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serotype 4
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serotype 2
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serotype 19A
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HU-OH
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Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_0608 [new locus tag: SPT_RS03030 ]
  • pan locus tag?: PNEUPAN001470000
  • symbol: SPT_0608
  • pan gene symbol?: bglA-2
  • synonym:
  • product: beta-glucosidase (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase) (Amygdalase)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_0608 [new locus tag: SPT_RS03030 ]
  • symbol: SPT_0608
  • product: beta-glucosidase (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase) (Amygdalase)
  • replicon: chromosome
  • strand: +
  • coordinates: 566546..567961
  • length: 1416
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGACCATTTTTCCAGATGATTTTCTTTGGGGTGGAGCGGTTGCAGCTAATCAAGTAGAG
    GGAGCATATAATGAAGATGGTAAGGGATTATCAGTTCAGGATGTGTTACCCAAAGGTGGA
    TTAGGAGAAGCAACAGAAAATCCTACAGAAGATAACTTAAAATTGTTAGGTATTGATTTT
    TATCATAAATATAAGGAAGATATATCCTTGTTTTCTGAAATGGGCTTTAATGTTTTTCGT
    ACTTCTATTGCATGGAGTAGAATTTTTCCAAAAGGAGATGAAGAAGAACCTAACGAAGCT
    GGGTTGAAATATTATGATGAATTATTTGATGAACTACATGCTCACGGGATAGAACCACTT
    GTAACTCTTTCACACTATGAGACTCCATTATATTTAGCAAGAAAATATCATGGATGGATT
    GATAGGAGAATGATTCATTTTTATGAAAAATTTGCTCGAACAGTTTTAGAAAGGTATAAA
    GATAAAGTTAAATATTGGCTTACATTTAACGAAGTAAACTCTGTTTTGGAATTACCGTTT
    ACTAGTGGAGGAATAGATATACCTAAGGAGAATCTTTCGAAACAAGAATTATATCAAGCT
    ATACATCATGAATTAGTCGCCTCGAGTTTGGTTACAAAAATTGCTCGTGAGATTAATTCA
    GAGTTTAAGGTGGGGTGTATGGTATTAGCTATGCCAGCTTATCCAATGACTCCAAATCCA
    AAAGATGTATGGGCGACTCATGAGTATGAGAATCTAAATTATCTATTTTCAGATGTGCAT
    GTTAGAGGTTATTATCCGAATTATGCAAAAAGATATTTTAAGGAACATGACATTAACATA
    GAGTTTGCAGCTGAAGATGCAGAGTTATTAAAAAATTATACTGTAGATTTTTTATCCTTT
    AGCTATTACATGAGTGTGACTCAATCTGCTCTTCCAACACAGTATAATTCAGGAGAAGGG
    AATATTATTGGTGGCTTAGTAAATCCTTATTTAGAGTCTTCTGAGTGGGGATGGCAAATT
    GATCCAATTGGACTACGTATAATTTTAAATAGATATTATGACCGTTATCAAATTCCATTA
    TTTATAGTGGAAAACGGATTAGGTGCTAAAGATCAACTAATAAAAGATGAATTTAATAAC
    TTAACAGTCCAAGATGATTATAGAATTCAGTATATGGAAGAACATTTATTGCAAGTAGCT
    GAAGCTCTACAAGATGGTGTGGAAATTATGGGCTATACATCTTGGGGATGTATTGACTGC
    GTTTCTATGTCCACTGCACAACTTTCTAAAAGGTACGGTCTCATTTATGTTGATCGAAAT
    GATGATGGAAATGGCACATTCAATCGATATAAGAAAATGTCCTTTACTTGGTATAAAGGA
    GTGATTGAATCAAATGGAGAATCCTTATTCAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1416

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_0608 [new locus tag: SPT_RS03030 ]
  • symbol: SPT_0608
  • description: beta-glucosidase (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase) (Amygdalase)
  • length: 471
  • theoretical pI: 4.62307
  • theoretical MW: 54421.9
  • GRAVY: -0.403609

⊟Function[edit | edit source]

  • reaction:
    EC 3.2.1.21?  ExPASy
    Beta-glucosidase Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose
  • TIGRFAM:
    beta-galactosidase (TIGR03356; HMM-score: 293.8)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides 6-phospho-beta-galactosidase (TIGR01233; EC 3.2.1.85; HMM-score: 239.6)
  • TheSEED  :
    • 6-phospho-beta-glucosidase (EC 3.2.1.86)
    Carbohydrates Di- and oligosaccharides Beta-Glucoside Metabolism  6-phospho-beta-glucosidase (EC 3.2.1.86)
  • PFAM:
    Glyco_hydro_tim (CL0058) Glyco_hydro_1; Glycosyl hydrolase family 1 (PF00232; HMM-score: 451.1)
    and 1 more
    Cellulase; Cellulase (glycosyl hydrolase family 5) (PF00150; HMM-score: 25.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8701
    • Cytoplasmic Membrane Score: 0.0015
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.1274
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.024089
    • TAT(Tat/SPI): 0.005806
    • LIPO(Sec/SPII): 0.006271
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO23958 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEATENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGLKYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYKDKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREINSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEHDINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESSEWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYMEEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRYKKMSFTWYKGVIESNGESLFK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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