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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 22-NOV-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae P1031
- locus tag: SPP_RS06200 [old locus tag: SPP_1251 ]
- pan locus tag?: PNEUPAN002450000
- symbol: truB
- pan gene symbol?: truB
- synonym:
- product: tRNA pseudouridine(55) synthase TruB
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPP_RS06200 [old locus tag: SPP_1251 ]
- symbol: truB
- product: tRNA pseudouridine(55) synthase TruB
- replicon: chromosome
- strand: -
- coordinates: 1169483..1170361
- length: 879
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012467 (1169483..1170361) NCBI
- BioCyc: SPP_RS06200 BioCyc
- MicrobesOnline: see SPP_1251
- PneumoBrowse for strain D39V: SPV_1070 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841ATGAACGGTATTATCAACTTAAAAAAAGAAGCAGGAATGACCTCGCATGATGCGGTTTTT
AAACTGCGTAAGATTTTGGGAACCAAGAAAATTGGTCATGGTGGAACCTTGGATCCGGAT
GTGGTGGGTGTTTTGCCGATTGCGGTTGGCAAGGCGACACGCATGGCCGAGTTTATGCAG
GACGAGGGTAAGATCTATGAGGGGGAAATTACTCTGGGTTATTCCACGACGACTGAGGAT
ACTAGTGGGGAAGTGATCGCAGAAACCCCTGTTTTGTCTCCCTTGGATGAAAAGCTTGTT
GATGAAGCGATTGCTAGCTTGACTGGGCCTATTACCCAGATTCCCCCTATGTATTCGGCA
GTTAAGGTTAATGGTCGCAAGCTCTATGAGTATGCGCGTGCTGGTCAGGAAGTGGAGCGT
CCAGAACGTCAGGTGACCATTTATCAATTTGAGCGAACAAGTCCGATTTCTTATGATGGC
CAACTTGCCCGATTCACTTTTCGTGTAAAATGCAGTAAAGGGACTTACATCCGTACTTTG
TCAGTTGATTTGGGTGAAAAGCTTGGTTATGCGGCTCATATGTCCCATTTGACTCGTACT
AGTGCTGCTGGCTTACAATTAGAAGACGCTCTTGCCTTGGAGGAAATTGCTGAAAAAGTA
GAGGCTGGGCAATTAGATTTTCTCCATCCTTTAGAGATTGGGACAGGTGACCTTGTCAAA
GTTTTCCTAACTCCAGAAGAGGCTACAGAAGTTCGCTTTGGTCGTTTTATTGAGCTAGAC
CAAACGGACAAAGAACTGGCTGCCTTTGAAGATGATAAATTGTTAGCCATTCTAGAAAAA
CGGGGCAATCTCTATAAGCCAAGGAAGGTTTTTAGCTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPP_RS06200 [old locus tag: SPP_1251 ]
- symbol: TruB
- description: tRNA pseudouridine(55) synthase TruB
- length: 292
- theoretical pI: 5.03265
- theoretical MW: 32257.7
- GRAVY: -0.241781
⊟Function[edit | edit source]
- reaction: EC 5.4.99.25? ExPASytRNA pseudouridine55 synthase tRNA uridine55 = tRNA pseudouridine55
- TIGRFAM: Protein synthesis tRNA and rRNA base modification tRNA pseudouridine(55) synthase (TIGR00431; EC 5.4.99.25; HMM-score: 251.4)and 1 moreProtein synthesis tRNA and rRNA base modification putative rRNA pseudouridine synthase (TIGR00425; EC 5.4.99.-; HMM-score: 118.4)
- TheSEED: see SPP_1251
- PFAM: PseudoU_synth (CL0649) TruB_N; TruB family pseudouridylate synthase (N terminal domain) (PF01509; HMM-score: 187.6)and 2 moreTruB_C_2; tRNA pseudouridylate synthase B C-terminal domain (PF16198; HMM-score: 39.6)PUA (CL0178) TruB_C; tRNA Pseudouridine synthase II, C terminal (PF09142; HMM-score: 24.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9991
- Cytoplasmic Membrane Score: 0.0002
- Cell wall & surface Score: 0
- Extracellular Score: 0.0007
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006669
- TAT(Tat/SPI): 0.000631
- LIPO(Sec/SPII): 0.000942
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_001013234 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVLPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDTSGEVIAETPVLSPLDEKLVDEAIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDGQLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAEKVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKRGNLYKPRKVFS
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1070 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]