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serotype 1

NCBI: 25-NOV-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: SPR_RS04915 [old locus tag: spr0981 ]
  • pan locus tag?: PNEUPAN002213000
  • symbol: cpoA
  • pan gene symbol?: lafB
  • synonym:
  • product: alpha-galactosylglucosyldiacylglycerol synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPR_RS04915 [old locus tag: spr0981 ]
  • symbol: cpoA
  • product: alpha-galactosylglucosyldiacylglycerol synthase
  • replicon: chromosome
  • strand: +
  • coordinates: 966767..967891
  • length: 1125
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    GTGAGGAAATTTCCCCTCTTTTCCTCTAGTCTCTCCTTTCTTTTGCTGATTTTATTCAAA
    GAAAATGATATAATAGTAGTTATGGAGAAAAAGAAATTACGCATCAATATGTTGAGTTCA
    AGTGAGAAAGTAGCAGGACAGGGAGTTTCAGGTGCTTACCGTGAATTAGTTCGTCTTCTT
    CACCGTGCTGCCAAGGACCAATTGATTGTTACAGAAAATCTTCCAATCGAGGCAGATGTG
    ACTCACTTTCATACGATTGATTTTCCCTATTATTTATCAACCTTCCAAAAGAAACGCTCA
    GGGAGAAAGATTGGCTATGTGCATTTCTTGCCAGCTACACTTGAGGGAAGTTTGAAAATT
    CCATTTTTCTTAAAGGGAATTGTGAAACGCTATGTATTTTCTTTTTACAACCGGATGGAG
    CACTTGGTTGTGGTCAATCCTATGTTTATTGAGGATTTGGTAGCAGCTGGTATTCCACGT
    GAAAAAGTGACCTATATTCCTAACTTTGTCAACAAGGAAAAATGGCATCCTCTACCACAA
    GAAGAGGTAGTTAGACTGCGCACAGATCTTGGTCTTAGTGACAATCAGTTTATCGTAGTA
    GGTGCTGGGCAAGTTCAGAAACGTAAAGGGATTGATGACTTTATCCGTCTGGCTGAGGAA
    TTGCCTCAGATTACCTTTATCTGGGCTGGTGGCTTCTCTTTTGGTGGTATGACAGATGGT
    TATGAACACTATAAGACAATTATGGAAAATCCCCCTAAAAATTTGATTTTTCCAGGCATT
    GTATCGCCAGAGCGGATGCGCGAATTGTATGCTCTAGCGGATCTTTTCTTGTTGCCTAGT
    TACAATGAGCTCTTTCCTATGACTATTTTAGAAGCTGCGAGTTGTGAGGCTCCTATTATG
    TTGCGTGATTTAGATCTCTATAAGGTGATTTTGGAGGGAAATTATCGGGCGACAGCGGGT
    AGAGAAGAGATGAAAGAGGCTATTTTGGAATATCAAGCAAATCCTGCTGTCTTAAAAGAT
    CTCAAAGAAAAGGCTAAGAATATTTCCAGAGAGTATTCTGAAGAGCATCTGTTACAAATC
    TGGTTGGACTTTTATGAGAAACAAGCCGCTTTAGGGAGAAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1125

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPR_RS04915 [old locus tag: spr0981 ]
  • symbol: CpoA
  • description: alpha-galactosylglucosyldiacylglycerol synthase
  • length: 374
  • theoretical pI: 8.71414
  • theoretical MW: 43092.9
  • GRAVY: -0.114706

⊟Function[edit | edit source]

  • reaction:
    EC 2.4.1.-?  ExPASy
  • TIGRFAM:
    Unknown function Enzymes of unknown specificity glycosyltransferase, MSMEG_0565 family (TIGR04047; HMM-score: 59.2)
    and 8 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA (TIGR03999; EC 2.4.1.-; HMM-score: 44.8)
    glycosyltransferase, GG-Bacteroidales peptide system (TIGR04157; EC 2.4.1.-; HMM-score: 41.3)
    sugar transferase, PEP-CTERM/EpsH1 system associated (TIGR03088; HMM-score: 37.7)
    PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family (TIGR04063; EC 2.4.-.-; HMM-score: 35)
    colanic acid biosynthesis glycosyltransferase WcaI (TIGR04007; EC 2.4.-.-; HMM-score: 33.4)
    D-inositol-3-phosphate glycosyltransferase (TIGR03449; EC 2.4.1.250; HMM-score: 32.6)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen synthase, Corynebacterium family (TIGR02149; HMM-score: 28.5)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen/starch synthase, ADP-glucose type (TIGR02095; EC 2.4.1.21; HMM-score: 11.4)
  • TheSEED: see spr0981
  • PFAM:
    GT-B (CL0113) Glycos_transf_1; Glycosyl transferases group 1 (PF00534; HMM-score: 51.8)
    Glyco_trans_1_4; Glycosyl transferases group 1 (PF13692; HMM-score: 43.1)
    and 3 more
    Glyco_transf_4; Glycosyltransferase Family 4 (PF13439; HMM-score: 30.5)
    Glyco_trans_1_2; Glycosyl transferases group 1 (PF13524; HMM-score: 17.7)
    Glyco_trans_4_4; Glycosyl transferase 4-like domain (PF13579; HMM-score: 15.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0877
    • Cytoplasmic Membrane Score: 0.8704
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.041
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.159572
    • TAT(Tat/SPI): 0.001054
    • LIPO(Sec/SPII): 0.026292
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MRKFPLFSSSLSFLLLILFKENDIIVVMEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLRTDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYKTIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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