Jump to navigation
Jump to search
PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_1110 [new locus tag: SP_RS05495 ]
- pan locus tag?: PNEUPAN002257000
- symbol: SP_1110
- pan gene symbol?: ribF
- synonym:
- product: macrolide-efflux protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_1110 [new locus tag: SP_RS05495 ]
- symbol: SP_1110
- product: macrolide-efflux protein
- replicon: chromosome
- strand: +
- coordinates: 1039154..1040071
- length: 918
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AE005672 (1039154..1040071) NCBI
- BioCyc: see SP_RS05495
- MicrobesOnline: 116580 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_0994 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901ATGATTATTACTATTCCTATAAAAAACCAAAAAGATATTGGCACACCATCTGATTCAGTC
GTTGTTCTCGGCTATTTTGATGGCATACATAAGGGGCATCAAGAATTATTTCGTGTTGCC
AACAAGGCTGCGAGAAAGGATTTGTTGCCTATCGTCGTTATGACCTTTAATGAATCTCCA
AAGATCGCTTTAGAGCCTTATCATCCAGATTTGTTTTTGCATATTTTGAACCCTGCTGAA
CGTGAAAGAAAATTAAAGCGCGAAGGTGTAGAAGAATTATATCTCCTTGATTTTAGTAGT
CAATTCGCTAGTCTCACTGCACAAGAATTCTTTGCAACTTATATCAAGGCTATGAATGCC
AAAATTATTGTTGCAGGTTTTGATTATACATTTGGTTCTGACAAAAAAACAGCAGAAGAT
TTAAAGAATTACTTTGATGGAGAAGTTATCATTGTTCCACCTGTAGAAGATGAGAAAGGA
AAGATTAGTTCAACTCGTATCCGTCAAGCTATTTTAGATGGAAATGTGAAAGAAGCAGGA
AAACTTTTGGGGGCACCGCTTCCATCAAGAGGTATGGTGGTTCATGGTAATGCTCGTGGT
CGTACAATTGGTTATCCGACAGCGAATTTAGTGCTTTTAGACCGTACTTATATGCCAGCA
GATGGCGTTTATGTTGTTGATGTTGAGATTCAAAGACAGAAGTATCGTGCTATGGCTAGT
GTCGGGAAAAATGTGACCTTTGATGGAGAAGAAGCACGTTTTGAAGTCAATATTTTTGAT
TTTAATCAAGATATTTATGGGGAAACCGTCATGGTTTATTGGCTTGATCGCATTCGAGAT
ATGACCAAATTTGACTCAGTTGACCAATTAGTGGATCAGTTAAAGGCTGATGAAGAAGTA
ACTCGGAATTGGTCTTAA60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
918
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_1110 [new locus tag: SP_RS05495 ]
- symbol: SP_1110
- description: macrolide-efflux protein
- length: 305
- theoretical pI: 5.27951
- theoretical MW: 34521.2
- GRAVY: -0.250164
⊟Function[edit | edit source]
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Riboflavin, FMN, and FAD riboflavin biosynthesis protein RibF (TIGR00083; EC 2.7.1.26,2.7.7.2; HMM-score: 248.7)and 4 morecytidyltransferase-like domain (TIGR00125; HMM-score: 28.4)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides bifunctional protein RfaE, domain II (TIGR02199; EC 2.7.7.-; HMM-score: 15.6)nicotinamide-nucleotide adenylyltransferase (TIGR01526; EC 2.7.7.1; HMM-score: 15.4)Biosynthesis of cofactors, prosthetic groups, and carriers Pyridine nucleotides nicotinate (nicotinamide) nucleotide adenylyltransferase (TIGR00482; EC 2.7.7.18; HMM-score: 13.2)
- TheSEED :
- FMN adenylyltransferase (EC 2.7.7.2)
- Riboflavin kinase (EC 2.7.1.26)
Cofactors, Vitamins, Prosthetic Groups, Pigments Riboflavin, FMN, FAD riboflavin to FAD FMN adenylyltransferase (EC 2.7.7.2)and 2 more - PFAM: HUP (CL0039) FAD_syn; FAD synthetase (PF06574; HMM-score: 141.1)no clan defined Flavokinase; Riboflavin kinase (PF01687; HMM-score: 120.9)and 1 moreHUP (CL0039) CTP_transf_like; Cytidylyltransferase-like (PF01467; HMM-score: 24.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002029
- TAT(Tat/SPI): 0.000147
- LIPO(Sec/SPII): 0.000283
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAARKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQFASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKNYFDGEVIIVPPVEDEKGKISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYMPADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLDRIRDMTKFDSVDQLVDQLKADEEVTRNWS
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0994 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Jelle Slager, Rieza Aprianto, Jan-Willem Veening
Refining the Pneumococcal Competence Regulon by RNA Sequencing.
J Bacteriol: 2019, 201(13);
[PubMed:30885934] [WorldCat.org] [DOI] (I e)