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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 22-NOV-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae P1031
- locus tag: SPP_RS11310 [old locus tag: SPP_2294 ]
- pan locus tag?: PNEUPAN003948000
- symbol: rlmH
- pan gene symbol?: rlmH
- synonym:
- product: 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPP_RS11310 [old locus tag: SPP_2294 ]
- symbol: rlmH
- product: 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
- replicon: chromosome
- strand: -
- coordinates: 2109207..2109686
- length: 480
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012467 (2109207..2109686) NCBI
- BioCyc: SPP_RS11310 BioCyc
- MicrobesOnline: see SPP_2294
- PneumoBrowse for strain D39V: SPV_2067 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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421ATGAAAATTAAAGTTGTAACAGTTGGGAAACTGAAAGAAAAGTATTTAAAAGATGGTATC
GCAGAGTATTCAAAACGAATTTCTAGATTTGCTAAGTTTGAAATGATTGAGTTATCAGAT
GAAAAAACACCAGATAAGGCCAGTGAATCAGAAAATCAAAAGATTTTAGAAATAGAAGGT
CAGAGAATTTTATCAAAAATTGCTGACCGTGATTTCGTTATTGTGTTAGCCATTGAAGGG
AAAACTTTCTTCTCAGAAGAATTTAGTAAGCAGTTAGAAGAAACTTCTATAAAAGGATTT
TCTACTCTTACTTTTATTATTGGGGGAAGTTTAGGATTGTCATCATCTGTAAAAAATAGA
GCCAATCTTTCTGTCAGTTTTGGTCGCCTAACCTTACCCCATCAGTTAATGAGACTAGTT
CTTGTTGAACAAATCTATCGCGCTTTTACGATTCAGCAGGGATTCCCCTACCATAAATAG60
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480
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPP_RS11310 [old locus tag: SPP_2294 ]
- symbol: RlmH
- description: 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
- length: 159
- theoretical pI: 9.98813
- theoretical MW: 18098.9
- GRAVY: -0.19434
⊟Function[edit | edit source]
- reaction: EC 2.1.1.177? ExPASy23S rRNA (pseudouridine1915-N3)-methyltransferase S-adenosyl-L-methionine + pseudouridine1915 in 23S rRNA = S-adenosyl-L-homocysteine + N3-methylpseudouridine1915 in 23S rRNA
- TIGRFAM: Protein synthesis tRNA and rRNA base modification rRNA large subunit m3Psi methyltransferase RlmH (TIGR00246; EC 2.1.1.177; HMM-score: 176.2)
- TheSEED: see SPP_2294
- PFAM: SPOUT (CL0098) SPOUT_MTase; Predicted SPOUT methyltransferase (PF02590; HMM-score: 189.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.98
- Cytoplasmic Membrane Score: 0.0006
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0193
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.003673
- TAT(Tat/SPI): 0.000193
- LIPO(Sec/SPII): 0.00059
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTPDKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFSTLTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_2067 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]