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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 17-DEC-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae Taiwan19F-14
- locus tag: SPT_RS00205 [old locus tag: SPT_0039 ]
- pan locus tag?: PNEUPAN000360000
- symbol: pth
- pan gene symbol?: pth
- synonym:
- product: aminoacyl-tRNA hydrolase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPT_RS00205 [old locus tag: SPT_0039 ]
- symbol: pth
- product: aminoacyl-tRNA hydrolase
- replicon: chromosome
- strand: +
- coordinates: 24663..25232
- length: 570
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NC_012469 (24663..25232) NCBI
- BioCyc: SPT_RS00205 BioCyc
- MicrobesOnline: see SPT_0039
- PneumoBrowse for strain D39V: SPV_0005 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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541ATGACCAAATTACTTGTAGGCTTGGGAAATCCAGGGGATAAATATTTTGAAACAAAACAC
AATGTTGGTTTTATGTTGATTGATCAACTAGCGAAGAAACAGAATGTCACTTTTACACAC
GATAAGATATTTCAAGCTGACCTAGCATCCTTTTTCCTAAATGGAGAAAAAATTTATCTG
GTTAAACCAACGACCTTTATGAATGAAAGTGGAAAAGCAGTTCATGCTTTATTAACTTAC
TATGGTTTGGATATTGACGATTTACTTATCATTTACGATGATCTTGACATGGAAGTTGGG
AAAATTCGTTTAAGAGCAAAAGGCTCAGCAGGTGGTCATAATGGTATCAAGTCTATTATT
CAACATATAGGAACTCAGGTCTTTAACCGTGTTAAGATTGGAATTGGAAGACCTAAAAAT
GGTATGTCAGTTGTTCATCATGTTTTGAGTAAGTTTGACAGGGATGAGTATATCGGTATT
TTACAGTCTGTTGACAAAGTTGACGATTCTGTAAACTACTATTTACAAGAGAAAAATTTT
GAGAAAACAATGCAGAGGTATAACGGATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPT_RS00205 [old locus tag: SPT_0039 ]
- symbol: Pth
- description: aminoacyl-tRNA hydrolase
- length: 189
- theoretical pI: 9.12807
- theoretical MW: 21404.5
- GRAVY: -0.279365
⊟Function[edit | edit source]
- reaction: EC 3.1.1.29? ExPASyAminoacyl-tRNA hydrolase N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA
- TIGRFAM: Protein synthesis Other aminoacyl-tRNA hydrolase (TIGR00447; EC 3.1.1.29; HMM-score: 216.8)
- TheSEED: see SPT_0039
- PFAM: no clan defined Pept_tRNA_hydro; Peptidyl-tRNA hydrolase (PF01195; HMM-score: 220.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.67
- Cytoplasmic Membrane Score: 0.01
- Cellwall Score: 0.15
- Extracellular Score: 0.17
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9861
- Cytoplasmic Membrane Score: 0.0053
- Cell wall & surface Score: 0.0002
- Extracellular Score: 0.0084
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001635
- TAT(Tat/SPI): 0.000083
- LIPO(Sec/SPII): 0.000244
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIFQADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKIRLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGILQSVDKVDDSVNYYLQEKNFEKTMQRYNG
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: ychF > pth > mfd > SPT_RS00215 > SPT_RS00220 > SPT_RS13195 > SPT_RS00230 > tilS > hpt > ftsH
⊟Regulation[edit | edit source]
- regulator: RegR* see SPT_0039
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0005 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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