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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 22-NOV-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae P1031
  • locus tag: SPP_RS06970 [old locus tag: SPP_1414 ]
  • pan locus tag?: PNEUPAN002671000
  • symbol: phoU
  • pan gene symbol?: phoU2
  • synonym:
  • product: phosphate signaling complex protein PhoU

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPP_RS06970 [old locus tag: SPP_1414 ]
  • symbol: phoU
  • product: phosphate signaling complex protein PhoU
  • replicon: chromosome
  • strand: -
  • coordinates: 1323298..1323951
  • length: 654
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012467 (1323298..1323951) NCBI
  • BioCyc: SPP_RS06970 BioCyc
  • MicrobesOnline: see SPP_1414
  • PneumoBrowse for strain D39V: SPV_1227 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTTACGATCTCAATTTGAAGAAGATTTAGAGAAATTACATAACCAGTTCTACGCTATG
    GGACAAGAAGTGCTCTCACAAATCAATCGTACGGTACGTGCTTTTGTCACGCATGACCGT
    GACCTGGCAAAAGAGGTCATAGAAGATGATGCAGAAGTAAATGAATACGAAGTGAAACTG
    GAAAAGAAATCATTTGAAATGATCGCACTCCAACAACCAGTCTCTCAAGATTTGCGTACA
    GTCTTGACTGTCCTTAAGGCTGTATCAGATGTGGAGCGTATGGGGGATCACGCTGTAGCC
    ATTGCCCAGGCAACCATCCGTATGAAGGGGGAAGAACGCATCCCAGCTGTAGAGGAAGAA
    ATTAAAAAAATGGGACGTGAAGTTAAAAGCGTTGTTGAAGCAGCACTTGATCTTTATCTT
    AATGGTTCTGTTGACGACGCATACCGGGTGGCCTCCATGGATGAGCAAATTAACCACTAT
    TTTGAAACTATCCGTGACCTTGCGACTGAAGAGATTAAGAAAAATCCAGAAGCCATTGTT
    ACGGGTCGTGATTATTTCCAAGTTATTTCCTACTTGGAGCGTATCGGTGATTATGCTAAA
    AATATCTGTGAATGGGTTGTCTACTTTGAAACAGGTAAGATTGTCGAACTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    654

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPP_RS06970 [old locus tag: SPP_1414 ]
  • symbol: PhoU
  • description: phosphate signaling complex protein PhoU
  • length: 217
  • theoretical pI: 4.45154
  • theoretical MW: 25028.2
  • GRAVY: -0.356221

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Anions phosphate transport system regulatory protein PhoU (TIGR02135; HMM-score: 255)
    Signal transduction Regulatory functions Other phosphate transport system regulatory protein PhoU (TIGR02135; HMM-score: 255)
    and 1 more
    heme oxygenase, HugZ family (TIGR04109; EC 1.14.99.3; HMM-score: 17.2)
  • TheSEED: see SPP_1414
  • PFAM:
    PhoU (CL0297) PhoU; PhoU domain (PF01895; HMM-score: 139.2)
    and 7 more
    LDH_C (CL0341) Glyco_hydro_4C; Family 4 glycosyl hydrolase C-terminal domain (PF11975; HMM-score: 19.3)
    NTF2 (CL0051) DUF4440; Domain of unknown function (DUF4440) (PF14534; HMM-score: 17.9)
    TPR (CL0020) APC_rep; Adenomatous polyposis coli (APC) repeat (PF18797; HMM-score: 16.8)
    no clan defined DUF4265; Domain of unknown function (DUF4265) (PF14085; HMM-score: 14.7)
    EsxAB (CL0352) DUF5344; Family of unknown function (DUF5344) (PF17279; HMM-score: 13)
    no clan defined Spiralin; Spiralin domain (PF05215; HMM-score: 11)
    DUF16; Protein of unknown function DUF16 (PF01519; HMM-score: 10.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.989
    • Cytoplasmic Membrane Score: 0.0086
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0023
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002813
    • TAT(Tat/SPI): 0.000658
    • LIPO(Sec/SPII): 0.000367
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000946463 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAKEVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIAQATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHYFETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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