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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae P1031
  • locus tag: SPP_RS08860 [old locus tag: SPP_1796 ]
  • pan locus tag?: PNEUPAN003278000
  • symbol: SPP_RS08860
  • pan gene symbol?: dasA
  • synonym:
  • product: sugar ABC transporter substrate-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPP_RS08860 [old locus tag: SPP_1796 ]
  • symbol: SPP_RS08860
  • product: sugar ABC transporter substrate-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1669031..1670341
  • length: 1311
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012467 (1669031..1670341) NCBI
  • BioCyc: SPP_RS08860 BioCyc
  • MicrobesOnline: see SPP_1796
  • PneumoBrowse for strain D39V: SPV_1585 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGCGTAAAGGTACAATGTTATCTGTTGTTGCGGGGCTATCGTTAGCTATACTTGCAGGT
    TGTAGTGGAGGAACTAACTCAAAACAAGCGAGTTCTTCAAATGATATTAAAGTCTGGGTA
    CAATTCTCTGACGAAACAAATGAAGGAAAAGCTTGGCAAAAAGTTGTTGATAACTTTAAT
    CAATCAGGAAAAAGTAAGTACAAGGTTGTAACTGAGTATATTCCTCGTAGTGGTAGTGGT
    GGAGGATATGAAGACAAGGTTAATGCTGCTATTACGACTAATAGTCTTCCAGATGTTATT
    ACCCTTGATGGACCAAATACGGCAGCTTATGCAAAATCTAAAGTAATTACTCCGCTAGAT
    GATTATCTAAAAGATAATAATATGGATGATGTTTTGGACAGTATTAAACAACAGGGAACT
    TATAATGGGAAATTCTATGCATTTGGATTTTCTGAATCGAATGTTGGTGTTTATTACAAT
    AAAAAAATGTTCAAAGAGGCCGGAATTGCGGAATCAGAGCTTCCAACGCTAGAAAAGCCA
    TGGACATGGGACGAATTTAATACGATTGCTAAAAAATTGAAAGATCATTATAACAAACCA
    GCAATTGATTTTCGTATTAATTCAAACGATGAAATGTTGCCATATGCTTATATGCCGTTG
    ATTTGGTCAAATAATGGTTCTGTCGTAAACGAAGATGGAACAAAGGCAGAAGGATACTTC
    AACTCCAAAGAGAGTGTAGAAGCAGTTCAATTCATTCAAAATCTTGTAAAAGAAGGCTAT
    ACAACTGTTAGTCCAGTCGAAAAAGGTTTTGAAACAGGAGAGTATCCAATGCTTTTGAGT
    GGTTCTTGGACGATTGCTGACATGAATACAAACTACAAAGATATTGATTTTGGTATCCTT
    CCTTACCCAGTATCTAGTAAGACGAAAAAATTAGTATCCCCTTCAGGTAGTTGGCAATTA
    GCTGTGACGACAAAATCTGATAAAAAAGAGGCCGCATCTGAATTTGTTAAATTTGCTACA
    AATACAGAATCAAGTGAAATTATTAGCTTGGGGAATTCGGTCCTTCCAATTCGTAAATCT
    ACAATTGAAAATATCAAAGATAAAGTATCCGAACCAATGCGTTTCTTGATGGAACAAAAT
    TCAAAAACAGCTCATGCTCGCCCAGTTGTTGTAGCATATCCTCAGGTTTCTCGAGCTTTT
    CAACAAGCAATGCAAGATATTAGCTATTATGAAGAAAATCCAAATGTGCAAAAAGTCTTG
    GATACTCGTACAAAAGAAATGCAAACTGCTATTGATCAGTCACTCAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1311

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPP_RS08860 [old locus tag: SPP_1796 ]
  • symbol: SPP_RS08860
  • description: sugar ABC transporter substrate-binding protein
  • length: 436
  • theoretical pI: 5.23542
  • theoretical MW: 48445.1
  • GRAVY: -0.515138

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids carbohydrate ABC transporter substrate-binding protein, CPR_0540 family (TIGR03850; HMM-score: 72.6)
    and 1 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein (TIGR03851; HMM-score: 39.8)
  • TheSEED: see SPP_1796
  • PFAM:
    PBP (CL0177) SBP_bac_8; Bacterial extracellular solute-binding protein (PF13416; HMM-score: 133.1)
    SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 126.9)
    and 3 more
    SBP_bac_6; Bacterial extracellular solute-binding protein (PF13343; HMM-score: 22.3)
    E-set (CL0159) NAR2; High-affinity nitrate transporter accessory, Ig-like domain (PF16974; HMM-score: 13.8)
    Histone (CL0012) DUF1931; Domain of unknown function (DUF1931) (PF09123; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • SignalP: Signal peptide LIPO(Sec/SPII) length 20 aa
    • SP(Sec/SPI): 0.000779
    • TAT(Tat/SPI): 0.00008
    • LIPO(Sec/SPII): 0.998956
    • Cleavage Site: CS pos: 20-21. LAG-CS. Pr: 0.9994
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001225468 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSDETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITLDGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYNKKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYMPLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYPMLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASEFVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVAYPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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