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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_0141 [new locus tag: SP_RS00725 ]
  • pan locus tag?: PNEUPAN000851000
  • symbol: SP_0141
  • pan gene symbol?: mutR1
  • synonym:
  • product: transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_0141 [new locus tag: SP_RS00725 ]
  • symbol: SP_0141
  • product: transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 139839..140702
  • length: 864
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATTGAGAGAATGGAACTGGGGGAATTTTACAAGGAATTACGTTTGGCGAGAAAGCTC
    AAGCAGTCAGATGTGGCTTGTGAGGGTCTAACAGCTTCTCAGTTGTCCAAGTTTGAACTA
    GGGCAGTCTATGCTGTCTGCGGATAAGTTGATTCTAGCTATCCAAGGTATAAATGTGACC
    TTTGATGAGTTTGGGCACAAGCTCAACAACTATCAAGAATCTCCACATATGCGAATCGGT
    CGAAAGGTTGTGAATCGCTTTGCCCATCAGGATATAGCTGCTTTAGAGCAGCTATTGGAG
    GAAGTCGATCAAGAACAGATGGCGCAGACCTATCGTCGTTTGAATGCCATCGTGATTAAA
    GATGCCATCCATTCACTAAATAAAAGCTACCCACTAGCAGAGGAGGATAGCGAGTTTTTG
    ACCACCTATCTCTATGCTATCGAGTCTTGGACCTGGTTTGAACTCTATCTCTTTTGCAAT
    ACCATGCCCTTCTTGAGCAATCAAGATCTGATTTTTTTATCAACCTCCTTACTCGAAAAA
    TCCAAAGAATTTAAAGAGTTAGTACACAATCGATTGTATATGAAGCAAGGACTCTTAAAT
    ATCTTATCAGAACTCATGGAGCGAAAACTTTTCTCCTACATCCCAATCTTCGAAGCCGAG
    TTGGAGAGGATGTTACGACCGTATGATGTTTTTGAAAAAGTATCGTGGCAATTTTTAAAG
    AAGATGAGTGTCTTTCTTCAAACAAAGGGAAGCAATCAAAAAGAGATTGAACGCTTTATC
    CAATCTCTGCAGGTATTAGAAAATCCACAATTAATAGCCCTTTTTGAATTGCGTTTTCAG
    CAATATAAAGAACTTATAGATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    864

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_0141 [new locus tag: SP_RS00725 ]
  • symbol: SP_0141
  • description: transcriptional regulator
  • length: 287
  • theoretical pI: 5.28983
  • theoretical MW: 33957.1
  • GRAVY: -0.243206

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional activator, Rgg/GadR/MutR family, C-terminal domain (TIGR01716; HMM-score: 225)
  • TheSEED  :
    • Positive transcriptional regulator, MutR family
  • PFAM:
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 25.4)
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 24.7)
    and 3 more
    no clan defined CENP-U; CENP-A nucleosome associated complex (NAC) subunit (PF13097; HMM-score: 15.9)
    Trigger_C (CL0262) SurA_N_2; SurA N-terminal domain (PF13623; HMM-score: 15)
    no clan defined GlutR_dimer; Glutamyl-tRNAGlu reductase, dimerisation domain (PF00745; HMM-score: 14.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004137
    • TAT(Tat/SPI): 0.000459
    • LIPO(Sec/SPII): 0.000831
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIERMELGEFYKELRLARKLKQSDVACEGLTASQLSKFELGQSMLSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEVDQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCNTMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFEAELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLIALFELRFQQYKELID

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY (activation (repression)) regulon
    CodY(TF)important in Amino acid metabolism; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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