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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-NOV-2021

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_RS10765 [old locus tag: SPT_2174 ]
  • pan locus tag?: PNEUPAN003831000
  • symbol: SPT_RS10765
  • pan gene symbol?: manZ_4
  • synonym:
  • product: PTS system mannose/fructose/sorbose family transporter subunit IID

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPT_RS10765 [old locus tag: SPT_2174 ]
  • symbol: SPT_RS10765
  • product: PTS system mannose/fructose/sorbose family transporter subunit IID
  • replicon: chromosome
  • strand: -
  • coordinates: 2029595..2030395
  • length: 801
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_012469 (2029595..2030395) NCBI
  • BioCyc: SPT_RS10765 BioCyc
  • MicrobesOnline: see SPT_2174
  • PneumoBrowse for strain D39V: SPV_1989 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGATGAATAATAAAGTAACTAAAGTTGAACTTAAAAAAGTTTTCAAACGAAGTTTTATG
    TATGGTTCTTCATGGAACTATGAGAGAATGCAGAACCTAGGTTTTCTATATACAATTCTT
    CCAGTATTGAAAAAACTATACCCAGACAAAGATTCAGCTTCTCCTGCAATGAAACGTCAC
    CTTGAGTTTTTCAATACTCATCAAACAGCGGCACCATTTATTCTTGGAGTTACTTCCGCT
    ATGGAAGAACAAGAAGGAAATGAAGGTGCAGCTTCAATTACTGGTATTAAAGTTGGCTTG
    ATGGGGCCGCTGGCTGGTCTAGGAGATAGTTTGTTCTGGCTGACACTAGTTCCTATCTGT
    TTTAGTATTGGTGCGTCTTATTCTAAAGACGGCGGTGCTTTAGGTATCTTTATCGCCTTA
    ATATTGTTTAATATTATTAATATTCCTGTTAAATATTTCGGTTTGAAATATGGGTATACT
    AAGGGTTCTAGTCTTATCCAAGAAAATAATACAAAAGGAACATTGAATCGCGTTACGAGT
    ATGGCGACAGCATTAGGGCTAGTACTAGTGGGTGGTTTGATTCCATCAATGGTTGGTATT
    AATTTTGGATTAGAATTTAAACAGGGGGAACTTGTTATTTCTGTTCAAGAAATGATTACA
    AAATTAATTCCAGGATTTATCCCTATGGCTTTGACTTTATTAATGTGTAAATTAATTAGA
    AAAGGAAAGAATCCGGTTGTACTAATCTTTAGTGTTATGGCTATTGGAGTTATCCTAGTT
    GTTTTAGGAATTTTGAAGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    801

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPT_RS10765 [old locus tag: SPT_2174 ]
  • symbol: SPT_RS10765
  • description: PTS system mannose/fructose/sorbose family transporter subunit IID
  • length: 266
  • theoretical pI: 10.1482
  • theoretical MW: 28981.5
  • GRAVY: 0.486842

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, mannose/fructose/sorbose family, IID component (TIGR00828; HMM-score: 253.7)
    Signal transduction Signal transduction PTS PTS system, mannose/fructose/sorbose family, IID component (TIGR00828; HMM-score: 253.7)
  • TheSEED: see SPT_2174
  • PFAM:
    no clan defined EIID-AGA; PTS system mannose/fructose/sorbose family IID component (PF03613; HMM-score: 308.8)
    and 1 more
    DUF5684; Family of unknown function (DUF5684) (PF18936; HMM-score: 9.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008827
    • TAT(Tat/SPI): 0.000698
    • LIPO(Sec/SPII): 0.001083
  • predicted transmembrane helices (TMHMM): 5

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000981721 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLKKLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMGPLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYTKGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEMITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]