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serotype 1

NCBI: 25-NOV-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: SPR_RS06115 [old locus tag: spr1223 ]
  • pan locus tag?: PNEUPAN002641000
  • symbol: SPR_RS06115
  • pan gene symbol?: cps23FU
  • synonym:
  • product: glycosyltransferase family 2 protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPR_RS06115 [old locus tag: spr1223 ]
  • symbol: SPR_RS06115
  • product: glycosyltransferase family 2 protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1220544..1221530
  • length: 987
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGAAACTGCATTAATTAGTGTGATTGTGCCAGTCTATAATGTGGCGCAGTACCTAGAA
    AAATCGATAGCTTCCATTCAGAAGCAGACCTATCAAAATCTGGAAATTATTCTTGTTGAT
    GATGGTGCAACAGATGAAAGTGGTCGCTTGTGTGATTCAATCGCTGAACAAGATGACAGG
    GTGTCAGTGCTTCATAAAAAGAACGAAGGATTGTCGCAAGCACGAAATGATGGGATGAAG
    CAGGCTCACGGGGATTATCTGATTTTTATTGACTCAGATGATTATATCCATCCAGAAATG
    ATTCAGAGCTTATATGAGCAATTAGTTCAAGAAGATGCGGATGTTTCGAGCTGTGGTGTC
    ATGAATGTCTATGCTAATGATGAAAGCCCACAGTCAGCCAATCAGGATGACTATTTTGTC
    TGTGATTCTCAAACATTTCTAAAGGAATACCTCATAGGTGAAAAAATACCTGGGACGATT
    TGCAATAAGCTAATCAAGAGACAGATTGCAACTGACCTATCCTTTCCTAAGGGGTTGATT
    TACGAAGATGCCTATTACCATTTTGATTTAATCAAGTTGGCCAAGAAGTATGTGGTTAAT
    ACTAAACCCTATTATTACTATTTCCATAGAGGGGATAGTATTACGACCAAACCCTATGCA
    GAGAAGGATTTAGCCTATATTGATATCTACCAAAAGTTTTATAATGAAGTTGTGAAAAAC
    TATCCTGACTTGAAAGAGGTCGCTTTTTTCAGATTGGCCTATGCCCACTTCTTTATTCTG
    GATAAGATGTTGCTAGATGATCAGTATAAACAGTTTGAAGCCTATTCTCAGATTCATCGT
    TTTTTAAAAGGCCATGCCTTTGCTATTTCTAGGAATTCAATTTTCCGTAAGGGGAGAAGA
    ATTAGTGCTTTGGCCCTATTCATAAATATTTCCTTATACCGATTCTTATTACTGAAAAAT
    ATTGAAAAATCTAAAAAATTACATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    987

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPR_RS06115 [old locus tag: spr1223 ]
  • symbol: SPR_RS06115
  • description: glycosyltransferase family 2 protein
  • length: 328
  • theoretical pI: 6.24594
  • theoretical MW: 38132.2
  • GRAVY: -0.319207

⊟Function[edit | edit source]

  • reaction:
    EC 2.4.-.-?  ExPASy
  • TIGRFAM:
    poly-beta-1,6 N-acetyl-D-glucosamine synthase (TIGR03937; EC 2.4.1.-; HMM-score: 77.9)
    and 10 more
    putative glycosyltransferase, exosortase G-associated (TIGR03111; HMM-score: 56.5)
    Unknown function Enzymes of unknown specificity transferase 2, rSAM/selenodomain-associated (TIGR04283; EC 2.-.-.-; HMM-score: 54.6)
    mycofactocin system glycosyltransferase (TIGR03965; HMM-score: 53.6)
    colanic acid biosynthesis glycosyltransferase WcaA (TIGR04017; EC 2.4.-.-; HMM-score: 47)
    hopene-associated glycosyltransferase HpnB (TIGR03469; HMM-score: 43.2)
    chitooligosaccharide synthase NodC (TIGR04242; EC 2.4.1.-; HMM-score: 41.7)
    glycosyltransferase domain (TIGR04440; EC 2.-.-.-; HMM-score: 31.1)
    colanic acid biosynthesis glycosyltransferase WcaE (TIGR04009; EC 2.4.-.-; HMM-score: 30.5)
    glycosyltransferase, TIGR04182 family (TIGR04182; HMM-score: 30.4)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides rhamnosyltransferase (TIGR01556; EC 2.4.1.-; HMM-score: 28.7)
  • TheSEED: see spr1223
  • PFAM:
    GT-A (CL0110) Glycos_transf_2; Glycosyl transferase family 2 (PF00535; HMM-score: 125.7)
    and 7 more
    Glyco_tranf_2_2; Glycosyltransferase like family 2 (PF10111; HMM-score: 58.3)
    Glyco_tranf_2_3; Glycosyltransferase like family 2 (PF13641; HMM-score: 58)
    Glyco_tranf_2_4; Glycosyl transferase family 2 (PF13704; HMM-score: 22.8)
    Glyco_tranf_2_5; Glycosyltransferase like family (PF13712; HMM-score: 15.7)
    MGAT2; N-acetylglucosaminyltransferase II (MGAT2) (PF05060; HMM-score: 14.1)
    Glyco_trans_2_3; Glycosyl transferase family group 2 (PF13632; HMM-score: 13)
    Glyco_transf_21; Glycosyl transferase family 21 (PF13506; HMM-score: 11.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0266
    • Cytoplasmic Membrane Score: 0.9382
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.0344
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016348
    • TAT(Tat/SPI): 0.000501
    • LIPO(Sec/SPII): 0.001714
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGATDESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQSLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTICNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKPYAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYSQIHRFLKGHAFAISRNSIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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