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serotype 1

NCBI: 25-NOV-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: SPR_RS09275 [old locus tag: spr1832 ]
  • pan locus tag?: PNEUPAN003652000
  • symbol: SPR_RS09275
  • pan gene symbol?: bguR
  • synonym:
  • product: GntR family transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPR_RS09275 [old locus tag: spr1832 ]
  • symbol: SPR_RS09275
  • product: GntR family transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 1806563..1807291
  • length: 729
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAGTACAAAATATTTATTTATTTACAATGAGATTCGTGAAAAGATTCTTTGTAATAAA
    TATACCATGAACGAACAATTGCCTGATGAAATGACATTAGCTAAACAGTTTGCCTGTAGT
    CGAATGACGATCAAAAAAGCTTTAGACTTGTTAGTTTCTGAGGGCTTAATTTTTAGAAAA
    CGTGGGCAGGGAACCTTTGTTCTCTCTCGTGGCAGCTCAAAAAGAAAATTAATCGTTCCA
    GAAAGAGATATCCGGGGACTGACAAAAATATCTGAAGATGCTCATTCTACAATTGACTCG
    AGGATTATTCACTTCAAATTAGAATTTGCAAATGAATTTTTAGCAGAAAAACTACAGGTC
    GCTTTGCAGAGTCCAGTTTATAATATTTACCGCCTGCGTATTATTGACGGTAAACCTTAT
    GTTCTGGAACAAACTTATATGAGTACCGATGTTATTCCAGGTATTACTGAAGATATTTTA
    CAAAAATCGATTTACAATTACATTGAAGGAAAGTTAGGATTGCATATTGCCAGTGCTACA
    AAAATCTTACGAGCTTCTTCTAGTTCAGAAAATGAGCAACATTACTTGCAGCTCCTTCCA
    ACGGAACCGGTATTTGAAGTAGAACAAGTGGCTTATTTGGATAACGGAACTCCGTTTGAG
    TACTCGATTAGTCGTCATCGCTATGATTTATTTGAATTTAATTCTTTTGCATTACGACAT
    TCCTCCTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    729

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPR_RS09275 [old locus tag: spr1832 ]
  • symbol: SPR_RS09275
  • description: GntR family transcriptional regulator
  • length: 242
  • theoretical pI: 8.18396
  • theoretical MW: 27992
  • GRAVY: -0.279752

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions trehalose operon repressor (TIGR02404; HMM-score: 169.5)
    and 7 more
    Metabolism Transport and binding proteins Anions phosphonate metabolism transcriptional regulator PhnF (TIGR02325; HMM-score: 104.4)
    Signal transduction Regulatory functions DNA interactions phosphonate metabolism transcriptional regulator PhnF (TIGR02325; HMM-score: 104.4)
    Metabolism Energy metabolism Amino acids and amines histidine utilization repressor (TIGR02018; HMM-score: 94)
    Signal transduction Regulatory functions DNA interactions histidine utilization repressor (TIGR02018; HMM-score: 94)
    Signal transduction Regulatory functions DNA interactions phosphonate utilization transcriptional regulator PhnR (TIGR03337; HMM-score: 93.1)
    phosphonate utilization associated transcriptional regulator (TIGR03338; HMM-score: 16.3)
    type-F conjugative transfer system pilin chaperone TraQ (TIGR02741; HMM-score: 12.1)
  • TheSEED: see spr1832
  • PFAM:
    UTRA (CL0122) UTRA; UTRA domain (PF07702; HMM-score: 124)
    and 6 more
    HTH (CL0123) GntR; Bacterial regulatory proteins, gntR family (PF00392; HMM-score: 69.4)
    HTH_11; HTH domain (PF08279; HMM-score: 18.5)
    HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 16.9)
    HTH_41; Helix-turn-helix domain (PF14502; HMM-score: 16)
    MarR; MarR family (PF01047; HMM-score: 15)
    HTH_DeoR; DeoR-like helix-turn-helix domain (PF08220; HMM-score: 11.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9916
    • Cytoplasmic Membrane Score: 0.0053
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0031
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002833
    • TAT(Tat/SPI): 0.000163
    • LIPO(Sec/SPII): 0.00051
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTIKKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRIIHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDILQKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTPFEYSISRHRYDLFEFNSFALRHSS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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