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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae P1031
- locus tag: SPP_1389 [new locus tag: SPP_RS06845 ]
- pan locus tag?: PNEUPAN002645000
- symbol: SPP_1389
- pan gene symbol?: pheA
- synonym:
- product: prephenate dehydratase (PDT)
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPP_1389 [new locus tag: SPP_RS06845 ]
- symbol: SPP_1389
- product: prephenate dehydratase (PDT)
- replicon: chromosome
- strand: -
- coordinates: 1296664..1297512
- length: 849
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000920 (1296664..1297512) NCBI
- BioCyc: see SPP_RS06845
- MicrobesOnline: 7481882 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1203 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841ATGAAAATTGCTTATCTAGGTCCCAAGGGATCATTTTCACACCACGTTGTGCAGATAGCT
TTTCCTCATGAGGAATTGCAGGCTTTTGCTAACATTACAGATGTCATCAAGGCTTATGAG
CAAGGATTAGTGGACTATTCTGTGGTGCCAGTTGAAAATTCTATTGAGGGTAGTGTTCAT
GAAACCTTGGACTATCTTTTTCATCAGGCTCACATCCAAGCAGTAGCAGAAATCGTTCAG
CCTATTCATCAGCAGTTGATGGTGGTTCCAGGCCATACTAAGATTGAAAAGATTTTTTCA
CATCCACAGGCCTTGGCTCAAGGAAAGAAATTCATCGATGAACAATATCCAGAGGCTCAA
ATCGAGGTAACAGCTAGTACAGCTTATGCGGCCCGTTTTATTTCCGAACATCCAGACCAG
CCCTTTGCAGCAGTTGCACCTAGAAGTTCTGCTGAAGAATATGGATTGGAACTGATTGCC
GAGGATATTCAGGAAATGGAAGCCAATTTCACACGTTTCTGGGTTCTAGGAGCTGAAAAG
CCTAGTATTCCCTTGCAAGCACAAACTGAAAAGATGAGTTTGGCCTTGACATTACCTGAC
AACCTTCCAGGTGCACTTTATAAGGCCCTGTCGACCTTTGCTTGGCGAGGAATTGACTTG
ACAAAAATTGAAAGTCGTCCACTCAAGACAGCACTGGGTGAATACTTTTTCATTATCGAT
GTGGATTATACCGATAAGGACTTGGTCCACTTTGCCCAAAAAGAATTAGAAGCGATTGGA
ATCCAGTATAAAATTCTGGGTGCCTATCCTATTTATCCAATATCAGACCATGGAAAGGAG
AGAAGATGA60
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849
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPP_1389 [new locus tag: SPP_RS06845 ]
- symbol: SPP_1389
- description: prephenate dehydratase (PDT)
- length: 282
- theoretical pI: 5.0505
- theoretical MW: 31662.8
- GRAVY: -0.142908
⊟Function[edit | edit source]
- reaction: EC 4.2.1.51? ExPASyPrephenate dehydratase Prephenate = phenylpyruvate + H2O + CO2
- TIGRFAM: phenylalanine-4-hydroxylase (TIGR01268; EC 1.14.16.1; HMM-score: 24.7)
- TheSEED :
- Prephenate dehydratase (EC 4.2.1.51)
Amino Acids and Derivatives Aromatic amino acids and derivatives Chorismate Synthesis Prephenate dehydratase (EC 4.2.1.51)and 2 more - PFAM: PBP (CL0177) PDT; Prephenate dehydratase (PF00800; HMM-score: 193.2)and 2 moreACT (CL0070) ACT; ACT domain (PF01842; HMM-score: 18.4)ATP-grasp (CL0179) ATP-grasp_4; ATP-grasp domain (PF13535; HMM-score: 12.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9993
- Cytoplasmic Membrane Score: 0.0002
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0004
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.022197
- TAT(Tat/SPI): 0.000676
- LIPO(Sec/SPII): 0.000809
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: ACO21386 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLVDYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHPQALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIAEDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGIDLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISDHGKERR
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SPP_1388 < SPP_1389 < aroK < aroA
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1203 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]