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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_0418 [new locus tag: SP_RS02065 ]
- pan locus tag?: PNEUPAN001287000
- symbol: acpP
- pan gene symbol?: acpP
- synonym:
- product: acyl carrier protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_0418 [new locus tag: SP_RS02065 ]
- symbol: acpP
- product: acyl carrier protein
- replicon: chromosome
- strand: +
- coordinates: 396692..396916
- length: 225
- essential: yes [1]
⊟Accession numbers[edit | edit source]
- Location: AE005672 (396692..396916) NCBI
- BioCyc: see SP_RS02065
- MicrobesOnline: 115940 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_0381 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181ATGGCAGTATTTGAAAAAGTACAAGAAATTATCGTTGAAGAACTTGGAAAAGACGCATCA
GAAGTAACACTTGAATCAACTTTTGATGATTTGGACGCAGATTCATTGGACTTGTTCCAA
GTAATCTCAGAAATCGAAGATGCTTTTGATATCCAAATCGAAGCAGAAAATGACTTGAAA
ACAGTTGGTGACTTGGTTGCTTACGTTGAAGAGCAAGCAAAATAA60
120
180
225
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_0418 [new locus tag: SP_RS02065 ]
- symbol: AcpP
- description: acyl carrier protein
- length: 74
- theoretical pI: 3.42461
- theoretical MW: 8268.04
- GRAVY: -0.0621622
⊟Function[edit | edit source]
- TIGRFAM: Fatty acid and phospholipid metabolism Biosynthesis acyl carrier protein (TIGR00517; HMM-score: 62.1)and 1 moreCellular processes Toxin production and resistance peptide maturation system acyl carrier-related protein (TIGR04069; HMM-score: 13.6)
- TheSEED :
- Acyl carrier protein
and 1 more - PFAM: PP-binding (CL0314) PP-binding; Phosphopantetheine attachment site (PF00550; HMM-score: 53)and 1 moreno clan defined KIP1; KIP1-like protein (PF07765; HMM-score: 12.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002092
- TAT(Tat/SPI): 0.000091
- LIPO(Sec/SPII): 0.000202
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISEIEDAFDIQIEAENDLKTVGDLVAYVEEQAK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: FabT* (repression) regulon
FabT* (TF) important in Fatty acid biosynthesis; RegPrecise
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0381 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Tim van Opijnen, Andrew Camilli
A fine scale phenotype-genotype virulence map of a bacterial pathogen.
Genome Res: 2012, 22(12);2541-51
[PubMed:22826510] [WorldCat.org] [DOI] (I p)