From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39V
  • locus tag: SPV_RS03690 [old locus tag: SPV_0685 ]
  • pan locus tag?: PNEUPAN001733000
  • symbol: gor
  • pan gene symbol?: gor
  • synonym:
  • product: glutathione-disulfide reductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPV_RS03690 [old locus tag: SPV_0685 ]
  • symbol: gor
  • product: glutathione-disulfide reductase
  • replicon: chromosome
  • strand: -
  • coordinates: 699575..700921
  • length: 1347
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGAGAGAATATGATATCATTGCTATCGGTGGAGGTAGCGGAGGAATCGCTACCATGAAC
    CGTGCTGGTGAACATGGAGCCCAAGCAGCCGTTATTGAGGAAAAGAAATTAGGTGGAACC
    TGTGTCAACGTCGGTTGTGTTCCTAAAAAAATCATGTGGTACGGGGCACAAATCGCTGAG
    ACTTTCCATCAATTTGGAGAAGACTACGGCTTTAAGACTACTGATCTTAACTTTGACTTT
    GCAACCCTACGTCGCAATCGTGAATCCTACATTGATCGCGCTCGTTCTTCTTATGATGGC
    AGTTTTAAACGCAACGGTGTAGACTTGATTGAAGGTCATGCTGAATTTGTAGATTCTCAT
    ACTGTAAGCGTAAATGGTGAACTGATTCGTGCTAAACATATCGTGATTGCTACAGGTGCC
    CATCCAAGTATTCCTAATATTCCTGGTGCTGAGCTAGGTGGCTCTTCTGATGATGTATTT
    GCCTGGGAAGAACTTCCAGAGTCAGTTGCCATTCTAGGCGCTGGTTATATCGCCGTTGAA
    TTAGCTGGCGTACTCCACACTTTTGGTGTCAAGACAGATCTCTTTGTTCGCCGCGATCGT
    CCTTTACGTGGTTTTGATTCCTACATCGTTGAAGGTTTGGTCAAGGAAATGGAAAGAACA
    AACTTACCACTTCACACTCACAAAGTCCCTGTCAAGTTAGAAAAAACTACTGACGGCATT
    ACCATTCATTTCGAAGATGGTACTAGTCACACAGCTAGCCAAGTTATCTGGGCTACAGGC
    CGCCGTCCAAACGTTAAGGGCTTGCAACTTGAAAAAGCTGGAGTGACTCTGAACGAACGT
    GGCTTTATCCAAGTGGATGAATACCAAAATACTGTTGTTGAGGGAATCTATGCTCTAGGT
    GATGTAACGGGCGAGAAAGAACTGACTCCAGTTGCAATCAAGGCCGGACGTACCCTATCT
    GAACGTCTCTTTAACGGAAAAACTACTGCAAAAATGGATTACTCAACTATTCCAACTGTT
    GTCTTTTCACACCCTGCTATCGGAACTGTTGGTTTGACAGAAGAGCAAGCTATTAAAGAA
    TACGGTCAAGACCAAATCAAGGTTTACAAATCAAGCTTTGCATCTATGTACTCTGCTTGC
    ACTCGCAACCGTCAAGAATCCCGTTTCAAACTCATAACAGCTGGTTCAGAAGAAAAAGTT
    GTCGGACTTCATGGAATTGGCTACGGCGTTGATGAAATGATTCAGGGATTTGCCGTTGCT
    ATCAAAATGGGAGCAACCAAGGCTGACTTTGACGCAACTGTAGCGATTCACCCAACTTCA
    TCTGAAGAATTTGTAACCATGCGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1347

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPV_RS03690 [old locus tag: SPV_0685 ]
  • symbol: Gor
  • description: glutathione-disulfide reductase
  • length: 448
  • theoretical pI: 6.16283
  • theoretical MW: 48860.9
  • GRAVY: -0.210938

⊟Function[edit | edit source]

  • reaction:
    EC 1.8.1.7?  ExPASy
    Glutathione-disulfide reductase 2 glutathione + NADP+ = glutathione disulfide + NADPH
  • TIGRFAM:
    Metabolism Energy metabolism Electron transport glutathione-disulfide reductase (TIGR01421; EC 1.8.1.7; HMM-score: 794.3)
    and 25 more
    Metabolism Energy metabolism Electron transport glutathione-disulfide reductase (TIGR01424; EC 1.8.1.7; HMM-score: 456.2)
    thioredoxin and glutathione reductase (TIGR01438; EC 1.6.4.-; HMM-score: 367.9)
    dihydrolipoyl dehydrogenase (TIGR01350; EC 1.8.1.4; HMM-score: 340.6)
    Cellular processes Cellular processes Detoxification mercury(II) reductase (TIGR02053; EC 1.16.1.1; HMM-score: 309.1)
    trypanothione-disulfide reductase (TIGR01423; EC 1.8.1.12; HMM-score: 293.5)
    mycothione reductase (TIGR03452; EC 1.8.1.15; HMM-score: 261.7)
    Cellular processes Cellular processes Detoxification CoA-disulfide reductase (TIGR03385; EC 1.8.1.14; HMM-score: 94.1)
    Metabolism Central intermediary metabolism Nitrogen metabolism nitrite reductase [NAD(P)H], large subunit (TIGR02374; EC 1.7.1.4; HMM-score: 55)
    Metabolism Energy metabolism Electron transport thioredoxin-disulfide reductase (TIGR01292; EC 1.8.1.9; HMM-score: 54.2)
    Unknown function Enzymes of unknown specificity putative bacillithiol system oxidoreductase, YpdA family (TIGR04018; EC 1.8.-.-; HMM-score: 42.8)
    pyridine nucleotide-disulfide oxidoreductase family protein (TIGR03169; HMM-score: 38.9)
    Cellular processes Cellular processes Detoxification alkyl hydroperoxide reductase subunit F (TIGR03140; EC 1.8.1.-; HMM-score: 33.1)
    Cellular processes Cellular processes Adaptations to atypical conditions alkyl hydroperoxide reductase subunit F (TIGR03140; EC 1.8.1.-; HMM-score: 33.1)
    putative alkyl hydroperoxide reductase F subunit (TIGR03143; EC 1.6.4.-; HMM-score: 32.4)
    Metabolism Amino acid biosynthesis Glutamate family glutamate synthase (NADPH), homotetrameric (TIGR01316; EC 1.4.1.13; HMM-score: 30.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll geranylgeranyl reductase family (TIGR02032; EC 1.3.1.-; HMM-score: 17)
    glutamate synthase, small subunit (TIGR01318; HMM-score: 16.4)
    Unknown function Enzymes of unknown specificity flavoprotein, HI0933 family (TIGR00275; HMM-score: 16)
    glutamate synthase, NADH/NADPH, small subunit (TIGR01317; EC 1.4.1.-; HMM-score: 15.2)
    Metabolism Energy metabolism Amino acids and amines sarcosine oxidase, beta subunit family (TIGR01373; HMM-score: 14.1)
    Metabolism Energy metabolism Electron transport flavocytochrome c (TIGR01813; HMM-score: 12.3)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-galactopyranose mutase (TIGR00031; EC 5.4.99.9; HMM-score: 12)
    salicylate 1-monooxygenase (TIGR03219; EC 1.14.13.1; HMM-score: 11.6)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain (TIGR03197; HMM-score: 11.4)
    Metabolism Energy metabolism Amino acids and amines sarcosine oxidase, alpha subunit family (TIGR01372; HMM-score: 9.7)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    NADP_Rossmann (CL0063) Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase (PF07992; HMM-score: 215.5)
    and 10 more
    Reductase_C (CL0608) Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain (PF02852; HMM-score: 122.4)
    NADP_Rossmann (CL0063) Pyr_redox_3; Pyridine nucleotide-disulphide oxidoreductase (PF13738; HMM-score: 65.7)
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase (PF00070; HMM-score: 61.5)
    HI0933_like; HI0933-like protein (PF03486; HMM-score: 24.2)
    Lys_Orn_oxgnase; L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase (PF13434; HMM-score: 17.2)
    FAD_oxidored; FAD dependent oxidoreductase (PF12831; HMM-score: 16.3)
    NAD_binding_9; FAD-NAD(P)-binding (PF13454; HMM-score: 13.4)
    DAO; FAD dependent oxidoreductase (PF01266; HMM-score: 12.6)
    FAD_binding_2; FAD binding domain (PF00890; HMM-score: 7.5)
    GIDA; Glucose inhibited division protein A (PF01134; HMM-score: 5.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9057
    • Cytoplasmic Membrane Score: 0.0861
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0081
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.127764
    • TAT(Tat/SPI): 0.115708
    • LIPO(Sec/SPII): 0.010403
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001209604 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MREYDIIAIGGGSGGIATMNRAGEHGAQAAVIEEKKLGGTCVNVGCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSFKRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVFAWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEMERTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVTLNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDYSTIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLITAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPV_RS03690&oldid=67356"