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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NU83127
  • locus tag: SPNU_1680 [new locus tag: EL277_RS08845 ]
  • pan locus tag?: PNEUPAN003221000
  • symbol: SPNU_1680
  • pan gene symbol?: —
  • synonym:
  • product: Putative acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNU_1680 [new locus tag: EL277_RS08845 ]
  • symbol: SPNU_1680
  • product: Putative acetyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1672999..1673814
  • length: 816
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: AP018936 (1672999..1673814) NCBI
  • BioCyc: see EL277_RS08845
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    TTGGATTATCTCCTTGAAAACTTGCCAAATATCTGTTTTCATATTGCAGCGCCTGTCCAG
    TTTTCCGAGAAAATCCGTAGCTTAGAAACGAACTATAATGTCCGTCTCCGAACGATTACA
    AATGAAGAACAGCTAAACTTTCTAGTCGATACCTGTGACTTTTTACTAGATATCAATCAC
    TTTCAAGAAGTAGATGCTATTGTCTCCAAGTTTGTACAGGCTGGAAAATCTGTCTTTGCA
    TTTGACAATACAGTCCATGGAAATCAGGGGCAGGAAGTTTTTCTATCAAGTACACCAGAT
    AAATTGGTTTCTAGAGTGAGAGACTATCTGAATGAAGTCAGAGTAGGCACCAATCATCAA
    GAAAAAATCATCCAAGATGGGACTTGGAATGTCTTTAAAATCGATGATAAGGCTCACTTC
    ATTGTAGGAGCAAATGTCATCTGCAGAAATTTTGAAAATTGTCATGTCTCTTCTGGTAAG
    TTAATACTGCATGATGGTGTTTTTATCAACAACTCTTGTAGTTTTAACTGTATGGAAAGA
    ATTGAAATCGGAGCTGGTACCATGATGGGAGAGGGTGTTCGTTTTTATGATCACGACCAT
    ATTTATACTGCTGAAAAGATTGAAAAGTGGCAGTGGACTACAGCGCCGATTAGAGTTGGC
    AGAGACTGCTGGATAGGAAGTAATGTCACGATTTTAAAAGGAGTGATGATTGGGGATAAT
    ACCATTATTGGAGCAGGTTGTCTCATACGCAATGATATTCCATCAAACAGTGTAGTTTAT
    AATAATGGAAATCTTTTTGTAAAGAGAAGAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    816

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNU_1680 [new locus tag: EL277_RS08845 ]
  • symbol: SPNU_1680
  • description: Putative acetyltransferase
  • length: 271
  • theoretical pI: 6.03042
  • theoretical MW: 30767.7
  • GRAVY: -0.165683

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein modification and repair accessory Sec system glycosyltransferase GtfB (TIGR02919; EC 2.4.1.-; HMM-score: 62.7)
    and 15 more
    sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family (TIGR03570; HMM-score: 43.3)
    colanic acid biosynthesis acetyltransferase WcaF (TIGR04008; EC 2.3.1.-; HMM-score: 43.3)
    phosphonate metabolim protein, transferase hexapeptide repeat family (TIGR03308; HMM-score: 33.9)
    2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (TIGR03532; EC 2.3.1.89; HMM-score: 31.8)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 26.6)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 26.6)
    Metabolism Central intermediary metabolism Amino sugars UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 26.6)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (TIGR01853; EC 2.3.1.191; HMM-score: 25.3)
    Metabolism Amino acid biosynthesis Serine family serine O-acetyltransferase (TIGR01172; EC 2.3.1.30; HMM-score: 25.1)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase (TIGR01852; EC 2.3.1.129; HMM-score: 23)
    colanic acid biosynthesis acetyltransferase WcaB (TIGR04016; EC 2.3.1.-; HMM-score: 19.7)
    non-ribosomal peptide synthetase terminal domain of unknown function (TIGR02353; HMM-score: 17.2)
    Metabolism Energy metabolism Other phenylacetic acid degradation protein PaaY (TIGR02287; HMM-score: 16.6)
    2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (TIGR03536; EC 2.3.1.117; HMM-score: 14)
    UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR03992; EC 2.3.1.157,2.7.7.23; HMM-score: 12.3)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    HEXAPEP (CL0536) Hexapep; Bacterial transferase hexapeptide (six repeats) (PF00132; HMM-score: 38.9)
    Hexapep_2; Hexapeptide repeat of succinyl-transferase (PF14602; HMM-score: 32.9)
    and 2 more
    sPC4_like (CL0609) DUF3276; Protein of unknown function (DUF3276) (PF11680; HMM-score: 12.7)
    AB_hydrolase (CL0028) Hydrolase_4; Serine aminopeptidase, S33 (PF12146; HMM-score: 11)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9618
    • Cytoplasmic Membrane Score: 0.0046
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0335
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004764
    • TAT(Tat/SPI): 0.00017
    • LIPO(Sec/SPII): 0.000462
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG35562 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDYLLENLPNICFHIAAPVQFSEKIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAFDNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAHFIVGANVICRNFENCHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYDHDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVMIGDNTIIGAGCLIRNDIPSNSVVYNNGNLFVKRRD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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