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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 06-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39V
  • locus tag: SPV_1091 [new locus tag: SPV_RS05830 ]
  • pan locus tag?: PNEUPAN002473000
  • symbol: niaX
  • pan gene symbol?: niaX
  • synonym:
  • product: Substrate-specific component NiaX of putative niacin ECF transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPV_1091 [new locus tag: SPV_RS05830 ]
  • symbol: niaX
  • product: Substrate-specific component NiaX of putative niacin ECF transporter
  • replicon: chromosome
  • strand: +
  • coordinates: 1121837..1122364
  • length: 528
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP027540 (1121837..1122364) NCBI
  • BioCyc: SPV_1091 BioCyc
  • MicrobesOnline:
  • PneumoBrowse: SPV_1091 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    GTGAATACACGGAAAAAGACACAATTTATGACAATGACAGCCCTTTTAACGGCTATTGCG
    ATTTTGATTCCAATTGTTATGCCTTTCAAGATTGTCATTCCACCTGCTTCCTATACTTTG
    GGGAGCCACATCGCTATTTTTATAGCCATGTTCTTGTCGCCCTTGATGGCAGTTTTTGTC
    ATCCTAGCCTCTAGTTTTGGATTTTTGATGGCTGGCTATCCCATGGTTATCGTTTTTCGG
    GCTTTTTCCCATATATCTTTTGGTGCTTTAGGAGCTCTTTACCTACAAAAATTCCCCGAT
    ACCCTAGATAAACCAAAATCTTCCTGGGTTTTCAATTTTGTTTTGGCTGTTGTTCATGCC
    CTTGCTGAAGTATTAGCCTGTGTCCTTTTTTACGCAACTTCGGGTACCAATGTAGAAAAT
    ATGTTCTATGTTCTATTTGTACTAGTTGGATTTGGCACAATTATCCATAGTATGGTAGAC
    TATACATTAGCACTAGCTGTCTATAAAGTGCTTCGAAAACGCCGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    528

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPV_1091 [new locus tag: SPV_RS05830 ]
  • symbol: NiaX
  • description: Substrate-specific component NiaX of putative niacin ECF transporter
  • length: 175
  • theoretical pI: 10.2713
  • theoretical MW: 19432.4
  • GRAVY: 1.01943

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Gx_transp (CL0315) ECF-ribofla_trS; ECF-type riboflavin transporter, S component (PF07155; HMM-score: 26.3)
    and 1 more
    ECF_trnsprt; ECF transporter, substrate-specific component (PF12822; HMM-score: 18.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9973
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0025
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.023004
    • TAT(Tat/SPI): 0.002228
    • LIPO(Sec/SPII): 0.05816
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AVN86194 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHIAIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTLDKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVDYTLALAVYKVLRKRR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: NiaR (repression) regulon
    NiaR(TF)important in NAD biosynthesis;  – regulation transferred from D39 see SPD_1091

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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