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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_1709 [new locus tag: SPT_RS08500 ]
  • pan locus tag?: PNEUPAN003248000
  • symbol: SPT_1709
  • pan gene symbol?: —
  • synonym:
  • product: ATPase of the AAA+ class

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_1709 [new locus tag: SPT_RS08500 ]
  • symbol: SPT_1709
  • product: ATPase of the AAA+ class
  • replicon: chromosome
  • strand: -
  • coordinates: 1627380..1628252
  • length: 873
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGCCACAAATAGAAAATCCTAGTGAGTATTTGACTCCTGCTAAACTAGATATTGGTCCT
    CTCCCATTGCCTCTTTCAATTATGAATGATTTAAAAGGAATAATAAACGCTGTCAATCAT
    CATATTGGAATAAATAAATTTTTATTTGTGGGATCTCCAGGTACTGGAAAAACTGAAAGT
    GTAAAGCAGGTGGCTAGACTTATTGGCAAGGAATTACTTGTAGTAGATTTCAGTCACTTA
    GTAGATAGTAAGCTAGGGCAAACAGTCAAAAACTTAGCAACTCTTTTTAATGAAATCAAT
    AATCTTCCTTTCAAGCAAAATTATATCATCCTATTTGATGAAATTGATTCCATAGTGTTG
    GATAGGGTTAATCAGAATGATTTAAGAGAAATGGGACGAGTGACTTCTGCCTTTTTAAAG
    GAGTTGGATAGGCTGTCACCAGAAATTGTATTAATTGCAACAACAAATCTTTTTGAAAAT
    CTTGATAAAGCAGTTACGAGAAGATTCGATGCCATAATTGACTTTGACCGTTATACTGAT
    GAAGATAAAGTAGAAGTAGCTACTATTATTTTAAATGAGTTATTAAAGCAATTTAAGAAT
    GTAGCTAGAGATTTAAAATTATTTAAAAAAATTATCAATAGTGCCAATGTAATACCGAAT
    CCTGGTGATTTGAGAAACTCAATAAGAACGTCATTGGCATTTAGTGATCCATCAGATCCG
    CATGATTACCAAAAACGCCTGCTAAGAAGTTTGCATAATGGTAGAAATTTATCTATTTCT
    AAATTATCGAAGCTAGGTTTTACTGTTAGAGAAATTGAGATTTTGACAGGTGTTTCTAAG
    AGTAGTGTATCACGAGAGTTAAGCGAGGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    873

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_1709 [new locus tag: SPT_RS08500 ]
  • symbol: SPT_1709
  • description: ATPase of the AAA+ class
  • length: 290
  • theoretical pI: 7.09772
  • theoretical MW: 32633.3
  • GRAVY: -0.165862

⊟Function[edit | edit source]

  • TIGRFAM:
    26S proteasome subunit P45 family (TIGR01242; HMM-score: 43.6)
    AAA family ATPase, CDC48 subfamily (TIGR01243; HMM-score: 42.2)
    Cellular processes Cellular processes Cell division ATP-dependent metallopeptidase HflB (TIGR01241; EC 3.4.24.-; HMM-score: 36.6)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides ATP-dependent metallopeptidase HflB (TIGR01241; EC 3.4.24.-; HMM-score: 36.6)
    and 7 more
    Cellular processes Cellular processes Sporulation and germination stage V sporulation protein K (TIGR02881; HMM-score: 26.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion AAA-ATPase EccA (TIGR03922; HMM-score: 24.3)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides ATP-dependent Clp protease ATP-binding subunit ClpA (TIGR02639; HMM-score: 23.5)
    CbbX protein (TIGR02880; HMM-score: 19.3)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair orc1/cdc6 family replication initiation protein (TIGR02928; HMM-score: 18.1)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair Holliday junction DNA helicase RuvB (TIGR00635; EC 3.6.4.12; HMM-score: 14.6)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides endopeptidase La (TIGR00763; EC 3.4.21.53; HMM-score: 13.8)
  • TheSEED  :
    • AAA superfamily ATPase
  • PFAM:
    P-loop_NTPase (CL0023) AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 91.6)
    and 18 more
    AAA_2; AAA domain (Cdc48 subfamily) (PF07724; HMM-score: 27.9)
    AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 25.4)
    AAA_6; Hydrolytic ATP binding site of dynein motor region (PF12774; HMM-score: 23.2)
    AAA_24; AAA domain (PF13479; HMM-score: 19.1)
    AAA_14; AAA domain (PF13173; HMM-score: 18.8)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 17.4)
    AAA_3; ATPase family associated with various cellular activities (AAA) (PF07726; HMM-score: 17.3)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 16.2)
    AAA_28; AAA domain (PF13521; HMM-score: 15.5)
    AAA_33; AAA domain (PF13671; HMM-score: 14.4)
    AAA_19; AAA domain (PF13245; HMM-score: 13.9)
    AAA_7; P-loop containing dynein motor region (PF12775; HMM-score: 13.8)
    DUF815; Protein of unknown function (DUF815) (PF05673; HMM-score: 13.6)
    AAA_18; AAA domain (PF13238; HMM-score: 12.7)
    TPR (CL0020) Proteasom_PSMB; Proteasome non-ATPase 26S subunit (PF10508; HMM-score: 12.4)
    P-loop_NTPase (CL0023) AAA_22; AAA domain (PF13401; HMM-score: 12)
    AAA_30; AAA domain (PF13604; HMM-score: 11.9)
    Mg_chelatase; Magnesium chelatase, subunit ChlI (PF01078; HMM-score: 11.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011342
    • TAT(Tat/SPI): 0.000237
    • LIPO(Sec/SPII): 0.000302
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO22692 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFLFVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQNYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKAVTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPGDLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGVSKSSVSRELSED

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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