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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae P1031
  • locus tag: SPP_RS12060
  • pan locus tag?: PNEUPAN001443000
  • symbol: SPP_RS12060
  • pan gene symbol?: tnp (pseudogene)
  • synonym:
  • product: IS5 family transposase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPP_RS12060
  • symbol: SPP_RS12060
  • product: IS5 family transposase
  • replicon: chromosome
  • strand: -
  • coordinates: join(1158040..1158474,1158476..1158844)
  • length: 804
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012467 join(1158040..1158474,1158476..1158844) NCBI
  • BioCyc: SPP_RS12060 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAATTATGAAGCAAGTAAACAACTAACTGATGCACGATTTAAGCGTCTTGTTGGTGTT
    CAACGCACGACTTTTGAAGAGATATTAGCTGTATTAAAAACAGCTTATCAACTTAAACAC
    GCAAAAGGTGGACGAAAACCTAAATTAAGCCTAGAAGACTTTCTTATGGCCACTCTTCAA
    TATGTGCGAGAATATCGAACTTATGAAGAAATTGCGGCTGATTTTGGTATCCACGAAAGC
    AACTTAATCCGTCGGAGCCGATGGGTTGAAGTAACTCTTGTTCAAAGTGGTGTTACGATT
    TCAAGAACTCCTCTCAGTTCTGAGGACACGGTAATGATTGATGCGACGGAAGTACAAATC
    AATCGCCCTAAAAAACAATTAGCGAATTATTCTGGTAAAAAGAAATTTCACGCTATGAAG
    TCTCAAGCGATTGTCACAAGTCAAGGGAGAATTGTTTCTTTGGATATCGCTGTGAACTAT
    TGTCATGATATGAAGTTGTTCAAAATGAGTCGCAGAAATATCGGACAAGCTGGTAAAATC
    TTGGCTGACAGTGGTTATCAAGGGCTCATGAAGATATATCCTCAAGCACAAATTCCACGT
    AAATCCAGCAAACTCAAGCCGCTAATAGCTGAAGATAAAGCCTATAACCATGCGCTATCT
    AAGGATAGAAGCAAGGTTGAGAACATCTTTGCCAAAGTAAAAACGTTTAAAATGTTTTCA
    ACAACCTATCGAAATCATCGTAAACGCTTCGGATTACGAATGAATTTGAGTGCTGGTATT
    ATCAATCATGAACTAGGATTCTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    804

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPP_RS12060
  • symbol: SPP_RS12060
  • description: IS5 family transposase
  • length: 267
  • theoretical pI: 10.6979
  • theoretical MW: 30584.3
  • GRAVY: -0.460674

⊟Function[edit | edit source]

  • TIGRFAM:
    hopanoid biosynthesis associated membrane protein HpnM (TIGR03481; HMM-score: 13.8)
  • TheSEED:
  • PFAM:
    RNase_H (CL0219) DDE_Tnp_4; DDE superfamily endonuclease (PF13359; HMM-score: 72.3)
    DDE_Tnp_1; Transposase DDE domain (PF01609; HMM-score: 58.1)
    and 3 more
    HTH (CL0123) HTH_Tnp_4; Helix-turn-helix of DDE superfamily endonuclease (PF13613; HMM-score: 47.3)
    RNase_H (CL0219) DDE_Tnp_1_3; Transposase DDE domain (PF13612; HMM-score: 20.3)
    DDE_Tnp_1_6; Transposase DDE domain (PF13751; HMM-score: 14.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002194
    • TAT(Tat/SPI): 0.000489
    • LIPO(Sec/SPII): 0.00068
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_114865960 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGGRKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSRWVEVTLVQSGVTISRTPLSSEDTVMIDATEVQINRPKKQLANYSGKKKFHAMKSQAIVTSQGRIVSLDIAVNYCHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQIPRKSSKLKPLIAEDKAYNHALSKDRSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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