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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 25-NOV-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae R6
- locus tag: SPR_RS00845 [old locus tag: spr0156 ]
- pan locus tag?: PNEUPAN000874000
- symbol: nrdI
- pan gene symbol?: nrdI
- synonym:
- product: class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
⊟Accession numbers[edit | edit source]
- Location: NC_003098 (164486..164956) NCBI
- BioCyc: see spr0156
- MicrobesOnline: see spr0156
- PneumoBrowse for strain D39V: SPV_0160 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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361
421ATGAAGACAATTTCTTTAGTTTATATTAGTTTGAGTGGCAACACTGAAAGTTTTGTGACG
CGCTTGAAAGACTATCTCTTGTCCCAGTACAAAAGGATTGAGGTTCAAAAGATTCATATC
AAGGATTTGGTCAAGGAAGGCAAAAATTTCTATGAAATGGACCATCCCTATGTCGCTTTT
TTGCCGACCTATCTCGAAGGTGGGAATGGCGTGGATAACGGAGATGTTGAGATTTTGACG
ACACCGGTGGGAGATTTTATTGCCTATGGTAACAATGCTAGTAAGTGTTTTGGTGTGGTT
GGGTCAGGAAATCGTAACTTTAATAACCAATACTGCCTAACAGCCAAGCAATACAGTCAA
CGCTTTGGCTTCCCTGTATTGGCTGACTTTGAAATGCGAGGCATGCTGGAAGATATCAAA
CATGTCGCAGCTATTATCGCAGATTTGTATGAGTTGGAAAAGGAGAATTAA60
120
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471
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPR_RS00845 [old locus tag: spr0156 ]
- symbol: NrdI
- description: class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI
- length: 156
- theoretical pI: 5.24028
- theoretical MW: 17668
- GRAVY: -0.23141
⊟Function[edit | edit source]
- TIGRFAM: Purines, pyrimidines, nucleosides, and nucleotides 2'-Deoxyribonucleotide metabolism nrdI protein (TIGR00333; HMM-score: 64.1)and 2 moreEnergy metabolism Electron transport flavodoxin (TIGR01753; HMM-score: 24.2)putative ribonucleotide reductase-associated flavodoxin (TIGR01754; HMM-score: 21.1)
- TheSEED: see spr0156
- PFAM: Flavoprotein (CL0042) Flavodoxin_NdrI; NrdI Flavodoxin like (PF07972; HMM-score: 137.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9775
- Cytoplasmic Membrane Score: 0.0022
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0202
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.016188
- TAT(Tat/SPI): 0.000224
- LIPO(Sec/SPII): 0.007889
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKTISLVYISLSGNTESFVTRLKDYLLSQYKRIEVQKIHIKDLVKEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGSGNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0160 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Jane A Thanassi, Sandra L Hartman-Neumann, Thomas J Dougherty, Brian A Dougherty, Michael J Pucci
Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae.
Nucleic Acids Res: 2002, 30(14);3152-62
[PubMed:12136097] [WorldCat.org] [DOI] (I p)