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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
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670-6B
serotype 6B
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serotype 6A
70585
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A66
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AP200
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serotype 23F
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G54
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HU-OH
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Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-NOV-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: SPR_RS00460 [old locus tag: spr0083 ]
  • pan locus tag?: PNEUPAN000724000
  • symbol: SPR_RS00460
  • pan gene symbol?: ABC-SBP_1
  • synonym:
  • product: ABC transporter substrate-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPR_RS00460 [old locus tag: spr0083 ]
  • symbol: SPR_RS00460
  • product: ABC transporter substrate-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 89931..91406
  • length: 1476
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGAAAAACTGGAAAAAATATGCTTTTGCATCTGCTAGTGTAGTCGCTCTGGCTGCAGGT
    CTTGCTGCTTGTGGAAATTTGACAGGTAACAGCAAAAAAGCTGCTGATTCAGGTGACAAA
    CCTGTTATCAAAATGTACCAAATCGGTGACAAACCAGACAACTTGGATGAATTGTTAGCA
    AATGCCAACAAAATCATCGAAGAAAAAGTTGGTGCCAAATTGGATATCCAATACCTTGGC
    TGGGGTGACTATGGTAAGAAAATGTCAGTTATCACATCATCTGGTGAAAACTATGATATT
    GCCTTTGCAGATAACTATATTGTAAATGCTCAAAAAGGTGCTTACGCTGACTTGACAGAA
    TTGTACAAAAAAGAAGGTAAAGACCTTTACAAAGCACTTGACCCAGCTTACATCAAGGGT
    AATACTGTAAATGGTAAGATTTACGCTGTTCCAGTTGCAGCCAACGTTGCATCATCTCAA
    AACTTTGCCTTCAACGGAACTCTCCTTGCTAAATATGGTATCGATATTTCAGGTGTTACT
    TCTTACGAAACTCTTGAGCCAGTCTTGAAACAAATCAAAGAAAAAGCTCCAGACGTAGTA
    CCATTTGCTATTGGTAAAGTTTTCATCCCATCTGATAACTTTGACTACCCAGTAGCAAAC
    GGTCTTCCATTCGTTATCGACCTTGAAGGCGATACTACTAAAGTTGTAAACCGTTACGAA
    GTGCCTCGTTTCAAAGAACACTTGAAGACTCTTCACAAATTCTATGAAGCTGGCTACATT
    CCAAAAGACGTCGCAACAAGCGATACTTCCTTTGACCTTCAACAAGATACTTGGTTCGTT
    CGTGAAGAAACAGTAGGACCAGCTGACTACGGTAACAGCTTGCTTTCACGTGTTGCCAAC
    AAAGATATCCAAATCAAACCAATTACTAACTTCATCAAGAAAAACCAAACAACACAAGTT
    GCTAACTTTGTCATCTCAAACAACTCTAAGAACAAAGAAAAATCAATGGAAATCTTGAAC
    CTCTTGAATACGAATCCAGAACTCTTGAACGGTCTTGTTTACGGTCCAGAAGGCAAGAAC
    TGGGAAAAAATTGAAGGTAAAGAAAACCGTGTTCGCGTTCTTGATGGCTACAAAGGAAAC
    ACTCACATGGGTGGATGGAACACTGGTAACAACTGGATCCTTTACATCAACGAAAACGTT
    ACAGACCAACAAATCGAAAATTCTAAGAAAGAATTGGCAGAAGCTAAAGAATCTCCAGCG
    CTTGGATTTATCTTCAATACTGACAATGTGAAATCTGAAATCTCAGCTATTGCTAACACA
    ATGCAACAATTTGATACAGCTATCAACACTGGTACTGTAGACCCAGATAAAGCGATTCCA
    GAATTGATGGAAAAATTGAAATCTGAAGGTGCCTACGAAAAAGTATTGAACGAAATGCAA
    AAACAATACGATGAATTCTTGAAAAACAAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1476

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPR_RS00460 [old locus tag: spr0083 ]
  • symbol: SPR_RS00460
  • description: ABC transporter substrate-binding protein
  • length: 491
  • theoretical pI: 5.30604
  • theoretical MW: 54485.2
  • GRAVY: -0.470468

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see spr0083
  • PFAM:
    no clan defined DUF3502; Domain of unknown function (DUF3502) (PF12010; HMM-score: 118)
    and 2 more
    Mak16; Mak16 protein C-terminal region (PF04874; HMM-score: 12)
    LppaM (CL0421) LPAM_2; Prokaryotic lipoprotein-attachment site (PF13627; HMM-score: 9.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.63
    • Cell wall & surface Score: 0.0053
    • Extracellular Score: 0.3647
  • SignalP: Signal peptide LIPO(Sec/SPII) length 23 aa
    • SP(Sec/SPI): 0.00546
    • TAT(Tat/SPI): 0.000164
    • LIPO(Sec/SPII): 0.994125
    • Cleavage Site: CS pos: 23-24. LAA-CG. Pr: 0.9945
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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