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serotype 4
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Hungary19A-6
serotype 19A
EF3030
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670-6B
serotype 6B
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serotype 6A
70585
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serotype 23F
BVJ1JL
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CGSP14
serotype 14
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serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: SPR_RS03920 [old locus tag: spr0780 ]
  • pan locus tag?: PNEUPAN001860000
  • symbol: SPR_RS03920
  • pan gene symbol?: fruA
  • synonym:
  • product: fructose-specific PTS transporter subunit EIIC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPR_RS03920 [old locus tag: spr0780 ]
  • symbol: SPR_RS03920
  • product: fructose-specific PTS transporter subunit EIIC
  • replicon: chromosome
  • strand: +
  • coordinates: 776031..777983
  • length: 1953
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGAAAATTCAAGACCTATTGAGAAAAGATGTCATGTTGCTAGATTTGCAGGCAACTGAA
    AAAACAGCTGTCATCGACGAGATGATTAAAAATTTGACAGAGCACGGTTATGTAACAGAT
    TTTGAAACATTTAAAGAAGGAATTTTGGCGCGTGAAGCTTTGACTTCTACTGGTTTGGGT
    GATGGAATCGCAATGCCTCACAGCAAAAACGCTGCTGTCAAAGAAGCGACAGTTCTATTT
    GCTAAGTCAAATAAGGGTGTTGACTACGAGAGCTTGGATGGACAAGCAACTGACCTCTTC
    TTCATGATTGCAGCTCCAGAAGGTGCCAATGATACTCACTTGGCAGCCTTGGCAGAATTG
    TCTCAATACTTGATGAAAGACGGTTTTGCAGACAAACTTCGTCAAGCAACATCTGCAGAC
    CAAGTTATCGAACTTTTTGACCAAGCTTCAGAAAAAACTGAGGAACTTGTTCAAGCACCT
    GCTAATGACTCTGGTGACTTTATCGTAGCTGTTACAGCTTGTACAACAGGTATTGCCCAC
    ACTTACATGGCCCAAGAAGCCCTTCAAAAAGTAGCTGCTGAAATGGGGGTTGGTATCAAG
    GTCGAAACCAACGGTGCTAGCGGTGTTGGAAATCAACTAACTGCAGAAGATATCCGTAAG
    GCTAAAGCTATTATCATTGCAGCAGACAAGGCCGTTGAAATGGATCGATTTGATGGAAAA
    CCATTGATCAATCGTCCAGTTGCTGACGGTATCCGTAAGACAGAAGAGCTAATTAACTTG
    GCTCTTTCAGGAGATACTGAAGTCTACCGTGCCGCTAATGGTGCCAAAGCTGCAACAGCC
    TCTAACGAAAAACAAAGCCTTGGTGGTGCCTTGTACAAACACTTGATGAGTGGTGTATCT
    CAAATGTTACCATTCGTTATCGGTGGTGGTATCATGATTGCCCTTGCCTTCTTGATTGAC
    GGTGCTTTGGGTGTTCCAAATGAAAACCTTGGCAATCTTGGTTCTTACCATGAGTTAGCT
    TCTATGTTCATGAAAATTGGTGGAGCTGCCTTTGGTTTGATGCTTCCAGTCTTTGCGGGT
    TATGTTGCCTACTCTATTGCTGAAAAACCGGGTTTGGTAGCAGGTTTCGTGGCTGGTGCT
    ATTGCCAAAGAAGGTTTTGCCTTTGGTAAAATTCCTTATGCCGCAGGTGGTGAAGCAACT
    TCAACTCTTGCAGGTGTCTCATCTGGTTTCCTAGGTGCCCTTGTTGGTGGATTTATCGCA
    GGTGCCTTGGTTCTTGCCATCAAGAAATACGTTAAAGTTCCTCGTTCACTCGAAGGTGCT
    AAATCAATCCTTCTATTGCCACTTCTTGGAACAATCTTGACAGGATTTGTTATGCTAGCT
    GTGAATATCCCAATGGCTGCAATCAACACTGCTATGAATGACTTCCTAGGCGGTCTTGGA
    GGAGGTTCAGCTGTCCTTCTTGGTATCGTCCTTGGTGGAATGATGGCTGTTGACATGGGT
    GGACCAGTTAATAAAGCAGCTTATGTCTTTGGTACAGGTACGCTTGCAGCAACTGTTTCT
    TCAGGTGGTTCTGTAGCCATGGCAGCAGTTATGGCTGGAGGAATGGTGCCACCACTTGCA
    ATCTTTGTCGCAACTCTTCTTTTCAAAGATAAATTTACTAAGGAAGAACGTAACTCTGGT
    TTGACAAACATCATCATGGGCTTGTCATTTATCACTGAGGGAGCGATTCCATTTGGTGCC
    GCTGACCCAGCTCGTGCGATTCCAAGCTTCATCCTTGGTTCAGCAGTAGCAGGTGGACTC
    GTTGGTCTTACTGGTATCAAACTCATGGCGCCACACGGAGGAATCTTCGTTATCGCCCTT
    ACTTCAAATGCTCTCCTTTACCTCGTTTCTGTCTTGGTAGGAGCAATCGTAAGTGGTGTG
    GTTTATGGTTACCTACGCAAACCACAAGCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1953

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPR_RS03920 [old locus tag: spr0780 ]
  • symbol: SPR_RS03920
  • description: fructose-specific PTS transporter subunit EIIC
  • length: 650
  • theoretical pI: 5.12732
  • theoretical MW: 66934.5
  • GRAVY: 0.463385

⊟Function[edit | edit source]

  • TIGRFAM:
    PTS system, Fru family, IIC component (TIGR01427; HMM-score: 387.4)
    and 5 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 150.8)
    Signal transduction Signal transduction PTS PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 150.8)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, Fru family, IIB component (TIGR00829; EC 2.7.1.69; HMM-score: 100.8)
    Signal transduction Signal transduction PTS PTS system, Fru family, IIB component (TIGR00829; EC 2.7.1.69; HMM-score: 100.8)
    Signal transduction Signal transduction PTS PTS IIA-like nitrogen-regulatory protein PtsN (TIGR01419; HMM-score: 88.4)
  • TheSEED: see spr0780
  • PFAM:
    PTase-anion_tr (CL0340) PTS_EIIA_2; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (PF00359; HMM-score: 118)
    and 5 more
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 78.8)
    Phosphatase (CL0031) PTS_IIB; PTS system, Lactose/Cellobiose specific IIB subunit (PF02302; HMM-score: 65)
    PDDEXK (CL0236) RestrictionMunI; Type II restriction enzyme MunI (PF11407; HMM-score: 11.9)
    HTH (CL0123) Sigma54_CBD; Sigma-54 factor, core binding domain (PF04963; HMM-score: 11.6)
    no clan defined YuiB; Putative membrane protein (PF14068; HMM-score: 9.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 11
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.0077
    • TAT(Tat/SPI): 0.000981
    • LIPO(Sec/SPII): 0.000476
  • predicted transmembrane helices (TMHMM): 9

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETFKEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFMIAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAPANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDIRKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAKAATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLGSYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIPYAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLGTILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAYVFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIMGLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNALLYLVSVLVGAIVSGVVYGYLRKPQA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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