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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae P1031
  • locus tag: SPP_1518 [new locus tag: SPP_RS07450 ]
  • pan locus tag?: PNEUPAN002781000
  • symbol: SPP_1518
  • pan gene symbol?: pgm
  • synonym:
  • product: phosphomannomutase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPP_1518 [new locus tag: SPP_RS07450 ]
  • symbol: SPP_1518
  • product: phosphomannomutase
  • replicon: chromosome
  • strand: +
  • coordinates: 1404048..1405766
  • length: 1719
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGTCTTACCAAGAAAATTACCAGAAATGGGTTGATTTTGTGGAGCTTCCTGACTACCTT
    CGTCAAGATTTGGAAAATATGGACGAAAAAACTAAGGAAGATGCCTTCTATACAAATCTT
    GAATTTGGTACTGCAGGTATGCGTGGCTTGGTTGGTGCTGGTACAAACCGTATCAACATC
    TACGTTGTTCGCCAAGCTACTGAAGGATTGGCTCGTTTGATTGAGTCAAAAGGTGGAAAC
    GAGAAAGAACGCGGTGTAGCAATTGCCTACGATAGCCGTCACTTCTCACCTGAGTTTGCC
    TTTGAATCTGCGGCAGTTCTTGCTAAACACGGCATCAAATCTTACGTATTTGAAAGCCTT
    CGTCCAACTCCAGAACTATCATTTGCAGTTCGTCATCTCAACTGTTTCGCAGGTATCATG
    GTCACAGCCAGCCACAACCCTGCTCCATTTAACGGTTACAAGGTTTACGGTGAAGACGGT
    GGACAAATGCCTCCACACGATGCGGACGCTTTGACTACTTATATCCGTGCAATCGAAAAC
    CCATTTGCAGTTGAAGTTGCTGATGTGGAAACTGAAAAAGCTTCTGGCTTGATTGAAGTT
    ATCGGCGAAGCTGTTGACGTAGAATACCTTAAAGAGGTTAAGGACGTAAACATCAACCCA
    GCCTTGATTGAAGAATTTGGTAAAGACATGAAGATTGTCTACACACCACTTCATGGTACT
    GGTGAAATGTTGGCTCGTCGTGCTCTTGCCCAAGCAGGATTTGACTCTGTTCAAGTTGTT
    GAAGCGCAAGCAACTGCTGACCCAGACTTCTCAACTGTAACATCTCCAAACCCAGAAAGC
    CAAGCAGCCTTTGCCCTTGCTGAAGAACTTGGTCGTCAAGTTGGTGCAGATGTTCTTGTC
    GCAACTGACCCAGACGCTGACCGTGTTGGTGTTGAAGTTCTTCAAAAAGATGGTAGCTAC
    CTCAACCTTTCAGGTAACCAAATCGGTGCTATCATGGCTAAATACATCTTGGAAGCTCAC
    AAAAACGCTGGAACTCTTCCTGAAAATGCCGCTCTCTGCAAATCTATCGTTTCAACTGAC
    TTGGTAACGAAGATTGCTGAAAGCTACGGCGCAACTATGTTCAACGTCTTGACAGGTTTC
    AAATTTATCGCTGAAAAAATCCAAGAATTCGAAGAAAAACACAACCACACTTACATGATG
    GGATTTGAAGAAAGCTTCGGTTACTTGATTAAACCATTTGTACGTGATAAAGATGCCATC
    CAAGCCGTTCTTGTCGTTGCTGAACTTGCTGCCTACTACCGTTCTCGTGGTTTGACACTT
    GCTGACGGTATCGAAGAAATCTATAAAGAATATGGCTACTACGCAGAAAAAACAATCTCT
    GTTACTCTTTCAGGTGTCGATGGTGCTGAACAAATCAAAGCGATTATGGCTAAATTCCGC
    AACAATGCTCCAACAGAATGGAACGCAACAGCTATCACTGTCGTAGAAGACTTCAAGGCA
    CAAACTGCTACTGTTGCTGACGGTACTGTTACAAACTTGACAACTCCTCCAAGTGATGTG
    TTGAAATACACACTTGCTGACGGTTCATGGATTGCCGTTCGCCCTTCAGGTACAGAACCA
    AAAATCAAGTTCTACATTGCAGTTGTAGGGGAAACCAACGAAGAATCACAAGCTAAGATT
    GCTAACATCGAAGCAGAAATCAATGCATTTGTAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1719

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPP_1518 [new locus tag: SPP_RS07450 ]
  • symbol: SPP_1518
  • description: phosphomannomutase
  • length: 572
  • theoretical pI: 4.45808
  • theoretical MW: 62642.1
  • GRAVY: -0.171329

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Central intermediary metabolism Amino sugars phosphoglucosamine mutase (TIGR03990; EC 5.4.2.10; HMM-score: 158.4)
    and 4 more
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan phosphoglucosamine mutase (TIGR01455; EC 5.4.2.10; HMM-score: 88.5)
    Metabolism Central intermediary metabolism Amino sugars phosphoglucosamine mutase (TIGR01455; EC 5.4.2.10; HMM-score: 88.5)
    Metabolism Energy metabolism Sugars phosphoglucomutase, alpha-D-glucose phosphate-specific (TIGR01132; EC 5.4.2.2; HMM-score: 68.9)
    Metabolism Central intermediary metabolism One-carbon metabolism probable H4MPT-linked C1 transfer pathway protein (TIGR03123; HMM-score: 16.4)
  • TheSEED  :
    • Phosphoglucomutase (EC 5.4.2.2)
  • PFAM:
    no clan defined PGM_PMM_I; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I (PF02878; HMM-score: 141.5)
    and 5 more
    PGM_PMM_II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II (PF02879; HMM-score: 81.7)
    PGM_PMM_III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III (PF02880; HMM-score: 79.7)
    PGM_PMM_IV; Phosphoglucomutase/phosphomannomutase, C-terminal domain (PF00408; HMM-score: 42.8)
    TetR_C (CL0174) TetR_C_12; Bacterial transcriptional repressor C-terminal (PF16914; HMM-score: 14)
    no clan defined LytR_C; LytR cell envelope-related transcriptional attenuator (PF13399; HMM-score: 13.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9939
    • Cytoplasmic Membrane Score: 0.0007
    • Cell wall & surface Score: 0.0006
    • Extracellular Score: 0.0048
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009143
    • TAT(Tat/SPI): 0.035923
    • LIPO(Sec/SPII): 0.000316
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO21184 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGTAGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFESAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDGGQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNINPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSPNPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAKYILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEEKHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKEYGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADGTVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAEINAFVK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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