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serotype 4
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D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
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70585
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BM6001
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serotype 14
G54
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HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
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SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_RS01950 [old locus tag: SPT_0387 ]
  • pan locus tag?: PNEUPAN001092000
  • symbol: mraY
  • pan gene symbol?: mraY
  • synonym:
  • product: phospho-N-acetylmuramoyl-pentapeptide- transferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_RS01950 [old locus tag: SPT_0387 ]
  • symbol: mraY
  • product: phospho-N-acetylmuramoyl-pentapeptide- transferase
  • replicon: chromosome
  • strand: +
  • coordinates: 347252..348232
  • length: 981
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGTTTATTTCTATTAGTGCTGGAATTGTGACATTTTTACTAACTTTAGTAGGAATTCCG
    GCCTTTATCCAATTTTATAGAAAGGCGCAAATTACAGGCCAGCAGATGCATGAGGATGTT
    AAACAGCACCAGGCAAAAGCTGGGACTCCTACAATGGGGGGACTTGTTTTCCTCATTGCT
    GCAGTTGTGGTGAGTTTCCTCGTCGCTCTTTTTTCGAAACAATTGACCAATAATGTTGGT
    ATGATTTTGTTTATTTTGGTCTTGTATGGCTTGGTTGGTTTTTTAGATGACTTTCTCAAG
    GTCTTCCGAAAGATCAATGAGGGGCTAAACCCCAAACAGAAATTGGCTCTTCAGCTGCTA
    GGTGGCGTCATTTTCTACCTTTTTTATGAGCGTGGGGGCGATATGCTCTCTGTCTTTGGC
    TACCAAGTGCATTTAGGGATTTTCTATATTATCTTCGCTCTTTTCTGGCTAGTTGGTTTT
    TCAAACGCAGTCAACTTGACAGATGGTATTGACGGTCTAGCTAGTATTTCCGTTGTGATT
    AGTTTGTCTGCCTATGGAGTTATTGCCTATGTGCAAGGCCAGATGGATATTCTCCTGGTG
    ATTTTTGCCATGATTGGTGGTTTGCTTGGTTTCTTCGTCTTTAACCACAAGCCTGCCAAG
    GTCTTTATGGGAGATGTGGGAAGTTTGGCTCTCGGTGGAATGCTGGCAGCTATCTCTATG
    GCCCTCCACCAAGAATGGACTCTCTTGATTATCGGAATTGTGTATGTTTTTGAAACAACT
    TCGGTCATGATGCAAGTCAGCTATTTCAAACTGACAGGTGGTAAACGTATTTTCCGTATG
    ACGCCTGTACATCACCATTTTGAGCTTGGGGGATTGTCTGGTAAAGGAAATCCTTGGAGC
    GAGTGGAAGGTTGACTTCTTCTTTTGGGGAGTTGGGCTTCTAGCAAGTCTCCTGACCTTC
    GCAATTTTGTATTTGATGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    981

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_RS01950 [old locus tag: SPT_0387 ]
  • symbol: MraY
  • description: phospho-N-acetylmuramoyl-pentapeptide- transferase
  • length: 326
  • theoretical pI: 9.35391
  • theoretical MW: 35946.6
  • GRAVY: 0.865337

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.8.13?  ExPASy
    Phospho-N-acetylmuramoyl-pentapeptide-transferase UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan phospho-N-acetylmuramoyl-pentapeptide-transferase (TIGR00445; EC 2.7.8.13; HMM-score: 267.6)
    and 2 more
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase (TIGR02380; EC 2.7.8.33; HMM-score: 53.3)
    TIGR03943 family protein (TIGR03943; HMM-score: 5.8)
  • TheSEED: see SPT_0387
  • PFAM:
    no clan defined Glycos_transf_4; Glycosyl transferase family 4 (PF00953; HMM-score: 130.3)
    and 3 more
    MraY_sig1; Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 (PF10555; HMM-score: 25.3)
    PRA1; PRA1 family protein (PF03208; HMM-score: 7)
    DUF2070; Predicted membrane protein (DUF2070) (PF09843; HMM-score: 4.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9999
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0001
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02145
    • TAT(Tat/SPI): 0.000801
    • LIPO(Sec/SPII): 0.023376
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLIAAVVVSFLVALFSKQLTNNVGMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIIFALFWLVGFSNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVIFAMIGGLLGFFVFNHKPAKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTFAILYLM

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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