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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae P1031
  • locus tag: SPP_RS06335 [old locus tag: SPP_1280 ]
  • pan locus tag?: PNEUPAN002520000
  • symbol: zwf
  • pan gene symbol?: zwf
  • synonym:
  • product: glucose-6-phosphate dehydrogenase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPP_RS06335 [old locus tag: SPP_1280 ]
  • symbol: zwf
  • product: glucose-6-phosphate dehydrogenase
  • replicon: chromosome
  • strand: +
  • coordinates: 1197510..1198997
  • length: 1488
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_012467 (1197510..1198997) NCBI
  • BioCyc: SPP_RS06335 BioCyc
  • MicrobesOnline: see SPP_1280
  • PneumoBrowse for strain D39V: SPV_1100 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGTCATCTAAGGTTATTGTTACAATTTTCGGTGCGAGTGGAGACCTGGCTAAACGCAAG
    CTCTACCCTTCCCTTTTTAGACTATATCAATCCGGCAATCTTTCCAAGCACTTTGCCGTT
    ATTGGAACTGCCCGTAGACCTTGGAGTAAGGAATATTTTGAATCTGTAGTTGTCGAGTCC
    ATCCTTGATTTGGCAGATAGTACCGAGCAAGCCCAAGAATTTGCTAGCCACTTCTACTAT
    CAAAGCCATGATGTCAATGATTCGGAACATTATATTGCTTTGCGTCAATTACAAGCTGAG
    CTTAATGAAAAATACCAAGCTGAACACAATAAGCTCTTCTTCTTGTCTATGGCACCTCAG
    TTCTTTGGAACCATTGCCAAACACCTCAAATCTGAAAACATTGTCGATGGCAAAGGTTTT
    GAGCGCTTGATCGTTGAAAAACCATTTGGTACAGATTACGCAACTGCAAGCAAGTTGAAT
    GTCGAACTCCTAGCAACATTTGACGAAGAACAAATTTTCCGTATCGACCATTATCTTGGT
    AAGGAAATGATCCAAAGCATCTTTGCAGTTCGCTTTGCAAACTTGATTTTTGAAAACGTT
    TGGAACAAGGATTTTATCGACAATGTTCAAATTACCTTTGCGGAGCGCTTGGGTGTAGAA
    GAACGTGGTGGCTACTATGACCAATCCGGTGCCCTCCGTGACATGGTCCAAAACCACACT
    CTACAACTTCTTTCGCTCCTCGCCATGGACAAACCAGCAAGCTTCACAAAAGACGAGATT
    CGTGCTGAAAAGATTAAGGTCTTTAAAAACCTCTATCATCCAACTGATGAAGAACTCAAA
    GAACACTTTATCCGTGGGCAATACCGCTCTGGTAAGATTGATGGCATGAAATACATCTCT
    TATCGTAGCGAGCCAAATGTGAATCCAGAATCAACAACTGAAACCTTTACATCTGGTGCC
    TTCTTTGTAGACAGCGATCGATTCCGTGGTGTTCCTTTCTTTTTCCGTACAGGTAAACGA
    CTGACTGAAAAAGGAACTCATGTCAACATCGTCTTTAAACAAATGGATTCTATCTTTGGA
    GAACCACTTGCTCCAAATATTTTGACCATCTATATTCAACCAACAGAAGGCTTCTCTCTT
    AGCCTAAATGGGAAGCAAGTAGGAGAAGAATTTAACTTGGCTCCTAACTCACTTGATTAC
    CGTACAGATGCGACTGCAACTGGTGCTTCTCCAGAACCATACGAAAAATTGATTTATGAT
    GTCCTAAATAACAACTCAACTAACTTTAGCCACTGGGATGAAGTTTGTGCGTCATGGAAG
    TTGATTGACCGTATTGAAAAGCTCTGGGCTGAAAATGGTGCCCCACTTCATGACTATAAA
    GCTGGAAGCATGGGACCTCAAGCCAGCTTTGACCTACTTGAAAAATTCGGTGCCAAATGG
    ACTTGGCAACCAGATATCGCCTATCGTCAAGATGGTCGTTTCGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1488

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPP_RS06335 [old locus tag: SPP_1280 ]
  • symbol: Zwf
  • description: glucose-6-phosphate dehydrogenase
  • length: 495
  • theoretical pI: 5.50937
  • theoretical MW: 56777.5
  • GRAVY: -0.433131

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Pentose phosphate pathway glucose-6-phosphate dehydrogenase (TIGR00871; EC 1.1.1.49; HMM-score: 554.5)
  • TheSEED: see SPP_1280
  • PFAM:
    GADPH_aa-bio_dh (CL0139) G6PD_C; Glucose-6-phosphate dehydrogenase, C-terminal domain (PF02781; HMM-score: 353.8)
    and 3 more
    NADP_Rossmann (CL0063) G6PD_N; Glucose-6-phosphate dehydrogenase, NAD binding domain (PF00479; HMM-score: 197.6)
    S11_L18p (CL0267) Host_attach; Protein required for attachment to host cells (PF10116; HMM-score: 13.3)
    GBD (CL0202) Bac_rhamnosid_N; Alpha-L-rhamnosidase N-terminal domain (PF08531; HMM-score: 11.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004808
    • TAT(Tat/SPI): 0.00042
    • LIPO(Sec/SPII): 0.002051
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000096168 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTARRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELNEKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLNVELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLGVEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTDEELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFFFRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFNLAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWAENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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