Jump to navigation
Jump to search
PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 25-OCT-2019
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae NU83127
- locus tag: SPNU_0054 [new locus tag: EL277_RS00300 ]
- pan locus tag?: PNEUPAN000678000
- symbol: purE
- pan gene symbol?: purE
- synonym:
- product: N5-carboxyaminoimidazole ribonucleotide mutase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPNU_0054 [new locus tag: EL277_RS00300 ]
- symbol: purE
- product: N5-carboxyaminoimidazole ribonucleotide mutase
- replicon: chromosome
- strand: +
- coordinates: 55882..56370
- length: 489
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AP018936 (55882..56370) NCBI
- BioCyc: see EL277_RS00300
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0059 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481ATGAAACCAGTAATTTCCATCATCATGGGCTCAAAATCCGACTGGGCAACCATGCAAAAA
ACAGCAGAAGTCCTAGACCGCTTCGGTGTAGCCTACGAAAAGAAAGTTGTTTCCGCACAC
CGTACACCAGACCTCATGTTCAAACATGCAGAAGAAGCCCGTAGTCGTGGCATCAAGATC
ATCATCGCAGGTGCTGGTGGCGCAGCGCATTTGCCAGGCATGGTAGCTGCCAAAACAACC
CTTCCAGTCATTGGTGTGCCAGTCAAGTCTCGTGCTCTTAGTGGAGTGGATTCACTCTAT
TCTATCGTTCAGATGCCGGGTGGGGTGCCTGTTGCGACCATGGCTATCGGTGAAGCTGGA
GCGACTAACGCAGCTCTCTTTGCCCTCCGTCTCCTCTCTGTAGAAGATAAGTCCATTGCG
GATGCACTTGCCAACTTTGCTGAAGAACAAGGAAAAATCGCAGAGGAGTCGTCAAATGAG
CTCATCTAA60
120
180
240
300
360
420
480
489
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPNU_0054 [new locus tag: EL277_RS00300 ]
- symbol: PurE
- description: N5-carboxyaminoimidazole ribonucleotide mutase
- length: 162
- theoretical pI: 7.78178
- theoretical MW: 16945.6
- GRAVY: 0.22716
⊟Function[edit | edit source]
- TIGRFAM: Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis phosphoribosylaminoimidazole carboxylase, catalytic subunit (TIGR01162; EC 4.1.1.21; HMM-score: 215.6)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: DHQS (CL0224) AIRC; AIR carboxylase (PF00731; HMM-score: 212.4)and 1 moreFe-ADH_2; Iron-containing alcohol dehydrogenase (PF13685; HMM-score: 16.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.32
- Cytoplasmic Membrane Score: 9.55
- Cellwall Score: 0.12
- Extracellular Score: 0.01
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.8236
- Cytoplasmic Membrane Score: 0.0012
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.1751
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.037848
- TAT(Tat/SPI): 0.00192
- LIPO(Sec/SPII): 0.002461
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: BBG33945 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPDLMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSIVQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNELI
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0059 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]