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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 06-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39V
  • locus tag: SPV_0094 [new locus tag: SPV_RS00505 ]
  • pan locus tag?: PNEUPAN000733000
  • symbol: ptvB
  • pan gene symbol?: ptvB
  • synonym:
  • product: Putative membrane-associated protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPV_0094 [new locus tag: SPV_RS00505 ]
  • symbol: ptvB
  • product: Putative membrane-associated protein
  • replicon: chromosome
  • strand: -
  • coordinates: 95301..96212
  • length: 912
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP027540 (95301..96212) NCBI
  • BioCyc: SPV_0094 BioCyc
  • MicrobesOnline:
  • PneumoBrowse: SPV_0094 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGCGTAAATGGACAAAAGGATTTCTCATCTTTGGTGTGGTGACTACCGTTATCGGCTTT
    ATCCTGCTTTTTGTAGGTATCCAATCTGACGGGATTAAGAGCCTACTTTCCATGTCCAAA
    GAACCTGTCTATGATAGCCGTACGGAAAAGCTAACCTTTGGCAAGGAAGTCGAAAACCTA
    GAAATTACTCTCCACCAACACACGCTCACCATCACAGACTCTTTCGATGATCAAATCCAC
    ATTTCTTACCATCCATCTCTTTCTGCTCACCATGATCTTATCACCAATCAGAACGATAGA
    ACTCTGAGTCTCACTGATAAGAAACTGTCTGAAACTCCGTTTCTCTCTTCTGGAATTGGT
    GGGATTCTTCATATCGCAAGTAGCTACTCTAGTCGTTTTGAAGAAGTTATTCTCCGACTA
    CCAAAAGGGAGAACTCTAAAAGGGATCAACATCTCAGCCAATCGCGGACAAACCACCATC
    ATAAATGCTAGCCTTGAAAATGCGACCCTCAATACAAACAGCTATATCCTCCGAATTGAA
    GGAAGTCGTATCAAAAACAGTAAACTCACAACGCCCAATATCGTTAATATCTTTGATACA
    GTTCTTACAGATAGTCAGCTAGAGTCAACAGAGAATCACTTCCACGCTGAAAATATCCAA
    GTCCATGGTAAGGTTGAACTGACTGCCAAAGATTATCTCAGAATCATCCTAGACCAGAAA
    GAAAGCCAACGAATTAACTGGGACATCTCAAGCAACTATGGTTCTATCTTCCAATTCACA
    AGAGAAAAGCCTGAATCAAGAGGTACGGAATTAAGCAACCCTTACAAAACTGAAAAAACC
    GATGTCAAGGATCAACTCATTGCGAGATCTGATGATAATATTGATCTAATATCCACACCA
    AGCAGACGTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    912

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPV_0094 [new locus tag: SPV_RS00505 ]
  • symbol: PtvB
  • description: Putative membrane-associated protein
  • length: 303
  • theoretical pI: 7.09916
  • theoretical MW: 34237.4
  • GRAVY: -0.40231

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Pec_lyase-like (CL0268) DUF4097; Putative adhesin (PF13349; HMM-score: 131.3)
    and 4 more
    no clan defined RnlA_toxin; RNase LS, bacterial toxin (PF15935; HMM-score: 14.8)
    OB (CL0021) FbpC_C_terminal; FbpC C-terminal regulatory nucleotide binding domain (PF17845; HMM-score: 13.7)
    no clan defined DUF2541; Protein of unknown function (DUF2541) (PF10807; HMM-score: 13.6)
    TMEM238; TMEM238 protein family (PF15125; HMM-score: 13.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0011
    • Cytoplasmic Membrane Score: 0.6359
    • Cell wall & surface Score: 0.002
    • Extracellular Score: 0.361
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.39327
    • TAT(Tat/SPI): 0.001838
    • LIPO(Sec/SPII): 0.045726
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AVN85266 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVYDSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTLSLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAENIQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: PtvR/YwzG (repression) regulon
    PtvR/YwzG(TF)important in Transport;  – regulation transferred from D39 see SPD_0094

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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