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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
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70585
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A026
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AP200
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ATCC 700669
serotype 23F
BM6001
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CGSP14
serotype 14
G54
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HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
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SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_RS05120 [old locus tag: SPT_1036 ]
  • pan locus tag?: PNEUPAN002431000
  • symbol: lacD
  • pan gene symbol?: lacD
  • synonym:
  • product: tagatose-bisphosphate aldolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_RS05120 [old locus tag: SPT_1036 ]
  • symbol: lacD
  • product: tagatose-bisphosphate aldolase
  • replicon: chromosome
  • strand: +
  • coordinates: 975573..976553
  • length: 981
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCTTTAACAGAACAAAAACGTGCACGCTTAGAAAAACTTTCTGATGAAAATGGTATC
    ATCTCAGCTCTTGCATTTGACCAACGTGGTGCTTTGAAACGCCTCATGGCTCAACACCAA
    ACAGAAGAACCAACTGTGGCTCAAATGGAAGAACTGAAAGTCTTGGTAGCAGATGAATTG
    ACTAAATACGCTTCATCAATGCTTCTTGACCCTGAGTATGGACTTCCAGCAACTAAAGCT
    CTTGATGAAAAAGCTGGTCTTCTCCTTGCTTATGAAAAAACAGGTTATGACACAACAAGT
    ACAAAACGCTTGCCAGACTGCTTGGATGTTTGGTCTGCAAAACGTATTAAAGAAGAGGGT
    GCAGATGCAGTTAAATTCTTGCTTTACTATGATGTAGATAGTTCAGACGAACTCAACCAA
    GAAAAACAAGCTTATATCGAGCGTATCGGTTCTGAGTGTGTGGCTGAAGATATCCCATTC
    TTCCTTGAAATCCTTGCTTACGATGAAAAAATTGCAGACGCAGGTTCTGTAGAATATGCG
    AAAGTAAAACCACACAAAGTTATCGGTGCTATGAAAGTCTTTTCAGACCCACGCTTTAAC
    ATTGATGTCTTGAAAGTTGAAGTTCCTGTTAACATTAAATATGTTGAAGGCTTCGCTGAA
    GGTGAAGTGGTTTACACACGTGAAGAAGCAGCAGCCTTCTTCAAAGCGCAAGATGAAGCA
    ACGAACTTGCCATACATTTACTTGAGTGCTGGTGTATCAGCTAAACTCTTCCAAGATACT
    CTTGTATTTGCTCATGAATCAGGTGCAAACTTTAACGGAGTTCTTTGTGGCCGTGCTACA
    TGGGCAGGATCAGTTGAAGCTTACATCAAAGATGGTGAAGCAGCAGCTCGCGAATGGCTT
    CGCACAACTGGATTTGAAAACATTGATGAGCTCAATAAAGTTCTTCAAACAACAGCGACT
    TCATGGAAAGAACGTGTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    981

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_RS05120 [old locus tag: SPT_1036 ]
  • symbol: LacD
  • description: tagatose-bisphosphate aldolase
  • length: 326
  • theoretical pI: 4.47038
  • theoretical MW: 36357.9
  • GRAVY: -0.26411

⊟Function[edit | edit source]

  • reaction:
    EC 4.1.2.40?  ExPASy
    Tagatose-bisphosphate aldolase D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate
  • TIGRFAM:
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides tagatose 1,6-diphosphate aldolase (TIGR01232; EC 4.1.2.40; HMM-score: 671.2)
  • TheSEED: see SPT_1036
  • PFAM:
    TIM_barrel (CL0036) DeoC; DeoC/LacD family aldolase (PF01791; HMM-score: 224.3)
    and 1 more
    DUF2090; Uncharacterized protein conserved in bacteria (DUF2090) (PF09863; HMM-score: 22.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.965
    • Cytoplasmic Membrane Score: 0.0029
    • Cell wall & surface Score: 0.0012
    • Extracellular Score: 0.0309
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001913
    • TAT(Tat/SPI): 0.00045
    • LIPO(Sec/SPII): 0.000287
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001229114 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MALTEQKRARLEKLSDENGIISALAFDQRGALKRLMAQHQTEEPTVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTKRLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPFFLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGFAEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLCGRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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