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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 22-NOV-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae P1031
- locus tag: SPP_RS03680 [old locus tag: SPP_0756 ]
- pan locus tag?: PNEUPAN001687000
- symbol: upp
- pan gene symbol?: upp
- synonym:
- product: uracil phosphoribosyltransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPP_RS03680 [old locus tag: SPP_0756 ]
- symbol: upp
- product: uracil phosphoribosyltransferase
- replicon: chromosome
- strand: +
- coordinates: 688445..689074
- length: 630
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012467 (688445..689074) NCBI
- BioCyc: SPP_RS03680 BioCyc
- MicrobesOnline: see SPP_0756
- PneumoBrowse for strain D39V: SPV_0649 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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601ATGGGAAAAATTGAAGTTATTAATCACCCACTGATTCAACACAAATTGTCAATCTTGCGT
CGTATAGATACTTCTACAAAAGCTTTTCGTGAGCTAGTAGATGAGATTGCAATGTTGATG
GGGTATGAAGTACTTCGTGATCTTCCACTAGAAGATGTGGAAATCGAAACACCAATTACA
AAAACAGTTCAAAAACAATTGGCAGGTAAGAAATTGGCCATCGTCCCAATCTTGCGTGCA
GGTATCGGGATGGTTGATGGTCTCTTGAGCTTGGTTCCAGCTGCTAAAGTTGGCCACATC
GGTATGTACCGTGATGAAGAAACACTTCAACCAGTTGAATACTTGGTGAAATTGCCTGAG
GACATTGACCAACGTCAAATTTTTGTAGTAGACCCAATGTTGGCAACAGGTGGCTCAGCA
ATCTTGGCTGTTGATTCTCTTAAAAAACGTGGCGCATCAAATATCAAATTTGTCTGCCTT
GTATCTGCTCCAGAGGGTGTAAAAGCCCTTCAAGAAGCTCATCCAGATGTAGAAATCTTT
ACAGCAGCCTTGGATGAACGTTTGAACGAACACGGTTATATCGTTCCAGGTCTTGGAGAT
GCTGGAGACCGCTTGTTCGGTACAAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPP_RS03680 [old locus tag: SPP_0756 ]
- symbol: Upp
- description: uracil phosphoribosyltransferase
- length: 209
- theoretical pI: 5.35464
- theoretical MW: 22883.6
- GRAVY: 0.100478
⊟Function[edit | edit source]
- reaction: EC 2.4.2.9? ExPASyUracil phosphoribosyltransferase UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate
- TIGRFAM: Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uracil phosphoribosyltransferase (TIGR01091; EC 2.4.2.9; HMM-score: 301.8)and 6 morePurines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis ribose-phosphate diphosphokinase (TIGR01251; EC 2.7.6.1; HMM-score: 26.8)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides hypoxanthine phosphoribosyltransferase (TIGR01203; EC 2.4.2.8; HMM-score: 26.4)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine phosphoribosyltransferase (TIGR01090; EC 2.4.2.7; HMM-score: 15.2)Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR01367; EC 2.4.2.10; HMM-score: 14.7)Cellular processes DNA transformation comF family protein (TIGR00201; HMM-score: 12.7)Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR00336; EC 2.4.2.10; HMM-score: 12.7)
- TheSEED: see SPP_0756
- PFAM: PRTase-like (CL0533) UPRTase; Uracil phosphoribosyltransferase (PF14681; HMM-score: 260.4)and 1 morePribosyltran; Phosphoribosyl transferase domain (PF00156; HMM-score: 45.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9616
- Cytoplasmic Membrane Score: 0.0073
- Cell wall & surface Score: 0.0003
- Extracellular Score: 0.0308
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001802
- TAT(Tat/SPI): 0.000174
- LIPO(Sec/SPII): 0.000228
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_001846793 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEVLRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCLVSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0649 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]