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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-FEB-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39V
  • locus tag: SPV_1171 [new locus tag: SPV_RS06245 ]
  • pan locus tag?: PNEUPAN002658000
  • symbol: SPV_1171
  • pan gene symbol?: nanM
  • synonym:
  • product: N-acetylneuraminate epimerase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPV_1171 [new locus tag: SPV_RS06245 ]
  • symbol: SPV_1171
  • product: N-acetylneuraminate epimerase
  • replicon: chromosome
  • strand: -
  • coordinates: 1200537..1201460
  • length: 924
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP027540 (1200537..1201460) NCBI
  • BioCyc: SPV_1171 BioCyc
  • MicrobesOnline:
  • PneumoBrowse: SPV_1171 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAAAATTGATGTTATAAATCATTTAGACTCACCAGGATTAGCTGGGATGATTTGTAGA
    CGGATTAATAATAGAATTTTAGTTTATGGAGGTAGTTATTTCCCAAATAACGATCCTTTA
    AAAAGTTCAAAAGTTCAATCAAATAAAATTAGAGTTTATGATGAGAAATTTAATCTTCTA
    TATGAACAAGATGGAAAAATTTCTCCAGATAAAGGAATAACGATTGAAGTTGAAAATGAA
    ATCTATTACATTCTAGGCTCGAGCATTTATCGTATTACGATTGGTGAAAGTGTAGAAGAA
    ACCTGTATCGGGAATTTTGATTTCCAACTAGAGAGTGGTTATGGTTGTTATTTTGATGGC
    CACTTATTCTTTGGATTTCAGGAAAGTTATTTGTTCAATATTGAGACTCAAGAGCTTTTT
    AAAAAATCTGACTTCCCAGTTTCTGGTAGAGGCCAAGGTTTGTCAGTCAAATATCAAAAT
    GAATTGTATTATTTAGGTGGAGCGAACAATGAAGCTTATTTAGATGGATACAAATATAGT
    TTAAAAAAAGATAAGTGGGAAAAACTTGAGTTCGAATTACCAAGCTCAGTTCTAGGAGCA
    TCAAGTATACAAATAAATGAAAGTGGTTTATTAATACTTGGTGGCTTTAATGAAATTGTT
    TATAATAAAGCAGTTATTGATTTAGCAACCCCTGGCTATAGGGAAGAATATTTTTCTAAA
    GGGAGAGATTTCTTTAATTGGAATCGTAGCATGCGAATACTAGATTTAGAGACAGGTAAG
    GTCAAGATTATTGCAAACGATGAGCGTTTTGCTCTTTGTGGGGCAGGATTTTTAAAAACT
    GATAATGGATATTACGTTGTTAGTGGGGAATGTAGCCCAGGAAGACGTACTTCTGACATA
    CTTTTGTTAGAGGAGGAAATGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    924

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPV_1171 [new locus tag: SPV_RS06245 ]
  • symbol: SPV_1171
  • description: N-acetylneuraminate epimerase
  • length: 307
  • theoretical pI: 4.62263
  • theoretical MW: 34907.1
  • GRAVY: -0.334853

⊟Function[edit | edit source]

  • reaction:
    EC 5.1.3.24?  ExPASy
    N-acetylneuraminate epimerase N-acetyl-alpha-neuraminate = N-acetyl-beta-neuraminate
  • TIGRFAM:
    cyclically-permuted mutarotase family protein (TIGR03548; HMM-score: 348.5)
    and 1 more
    mutatrotase, YjhT family (TIGR03547; EC 5.1.-.-; HMM-score: 88.8)
  • TheSEED: data available for D39
  • PFAM:
    Beta_propeller (CL0186) Kelch_2; Kelch motif (PF07646; HMM-score: 34.9)
    Kelch_6; Kelch motif (PF13964; HMM-score: 33.8)
    and 3 more
    Kelch_4; Galactose oxidase, central domain (PF13418; HMM-score: 23.9)
    Kelch_1; Kelch motif (PF01344; HMM-score: 17.8)
    Kelch_3; Galactose oxidase, central domain (PF13415; HMM-score: 17.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016774
    • TAT(Tat/SPI): 0.001009
    • LIPO(Sec/SPII): 0.007104
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AVN86269 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSKVQSNKIRVYDEKFNLLYEQDGKISPDKGITIEVENEIYYILGSSIYRITIGESVEETCIGNFDFQLESGYGCYFDGHLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQNELYYLGGANNEAYLDGYKYSLKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNEIVYNKAVIDLATPGYREEYFSKGRDFFNWNRSMRILDLETGKVKIIANDERFALCGAGFLKTDNGYYVVSGECSPGRRTSDILLLEEEM

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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