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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_0618 [new locus tag: SPT_RS03085 ]
  • pan locus tag?: PNEUPAN001485000
  • symbol: cysE
  • pan gene symbol?: cysE
  • synonym:
  • product: serine O-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_0618 [new locus tag: SPT_RS03085 ]
  • symbol: cysE
  • product: serine O-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 580955..581572
  • length: 618
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGGGGTGGTGGCGCGAAACCATTGATATCGTAAAAGAAAATGATCCAGCGGCCCGCACC
    ACTTTGGAGGTTTTGCTGACTTATCCAGGTGTCAAGGCCTTGGCGGCCCACCGTCTCTCG
    CATTTTCTCTGGAAGCACAGCTTCAAACTCTTAGCTCGTATGCACAGTCAGTTTTGGCGC
    TTTTGGACTCAGATTGAGATTCATCCAGGAGCCCAGATTGATTCAGGTGTCTTTATTGAC
    CATGGTTCTGGTCTGGTGATTGGAGAGACAGCGATTGTTGAAAAAGGCGTTCTTCTCTAT
    CACGGAGTGACTCTTGGGGGAACAGGGAAAGACTGTGGCAAACGCCATCCGACTGTACGA
    AAGGGAGCCCTCATATCAGCCCATGCCCAAGTTATCGGACCTGTGGAAATTGGTGAAAAT
    GCCAAGGTCGGTGCTGCAGCAGTTGTCGTAGCAGATGTACCTAGTGATGTGACGGTTGTC
    GGTATTCCGGCCAAGATTGTCCGTCTTCATGGTAAGAAAGATGAGCCTGTTATTCACGCA
    GTCGAAGAAAAACGAGAGTATTATGTCAATAAACTCGAGCAGGCTAAAGATGCCAGTCAC
    AGATCGTCTGGTTTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    618

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_0618 [new locus tag: SPT_RS03085 ]
  • symbol: CysE
  • description: serine O-acetyltransferase
  • length: 205
  • theoretical pI: 9.40519
  • theoretical MW: 22426.7
  • GRAVY: -0.0765854

⊟Function[edit | edit source]

  • reaction:
    EC 2.3.1.30?  ExPASy
    Serine O-acetyltransferase Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine
  • TIGRFAM:
    Metabolism Amino acid biosynthesis Serine family serine O-acetyltransferase (TIGR01172; EC 2.3.1.30; HMM-score: 230.9)
    and 14 more
    sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family (TIGR03570; HMM-score: 48.1)
    colanic acid biosynthesis acetyltransferase WcaB (TIGR04016; EC 2.3.1.-; HMM-score: 43.9)
    2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (TIGR03532; EC 2.3.1.89; HMM-score: 40.8)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (TIGR01853; EC 2.3.1.191; HMM-score: 28.1)
    Metabolism Energy metabolism Other phenylacetic acid degradation protein PaaY (TIGR02287; HMM-score: 25.6)
    phosphonate metabolim protein, transferase hexapeptide repeat family (TIGR03308; HMM-score: 23.3)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 20.6)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 20.6)
    Metabolism Central intermediary metabolism Amino sugars UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 20.6)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR03991; EC 2.3.1.157,2.7.7.23; HMM-score: 17.2)
    Metabolism Central intermediary metabolism Amino sugars UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR03991; EC 2.3.1.157,2.7.7.23; HMM-score: 17.2)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase (TIGR01852; EC 2.3.1.129; HMM-score: 16.4)
    UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR03992; EC 2.3.1.157,2.7.7.23; HMM-score: 15.3)
    colanic acid biosynthesis acetyltransferase WcaF (TIGR04008; EC 2.3.1.-; HMM-score: 12.4)
  • TheSEED  :
    • Serine acetyltransferase (EC 2.3.1.30)
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Cysteine Biosynthesis  Serine acetyltransferase (EC 2.3.1.30)
    and 2 more
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis  Serine acetyltransferase (EC 2.3.1.30)
    Miscellaneous Plant-Prokaryote comparative genomics Conserved gene cluster possibly involved in RNA metabolism  Serine acetyltransferase (EC 2.3.1.30)
  • PFAM:
    HEXAPEP (CL0536) Hexapep; Bacterial transferase hexapeptide (six repeats) (PF00132; HMM-score: 35.4)
    and 1 more
    Hexapep_2; Hexapeptide repeat of succinyl-transferase (PF14602; HMM-score: 13.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.5713
    • Cytoplasmic Membrane Score: 0.3629
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0655
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002555
    • TAT(Tat/SPI): 0.002132
    • LIPO(Sec/SPII): 0.00076
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO22819 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLWKHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHGVTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVVGIPAKIVRLHGKKDEPVIHAVEEKREYYVNKLEQAKDASHRSSGL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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