PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 26-AUG-2017

⊟Summary

• organism: Streptococcus pneumoniae OXC141
• locus tag: SPNOXC16230 [new locus tag: SPNOXC_RS08805 ]
• pan locus tag^?: PNEUPAN003372000
• symbol: SPNOXC16230
• pan gene symbol^?: dpnC
• synonym:
• product: Methylase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPNOXC16230 [new locus tag: SPNOXC_RS08805 ]
• symbol: SPNOXC16230
• product: Methylase
• replicon: chromosome
• strand: -
• coordinates: 1646309..1647073
• length: 765
• essential: unknown

⊟Accession numbers

• Location: FQ312027 (1646309..1647073) NCBI
• BioCyc: see SPNOXC_RS08805
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_1631 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  721
  
  ATGGAATTACATTTTAATTTAGAATTAGTAGAAACCTATAAAAGTAATAGCCAAAAGGCA
  CGTATCTTAACGGAGGATTGGGTTTATCGTCAGTCTTATTGCCCTAATTGTGGGAACAAT
  CCCTTAAATCATTTTGAAAATAATCGGCCTGTAGCAGATTTTTACTGTAATCATTGTAGT
  GAGGAGTTTGAACTAAAGAGCAAAAAAGGAAATTTTTCATCAACAATCAATGATGGTGCT
  TATGCAACGATGATGAAGCGTGTGCAGGCAGATAATAATCCTAATTTCTTTTTTTTAACT
  TACACAAAAAATTTTGAGGTAAATAACTTTCTTGTCCTTCCGAAGCAATTTGTTACACCG
  AAATCGATTATTCAAAGAAAACCACTTGCACCAACTGCTAGACGAGCAGGTTGGATTGGT
  TGTGACATTGATTTATCACAAGTACCTTCTAAAGGAAGGATATTTCTTGTGCAAGATGGA
  CAAGTTAGAGATCCAGAAAAAGTTACAAAAGAATTTAAGCAAGGTTTATTTTTAAGGAAG
  AGCTCTCTGTCATCAAGAGGTTGGACAATAGAAATTCTAAATTGTATAGATAAGATAGAG
  GGTTCAGAATTTACCCTTGAAGATATGTATCGTTTTGAAAGTGACCTAAAAAATATCTTT
  GTTAAGAACAATCATATCAAAGAAAAGATTAGGCAACAGCTTCAAATATTAAGAGACAAA
  GAAATAATAGAATTTAAAGGTAGAGGAAAGTATCGGAAATTATGA
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  765
  

⊟Protein

⊟General

• locus tag: SPNOXC16230 [new locus tag: SPNOXC_RS08805 ]
• symbol: SPNOXC16230
• description: Methylase
• length: 254
• theoretical pI: 9.48444
• theoretical MW: 29785.9
• GRAVY: -0.640551

⊟Function

• TIGRFAM:
  Genetic information processing Mobile and extrachromosomal element functions Prophage functions restriction alleviation protein, Lar family (TIGR03655; HMM-score: 13.7)
  Genetic information processing DNA metabolism Restriction/modification restriction alleviation protein, Lar family (TIGR03655; HMM-score: 13.7)
  Signal transduction Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 12.1)
• TheSEED  :
  • Type II restriction enzyme DpnI (dpnC)
• PFAM:
  PDDEXK (CL0236) DpnI; Dam-replacing family (PF06044; HMM-score: 283.5)
  and 11 more
  HTH (CL0123) DpnI_C; Dam-replacing HTH domain (PF17726; HMM-score: 120.2)
  Zn_Beta_Ribbon (CL0167) zinc-ribbons_6; zinc-ribbons (PF07191; HMM-score: 16.2)
  Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 16.2)
  Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 13.8)
  Prim_Zn_Ribbon; Zinc-binding domain of primase-helicase (PF08273; HMM-score: 13.7)
  zf-TFIIB; Transcription factor zinc-finger (PF13453; HMM-score: 12.6)
  no clan defined DUF3797; Domain of unknown function (DUF3797) (PF12677; HMM-score: 12.2)
  Zn_Beta_Ribbon (CL0167) Nudix_N_2; Nudix N-terminal (PF14803; HMM-score: 11)
  zf-ribbon_3; zinc-ribbon domain (PF13248; HMM-score: 10)
  TF_Zn_Ribbon; TFIIB zinc-binding (PF08271; HMM-score: 9.4)
  HVO_2753_ZBP; Small zinc finger protein HVO_2753-like, Zn-binding pocket (PF07754; HMM-score: 8.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.8079
  • Cytoplasmic Membrane Score: 0.0121
  • Cell wall & surface Score: 0.001
  • Extracellular Score: 0.1791
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.119877
  • TAT(Tat/SPI): 0.001773
  • LIPO(Sec/SPII): 0.013836
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: CBW33275 NCBI
• UniProt:

⊟Protein sequence

• MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCDIDLSQVPSKGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V: SPV_1631 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications