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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39V
  • locus tag: SPV_RS07860 [old locus tag: SPV_1480 ]
  • pan locus tag?: PNEUPAN003083000
  • symbol: ftsA
  • pan gene symbol?: ftsA
  • synonym:
  • product: cell division protein FtsA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPV_RS07860 [old locus tag: SPV_1480 ]
  • symbol: ftsA
  • product: cell division protein FtsA
  • replicon: chromosome
  • strand: -
  • coordinates: 1495936..1497309
  • length: 1374
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGCTAGAGAAGGCTTTTTTACAGGTCTAGATATTGGAACAAGCTCTGTCAAGGTGCTT
    GTGGCCGAGCAGAGAAATGGTGAATTAAATGTAATTGGCGTGAGTAATGCCAAAAGTAAA
    GGTGTAAAGGATGGAATTATTGTTGATATTGATGCAGCAGCAACTGCTATCAAGTCAGCC
    ATTTCCCAAGCGGAAGAAAAGGCAGGCATTTCGATTAAATCAGTGAATGTCGGCTTGCCT
    GGTAATCTTTTGCAGGTAGAACCAACTCAGGGGATGATTCCAGTAACATCTGATACTAAG
    GAAATTACGGATCAAGATGTTGAAAATGTTGTCAAATCAGCTTTGACAAAGAGTATGACA
    CCTGACCGTGAAGTCATTACCTTTATTCCTGAAGAATTTATTGTGGATGGTTTCCAAGGG
    ATTCGTGACCCACGTGGCATGATGGGGGTTCGCCTTGAAATGCGTGGTTTGCTTTATACA
    GGACCTCGTACTATCTTGCACAATTTGCGTAAGACGGTTGAGCGTGCAGGTGTTCAGGTT
    GAAAATGTTATCATTTCACCACTAGCAATGGTTCAGTCTGTTTTGAACGAAGGGGAACGT
    GAATTTGGTGCTACAGTGATTGATATGGGGGCAGGTCAAACGACTGTCGCTACAATCCGT
    AATCAAGAACTCCAGTTCACACATATTCTCCAAGAAGGTGGAGATTATGTAACTAAAGAT
    ATCTCCAAGGTTTTGAAAACCTCTCGCAAATTAGCGGAAGGCTTAAAACTGAATTACGGG
    GAAGCCTATCCGCCTCTTGCAAGCAAAGAAACCTTCCAAGTAGAGGTTATTGGAGAAGTA
    GAAGCAGTCGAAGTGACGGAAGCCTACTTGTCAGAAATTATTTCTGCACGAATCAAGCAC
    ATCCTTGAACAAATCAAGCAAGAATTAGATAGAAGGCGTCTATTGGACCTCCCTGGTGGT
    ATTGTCTTAATCGGTGGGAATGCCATTTTACCAGGTATGGTTGAGCTTGCTCAGGAAGTC
    TTTGGCGTCCGTGTCAAGCTTTATGTTCCAAATCAAGTTGGTATCCGTAATCCAGCCTTT
    GCGCATGTGATTAGTTTATCAGAATTTGCGGGTCAATTAACAGAAGTTAATCTTTTGGCT
    CAGGGAGCGATAAAAGGTGAGAATGACTTAAGTCATCAGCCAATTAGTTTTGGTGGGATG
    CTGCAAAAAACAGCTCAGTTTGTACAATCAACGCCTGTTCAACCAGCTCCTGCTCCAGAA
    GTAGAGCCGGTGGCGCCTACAGAACCAATGGCGGATTTCCAACAAGCTTCACAAAATAAA
    CCGAAATTAGCAGATCGTTTCCGTGGCTTGATCGGAAGCATGTTTGACGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1374

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPV_RS07860 [old locus tag: SPV_1480 ]
  • symbol: FtsA
  • description: cell division protein FtsA
  • length: 457
  • theoretical pI: 4.83428
  • theoretical MW: 49474.4
  • GRAVY: -0.0628009

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Cell division cell division protein FtsA (TIGR01174; HMM-score: 335)
    and 4 more
    type IV pilus assembly protein PilM (TIGR01175; HMM-score: 45.4)
    ethanolamine utilization protein EutJ family protein (TIGR02529; HMM-score: 38.2)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan cell shape determining protein, MreB/Mrl family (TIGR00904; HMM-score: 37.7)
    Metabolism Energy metabolism Sugars xylulokinase (TIGR01312; EC 2.7.1.17; HMM-score: 10.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Actin_ATPase (CL0108) FtsA; Cell division protein FtsA (PF14450; HMM-score: 87.5)
    SHS2 (CL0319) SHS2_FTSA; SHS2 domain inserted in FTSA (PF02491; HMM-score: 81.2)
    and 5 more
    no clan defined FtsA_C; Cell division protein FtsA, C-terminal (PF11983; HMM-score: 62.2)
    Actin_ATPase (CL0108) MreB_Mbl; MreB/Mbl protein (PF06723; HMM-score: 53.3)
    PilM_2; Type IV pilus assembly protein PilM; (PF11104; HMM-score: 37.5)
    DDR; Diol dehydratase reactivase ATPase-like domain (PF08841; HMM-score: 16.8)
    FGGY_N; FGGY family of carbohydrate kinases, N-terminal domain (PF00370; HMM-score: 14.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8205
    • Cytoplasmic Membrane Score: 0.1363
    • Cell wall & surface Score: 0.0015
    • Extracellular Score: 0.0418
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008694
    • TAT(Tat/SPI): 0.003278
    • LIPO(Sec/SPII): 0.002478
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000090397 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKDGIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEITDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYTGPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVATIRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEVIGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMVELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSHQPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGLIGSMFDE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Beatriz Lara, Ana Isabel Rico, Sabrina Petruzzelli, Antonella Santona, Jacques Dumas, Jacques Biton, Miguel Vicente, Jesús Mingorance, Orietta Massidda
Cell division in cocci: localization and properties of the Streptococcus pneumoniae FtsA protein.
Mol Microbiol: 2005, 55(3);699-711
[PubMed:15660997] [WorldCat.org] [DOI] (P p)

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