAAGTGCAAGTACGTCAGCAAGT
    ACATCGGCATCAACAAGCGCGTCGACCTCAGCAAGCACGTCAGCAAGCACATCGGCATCA
    ACAAGCGCAAGTACGTCAGCAAGTACATCGGCATCAACAAGCGCAAGTACGTCAGCAAGC
    ACATCAGCATCAACAAGCGCAAGTACGTCAGCAAGCACGTCAGCTTCAACAAGCGCAAGT
    ACATCGGCAAGCACGTCAGCATCGACAAGTGCAAGTACGTCAGCAAGCACGTCAGCTTCA
    ACAAGCGCAAGTACATCGGCAAGCACGTCAGCATCGACAAGTGCAAGTACGTCAGCAAGC
    ACGTCAGCTTCAACAAGCGCAAGTACATCGGCAAGCACGTCAGCATCGACAAGTGCAAGT
    ACGTCAGCAAGTACATCGGCATCAACAAGCGCGTCGACCTCAGCAAGCACGTCAGCAAGC
    ACATCGGCATCAACAAGCGCAAGTACGTCAGCAAGTACATCGACTTCAACAAGCGCAAGC
    ACGTCAGCATCAACAAGTGCAAGTACGTCAGCAAGTACATCGGCATCAACAAGCGCGTCG
    ACCTCAGCAAGCACGTCAGCAAGCACATCGGCATCAACAAGCGCGTCGACCTCAGCAAGC
    ACGTCAGCAAGCACATCGGCATCAACAAGCGCAAGTACGTCAGCAAGTACATCGACTTCA
    ACAAGCGCAAGCACGTCAGCATCAACAAGTGCAAGTACGTCAGCAAGTACATCGGCATCA
    ACAAGCGCGTCGACCTCAGCAAGCACGTCAGCAAGCACATCGGCATCAACAAGCGCAAGT
    ACGTCAGCAAGTACATCGGCATCAACAAGCGCAAGCACGTCAGCATCAACAAGCGCAAGC
    ACGTCAGCAAGCACGTCAGCATCAACAAGCGCAAGTACGTCAGCAAGCACGTCCGCATCA
    ACAAGCGCAAGTACATCGGCAAGCACGTCAGCATCGACAAGTGCAAGTACGTCAGCAAGC
    ACGTCAGCTTCAACAAGCGCAAGCACGTCCGCATCAACAAGCGCGTCGGCCTCAGCAAGT
    ACGTCAGCATCAACAAGCGCGTCGGCCTCAGCAAGTACGTCCGCATCAACAAGCGCGTCG
    GCCTCAGCAAGTACGTCCGCATCAACAAGCGCGTCGACCTCAGCAAGTACATCGGCATCA
    ACAAGTGCAAGTACATCGGCATCAACAAGCGCGTCGGCCTCAGCAAGTACATCGGCATCA
    ACAAGCGCAAGCACGTCAGCATCAACAAGCGCAAGCACGTCAGCATCAACAAGCGCAAGC
    ACGTCAGCAAGCACGTCAGCTTCAACAAGCGCAAGTACATCGGCAAGCACGTCAGCAAGT
    ACATCGGCATCAACAAGCGCGTCGACCTCAGCAAGTACATCAGCATCAACAAGCGCGTCG
    ACCTCAGCAAGTACATCAGCTTCAGCAAGTACCAGTGCGTCGGCTTCAGCGTCGACAAGT
    GCGTCAGCTTCTGAATCGGCATCAACGAGTGCCTCAGCTTCAGCAAGCACAAGCGCGTCA
    GTAAGTACCTCTGAGTCAACAAGTACAAGTGGATCAACTAATTCTCGACCACAAGAGACA
    ATAACCAATTCAAGACAGGAATTACCAAATACAGGAGAGAAACAGTCTGTGAAATCAGGA
    CTTCTTGGATTGATACTTGGTTTAACAGGTTTAGGATTGGTTGCCAAACGTCGTAAAAGA
    GATGATGAAGACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3435

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNINV200_RS12805 [old locus tag: SPNINV200_15910 ]
  • symbol: SPNINV200_RS12805
  • description: accessory Sec-dependent serine-rich glycoprotein adhesin
  • length: 1144
  • theoretical pI: 10.2982
  • theoretical MW: 108777
  • GRAVY: -0.218094

⊟Function[edit | edit source]

  • TIGRFAM:
    serine-rich repeat adhesion glycoprotein (TIGR04224; HMM-score: 71)
    and 3 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 30.2)
    KxYKxGKxW signal peptide (TIGR03715; HMM-score: 30.1)
    Cell structure Cell envelope Surface structures PEP-CTERM protein-sorting domain (TIGR02595; HMM-score: 9)
  • TheSEED: see SPNINV200_15910
  • PFAM:
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 38.4)
    KxYKxGKxW_sig; KxYKxGKxW signal peptide (PF19258; HMM-score: 37.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.028946
    • TAT(Tat/SPI): 0.007405
    • LIPO(Sec/SPII): 0.002248
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_172631721 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIAAVGAVISGTVATQTKVFTNESAVLEKTVEKTDALATNGTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKPASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASIKNAAVFSGNTIVNGAPAINASLNIAKSETKVYTGTGKDSFYNIPIYYQLTVINDGSKLTFTYTVTYVNPKTKTLGNISKKMSNGYSIYNTGTSIQTMLTLGSGLGKPSGVKNSITDKNGKQVRPYNTSTMTMWRSGYTWANGAQMNGFFAKKGYGLTSSWTVPITGTDTSFTFTPYAAKTDRIGTNYFNGTRKVVESSTTSQSLSQSKSLSVSASQSASASASTSASASASTSTSASTLASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSTSTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSTSTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASASASTSASTSASASASTSASTSASASASTSASTSASTSASTSASTSASTSASTSASASASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASASTSASASASTSASASESASTSASASASTSASVSTSESTSTSGSTNSRPQETITNSRQELPNTGEKQSVKSGLLGLILGLTGLGLVAKRRKRDDED

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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