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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NU83127
  • locus tag: SPNU_0622 [new locus tag: EL277_RS03330 ]
  • pan locus tag?: PNEUPAN001600000
  • symbol: msrAB_1
  • pan gene symbol?: msrAB_1
  • synonym:
  • product: Peptide methionine sulfoxide reductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNU_0622 [new locus tag: EL277_RS03330 ]
  • symbol: msrAB_1
  • product: Peptide methionine sulfoxide reductase
  • replicon: chromosome
  • strand: +
  • coordinates: 635164..635730
  • length: 567
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGAAAAAATGGCAAACATGTGTTCTTGGAGCAGGTTCGCTCCTTTGTTTGACGGCTTGT
    TCAGGCAAGTCCGTGACTAGTGAACACCAAACGAAAGATGAAATGAAGACGGAGCAGACA
    GCTAGTAAAACAAGCGCAGCTAAAGGGAAAGAGGTGGCTGATTTTGAATTGATGGGAGTA
    GATGGCAAGACCTACCGTTTATCTGATTACAAGGGCAAGAAAGTCTATCTCAAATTCTGG
    GCTTCTTGGTGTTCCATCTGTCTGGCTAGTCTTCCAGATACGGATGAGATTGCTAAAGAA
    GCTGGTGATGACTATGTGGTCTTGACAGTAGTGTCACCAGGACATAAGGGAGAGCAATCT
    GAAGCGGACTTTAAGAATTGGTATAAGGGATTGGATTATAAAAATCTCCCAGTCCTAGTT
    GACCCATCAGGCAAACTTTTGGAAACTTATGGTGTCCGTTCTTACCCAACCCAAGCCTTT
    ATAGACAAAGAAGGCAAGCTGGTCAAAACACATCCAGGATTCATGGAAAAAGATGCAATT
    TTGCAAACTTTGAAGGAATTAGCCTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    567

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNU_0622 [new locus tag: EL277_RS03330 ]
  • symbol: MsrAB_1
  • description: Peptide methionine sulfoxide reductase
  • length: 188
  • theoretical pI: 7.336
  • theoretical MW: 20775.7
  • GRAVY: -0.413298

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein folding and stabilization periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily (TIGR00385; HMM-score: 40.9)
    Metabolism Energy metabolism Electron transport thioredoxin (TIGR01068; HMM-score: 40.4)
    and 2 more
    Genetic information processing Protein fate Protein folding and stabilization protein disulfide-isomerase domain (TIGR01126; HMM-score: 27.8)
    protein disulfide isomerase (TIGR01130; HMM-score: 18.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Thioredoxin (CL0172) Redoxin; Redoxin (PF08534; HMM-score: 71.8)
    AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 68.6)
    and 4 more
    Thioredoxin; Thioredoxin (PF00085; HMM-score: 33.4)
    Thioredoxin_8; Thioredoxin-like (PF13905; HMM-score: 32.8)
    Thioredoxin_2; Thioredoxin-like domain (PF13098; HMM-score: 32.1)
    SCO1-SenC; SCO1/SenC (PF02630; HMM-score: 15.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.11
    • Cytoplasmic Membrane Score: 0.93
    • Cellwall Score: 8.19
    • Extracellular Score: 0.77
    • Internal Helices: 0
  • SignalP: Signal peptide LIPO(Sec/SPII) length 19 aa
    • SP(Sec/SPI): 0.001503
    • TAT(Tat/SPI): 0.000083
    • LIPO(Sec/SPII): 0.998191
    • Cleavage Site: CS pos: 19-20. LTA-CS. Pr: 0.9957
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG34513 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKTSAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAGDDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAFIDKEGKLVKTHPGFMEKDAILQTLKELA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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